Polycystic kidney disease: detecting and managing extrarenal complications.

Title

Polycystic kidney disease: detecting and managing extrarenal complications.

Creator

Rutecki G W; Whittier F C

Publisher

Consultant (00107069)

Date

1995
1995-11

Description

Autosomal dominant polycystic kidney disease (ADPKD), the most common inherited disorder in this country, is more than just a renal disease. Major extrarenal sites are the cardiovascular system, liver, and GI tract. The most devastating cardiovascular abnormalities are occult CNS aneurysms; screening for such lesions is indicated in selected patients, including those with a family history of both ADPKD and berry aneurysms. Liver cysts are a common manifestation of ADPKD; hormonal factors may cause these cysts to enlarge during pregnancy. Colonic diverticula affect most patients with ADPKD; consider diverticular rupture in your differential diagnosis when a patient presents with abdominal pain or peritoneal signs. Instrumentation (eg, cystoscopy) increases the risk of urinary tract infection in ADPKD patients and should be avoided when possible.

Subject

Adult; Female; Antibiotics; Male; Middle Age; Hereditary Diseases; Kidney Diseases – Complications; Kidney Diseases – Diagnosis; Kidney Diseases – Therapy

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1667–1678

Issue

11

Volume

35

Citation

Rutecki G W; Whittier F C, “Polycystic kidney disease: detecting and managing extrarenal complications.,” NEOMED Bibliography Database, accessed May 8, 2021, https://neomed.omeka.net/items/show/6198.

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