Platelet-rich plasma for androgenetic alopecia: A review of the literature and proposed treatment protocol.

Title

Platelet-rich plasma for androgenetic alopecia: A review of the literature and proposed treatment protocol.

Creator

Stevens J; Khetarpal S

Publisher

International journal of women's dermatology

Date

2019
2019-02

Description

Androgenetic alopecia (AGA) is a common hair loss disorder caused by genetic and hormonal factors that are characterized by androgen-related progressive thinning of scalp hair in a defined pattern. By the age of 60 years, 45% of men and 35% of women develop AGA. Currently, U.S. Food and Drug Administration-approved treatments for AGA include oral finasteride and topical minoxidil. Due to the limited number of effective therapies for AGA, platelet-rich plasma (PRP) has become an effective alternative treatment. PRP is an autologous concentration of platelets in plasma with numerous growth factors that contribute to hair regeneration. The growth factors contained within the alpha granules of platelets act on stem cells in the bulge area of the hair follicles and stimulate the development of new follicles along with neovascularization. PRP has become a promising treatment modality for AGA. Although there have been several studies previously reported, a standard practice for PRP preparation and administration as well as a method to evaluate results have not been established. This literature review was conducted to evaluate the effectiveness of PRP for AGA and discuss the various treatment protocols that have been proposed.

Subject

alopecia; plasma; androgenetic; platelet; rich

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

46-51

Issue

1

Volume

5

NEOMED College

NEOMED College of Medicine

NEOMED Department

NEOMED Student Publications

Citation

Stevens J; Khetarpal S, “Platelet-rich plasma for androgenetic alopecia: A review of the literature and proposed treatment protocol.,” NEOMED Bibliography Database, accessed September 28, 2021, https://neomed.omeka.net/items/show/6275.

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