Tetrahydro-beta-carboline may produce its stimulus effects via 5HT1B receptors.

Title

Tetrahydro-beta-carboline may produce its stimulus effects via 5HT1B receptors.

Creator

Schechter M D

Publisher

Pharmacology, biochemistry, and behavior

Date

1987
1987-09

Description

To further clarify the role of 5-hydroxytryptamine (5HT) in the behavioral effects of tetrahydro-beta-carboline, male rats were trained to discriminate either 20 mg/kg THBC from its vehicle (n = 10) or 2.0 mg/kg fenfluramine from saline (n = 5). THBC was observed to produce fenfluramine-like effects in the fenfluramine-trained rats while fenfluramine produced THBC-like effects in the

Subject

Male; Animals; Rats; Serotonin/*metabolism; Piperazines/pharmacology; Discrimination Learning/drug effects; Serotonin Antagonists/pharmacology; Carbolines/*pharmacology; Metergoline/pharmacology; Inbred Strains; Receptors

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1–6

Issue

1

Volume

28

Citation

Schechter M D, “Tetrahydro-beta-carboline may produce its stimulus effects via 5HT1B receptors.,” NEOMED Bibliography Database, accessed February 24, 2021, https://neomed.omeka.net/items/show/5630.

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