Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

Title

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

Creator

Szilagyi John T; Fussell Karma C; Wang Yun; Jan Yi-Hua; Mishin Vladimir; Richardson Jason R; Heck Diane E; Yang Shaojun; Aleksunes Lauren M; Laskin Debra L; Laskin Jeffrey D

Publisher

Toxicology and applied pharmacology

Date

2018
2018-11

Description

NADH cytochrome b5 reductase mediates electron transfer from NADH to cytochrome b5 utilizing flavin adenine dinucleotide as a redox cofactor. Reduced cytochrome b5 is an important cofactor in many metabolic reactions including cytochrome

Subject

Humans; Reactive Oxygen Species/metabolism; Oxidation-Reduction; Liver; *Reactive oxygen species; Kinetics; Recombinant Proteins/metabolism; Oxygen Consumption; Free Radicals/metabolism; Microsomes; *Cytochrome b5; *Free radicals; *Redox cycling; Benzoquinones/*metabolism; Cytochrome-B(5) Reductase/*metabolism; NADP/metabolism; Nitrofurantoin/*metabolism

URL Address

http://doi.org/10.1016/j.taap.2018.09.011

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

102-107

Volume

359

Citation

Szilagyi John T; Fussell Karma C; Wang Yun; Jan Yi-Hua; Mishin Vladimir; Richardson Jason R; Heck Diane E; Yang Shaojun; Aleksunes Lauren M; Laskin Debra L; Laskin Jeffrey D, “Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.,” NEOMED Bibliography Database, accessed January 25, 2025, https://neomed.omeka.net/items/show/6283.