Disseminated brown tumors from hyperparathyroidism masquerading as metastatic cancer: a complication of parathyroid carcinoma.

Title

Disseminated brown tumors from hyperparathyroidism masquerading as metastatic cancer: a complication of parathyroid carcinoma.

Creator

Gupta A; Horattas M C; Moattari A R; Shorten S D

Publisher

The American surgeon

Date

2001
2001-10

Description

Osteitis fibrosa cystica (brown tumors) can be a skeletal manifestation of advanced hyperparathyroidism, including parathyroid cancer. Severe osteitis fibrosa cystica can mimic metastatic bone diseases especially in patients with a history of cancer. Because the treatment and prognosis of these two problems differ greatly considering hyperparathyroidism in the differential diagnosis of patients found to have osteolytic lesions is critical for the appropriate management of these patients. In this case report we describe a patient with a history of renal cell cancer and presumed osteolytic bone metastases. During prophylactic intramedullary rodding to prevent pathologic fracture of her femur she was found to have a benign lesion related to her previously undiagnosed hyperparathyroidism caused by an underlying parathyroid cancer. A detailed review of this disease and the associated bone changes is also included to underscore the importance of an adequate differential diagnosis as well as optimal management. Patients with hypercalcemia or bony lesions should not automatically be treated palliatively for metastatic disease just because of a past medical history of cancer. Hyperparathyroidism is a readily curable problem if properly diagnosed.

Subject

Female; Humans; Middle Aged; Carcinoma/*complications; Hyperparathyroidism/complications; Kidney Neoplasms/pathology; Osteitis Fibrosa Cystica/*diagnosis/*etiology; Parathyroid Neoplasms/*complications; Diagnosis; Carcinoma; Differential; Renal Cell/secondary

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

951–955

Issue

10

Volume

67

Citation

Gupta A; Horattas M C; Moattari A R; Shorten S D, “Disseminated brown tumors from hyperparathyroidism masquerading as metastatic cancer: a complication of parathyroid carcinoma.,” NEOMED Bibliography Database, accessed May 18, 2021, https://neomed.omeka.net/items/show/5451.

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