[Clinical impact of appropriate use of antibiotic in hospital according to CARAT criteria].

[Clinical impact of appropriate use of antibiotic in hospital according to CARAT criteria].

File Thomas M Jr

Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive

2008

2008-04

In response to the overuse and misuse of antibiotics, leading to increasing bacterial resistance and the decreasing development of new antibiotics, the Council for Appropriate and Rational Antibiotic Therapy (an independent, interdisciplinary panel of healthcare professionals established to advocate the appropriate use of antibiotics) has developed criteria to guide proper antibiotic selection. These criteria include: establishment of a need to justify use of antibiotics (e.g., colonization versus disease); evidence-based results; therapeutic benefits; safety; use of pharmacodynamic indices for optimal drug and optimal duration; cost-effectiveness. Promoting the appropriate use of antibiotics should provide for optimal outcomes for our patients.

Humans; *Practice Guidelines as Topic; Intensive Care Units; Anti-Bacterial Agents/pharmacology/*therapeutic use; Evidence-Based Medicine; Organizational Policy; Europe/epidemiology; Clinical Trials as Topic; *Guideline Adherence; Bacterial Infections/drug therapy/epidemiology; Drug Utilization; Hospitals/*standards; Patients' Rooms; *Drug Resistance; Multiple; Bacterial

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

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16 Suppl2