Side effects of the use of botulinum toxin for treatment of benign essential blepharospasm and hemifacial spasm.

Title

Side effects of the use of botulinum toxin for treatment of benign essential blepharospasm and hemifacial spasm.

Creator

Kalra H K; Magoon E H

Publisher

Ophthalmic surgery

Date

1990
1990-05

Description

From April 1983 to April 1988, 381 botulinum toxin injections for lid spasms were administered to 106 patients. Sixty-nine had bilateral blepharospasm and 37 had hemifacial spasm. Of the 381 injections, 308 had been given to patients who returned for follow-up examinations. No systemic effects were noted at any of these visits; all side effects were temporary; there were no serious complications. Ptosis, the most frequently encountered problem, occurred after 26 (8.4%) of the injections. Other complications included: corneal exposure (after eight injections, 2.59%); face droop (after 11 injections, 3.57%); diplopia (after five injections, 1.62%); and subtle visual blurring (after eight injections, 2.59%). One patient noted jaw tenseness, another mentioned tearing, one reported brow droop, and another complained of crossed eyes. Ten injections had minimal effect; in these cases a repeat injection usually was effective. Only four patients chose surgery after beginning injections. We conclude that botulinum toxin injections are a safe, effective means of treating lid spasms.

Subject

Female; Humans; Male; Adolescent; Prognosis; Blepharoptosis/chemically induced; Blepharospasm/*drug therapy; Botulinum Toxins/*adverse effects/therapeutic use; Diplopia/chemically induced; Dry Eye Syndromes/chemically induced; Eyelid Diseases/*drug therapy; Facial Muscles/*drug effects; Spasm/*drug therapy; Vision Disorders/chemically induced

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

335–338

Issue

5

Volume

21

Citation

Kalra H K; Magoon E H, “Side effects of the use of botulinum toxin for treatment of benign essential blepharospasm and hemifacial spasm.,” NEOMED Bibliography Database, accessed February 27, 2024, https://neomed.omeka.net/items/show/5470.