Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene.

Title

Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene.

Creator

Chiang J Y; Yang T P; Wang D P

Publisher

Biochimica et biophysica acta

Date

1992
1992-10

Description

A cholesterol 7 alpha-hydroxylase gene containing 8 kb of the 5'-flanking region and 5 kb of the transcription region which covers exons 1 to 5 was isolated from a rat genomic library. The 2015 bp nucleotide sequence 5'-upstream from the start codon was determined. This promotor region contains many liver-enriched or -specific elements (TGT3, HNF/LF-B1), putative hormone responsive elements (TRE, GRE, RRE or RARE) and ubiquitous transcription factor binding sites (NF-1,

Subject

Animals; Rats; Amino Acid Sequence; Base Sequence; Molecular Sequence Data; Cholesterol 7-alpha-Hydroxylase/*genetics; DNA; Restriction Mapping; Genetic; Cloning; Molecular; *Promoter Regions

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

337–339

Issue

3

Volume

1132

Citation

Chiang J Y; Yang T P; Wang D P, “Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene.,” NEOMED Bibliography Database, accessed December 3, 2021, https://neomed.omeka.net/items/show/5344.

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