Overview of Monogenic or Mendelian Forms of Hypertension

Title

Overview of Monogenic or Mendelian Forms of Hypertension

Creator

Raina Rupesh; Krishnappa Vinod; Das Abhijit; Amin Harshesh; Radhakrishnan Yeshwanter; Nair Nikhil R; Kusumi Kirsten

Publisher

Frontiers in Pediatrics

Date

2019
1905-07

Description

Monogenic or Mendelian forms of hypertension are described as a group of conditions characterized by insults to the normal regulation of blood pressure by the kidney and adrenal gland. These alterations stem from single mutations that lead to maladaptive overabsorption of electrolytes with fluid shift into the vasculature, and consequent hypertension. Knowledge of these various conditions is essential in diagnosing pediatric or early-onset adult hypertension as they directly affect treatment strategies. Precise diagnosis with specific treatment regimens aimed at the underlying physiologic derangement can restore normotension and prevent the severe sequelae of chronic hypertension.

Subject

aldosteronism; apparent mineralocorticoid excess; congenital adrenal hyperplasia; disease; familial; familial hyperaldosteronism; features; genes; Gordon syndrome; hyperaldosteronism; Liddle syndrome; Liddle syndrome; mineralocorticoid excess; monogenic hypertension; mutations; Pediatrics; prevalence; stroke; update

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

263-263

Volume

7

Citation

Raina Rupesh; Krishnappa Vinod; Das Abhijit; Amin Harshesh; Radhakrishnan Yeshwanter; Nair Nikhil R; Kusumi Kirsten, “Overview of Monogenic or Mendelian Forms of Hypertension,” NEOMED Bibliography Database, accessed January 24, 2021, https://neomed.omeka.net/items/show/6523.

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