Frictional asymptomatic darkening of the extensor surfaces.

Title

Frictional asymptomatic darkening of the extensor surfaces.

Creator

Krishnamurthy Smita; Sigdel Saroj; Brodell Robert T

Publisher

Cutis

Date

2005
2005-06

Description

Frictional asymptomatic darkening of the extensor surfaces (FADES), also known as hyperkeratosis of the elbows and knees, is commonly seen by dermatologists but has never been well characterized. Patients present with uniform, asymptomatic, brown darkening over the extensor surfaces of the elbows and knees with minimal scaling. Both frictional stress and family history may play a role in the pathogenesis of this condition. The results of cutaneous biopsy specimens typically reveal hyperkeratosis, acanthosis, and mild papillomatosis with minimal inflammation. Keratolytic agents such as lactic acid and urea cream along with avoiding frictional stress can be effective in the management of this condition. We describe a series of cases of FADES and its etiology and management options.

Subject

Adult; Humans; Male; Middle Aged; Aged; Elbow; *Friction; Keratosis/*diagnosis/drug therapy/*etiology; Knee; Diagnosis; Differential

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

349–355

Issue

6

Volume

75

Citation

Krishnamurthy Smita; Sigdel Saroj; Brodell Robert T, “Frictional asymptomatic darkening of the extensor surfaces.,” NEOMED Bibliography Database, accessed May 8, 2021, https://neomed.omeka.net/items/show/5491.

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