Overview of Monogenic or Mendelian Forms of Hypertension
Title
Overview of Monogenic or Mendelian Forms of Hypertension
Creator
Raina Rupesh; Krishnappa Vinod; Das Abhijit; Amin Harshesh; Radhakrishnan Yeshwanter; Nair Nikhil R; Kusumi Kirsten
Publisher
Frontiers in Pediatrics
Date
2019
1905-07
Description
Monogenic or Mendelian forms of hypertension are described as a group of conditions characterized by insults to the normal regulation of blood pressure by the kidney and adrenal gland. These alterations stem from single mutations that lead to maladaptive overabsorption of electrolytes with fluid shift into the vasculature, and consequent hypertension. Knowledge of these various conditions is essential in diagnosing pediatric or early-onset adult hypertension as they directly affect treatment strategies. Precise diagnosis with specific treatment regimens aimed at the underlying physiologic derangement can restore normotension and prevent the severe sequelae of chronic hypertension.
Subject
aldosteronism; apparent mineralocorticoid excess; congenital adrenal hyperplasia; disease; familial; familial hyperaldosteronism; features; genes; Gordon syndrome; hyperaldosteronism; Liddle syndrome; Liddle syndrome; mineralocorticoid excess; monogenic hypertension; mutations; Pediatrics; prevalence; stroke; update
Identifier
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Rights
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Pages
263-263
Volume
7
Citation
Raina Rupesh; Krishnappa Vinod; Das Abhijit; Amin Harshesh; Radhakrishnan Yeshwanter; Nair Nikhil R; Kusumi Kirsten, “Overview of Monogenic or Mendelian Forms of Hypertension,” NEOMED Bibliography Database, accessed April 18, 2024, https://neomed.omeka.net/items/show/6523.