Incorporating the Oncotype DX breast cancer assay into community practice: an expert Q&A and case study sampling.

Title

Incorporating the Oncotype DX breast cancer assay into community practice: an expert Q&A and case study sampling.

Creator

Mamounas Eleftherios P; Budd G Thomas; Miller Kathy D

Publisher

Clinical advances in hematology & oncology : H&O

Date

2008
2008-02

Description

Advances in breast cancer research have confirmed that this malignancy is not a single disease, but rather a collection of genetically distinct diseases with different treatment requirements. In recent years, several studies have confirmed the clinical validity of the Oncotype DX breast cancer assay, not only as a way to predict recurrence but also as a tool for determining therapeutic benefit from adjuvant chemotherapy. Recently, Drs. Terry Mamounas, G. Thomas Budd, and Kathy Miller answered questions about the Oncotype DX assay that are particularly relevant to routine clinical practice. This expert dialog provides a useful update and essential clinical insights about how, why, and when community oncologists may want to incorporate this multi-gene assay into their care of breast cancer patients. In addition, sample case studies offer tangible examples of the practical application of Oncotype DX.

Subject

Adult; Female; Humans; Middle Aged; Genotype; Clinical Trials as Topic; *Gene Expression Profiling; *Breast Neoplasms/diagnosis/genetics/therapy; Breast Neoplasms/classification/*drug therapy/*genetics/surgery; Gene Expression Profiling/*methods; Polymerase Chain Reaction/methods; Tamoxifen/therapeutic use; Receptors; Antineoplastic Agents; Adjuvant; Chemotherapy; Adjuvant/methods; Estrogen/analysis; Hormonal/therapeutic use

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1–8

Issue

2

Volume

6

Citation

Mamounas Eleftherios P; Budd G Thomas; Miller Kathy D, “Incorporating the Oncotype DX breast cancer assay into community practice: an expert Q&A and case study sampling.,” NEOMED Bibliography Database, accessed June 20, 2021, https://neomed.omeka.net/items/show/5528.

Social Bookmarking