The development of long-term potentiation in hippocampus and neocortex.
Title
The development of long-term potentiation in hippocampus and neocortex.
Creator
Teyler T J; Perkins A T 4th; Harris K M
Publisher
Neuropsychologia
Date
1989
1989
Description
The development of long-term potentiation (LTP), an enduring alteration in synaptic efficacy following afferent activation, was examined in CA1 hippocampus and primary visual cortex of rat. Both regions show little LTP prior to postnatal day 5, demonstrate a maximal potentiated response around postnatal day 15, and a subsequent decline to adult levels. These results are discussed with respect to the underlying mechanism of action and behavioral significance of these critical-period phenomena.
Subject
Female; Animals; Neurons/physiology; Rats; Electric Stimulation; *Synaptic Transmission; Aging/*physiology; Synapses/physiology; Hippocampus/*physiology; Cerebral Cortex/*physiology; Memory/*physiology; Evoked Potentials; Mental Recall/*physiology; Visual Cortex/physiology; Visual Pathways/physiology; Inbred Strains
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Citation
Teyler T J; Perkins A T 4th; Harris K M, “The development of long-term potentiation in hippocampus and neocortex.,” NEOMED Bibliography Database, accessed April 24, 2024, https://neomed.omeka.net/items/show/5667.