EROSIVE ARTHRITIS AND SPONDYLOARTHROPATHY IN OLD-WORLD PRIMATES

Title

EROSIVE ARTHRITIS AND SPONDYLOARTHROPATHY IN OLD-WORLD PRIMATES

Creator

Rothschild B M; Woods R J

Publisher

American Journal of Physical Anthropology

Date

1992
1992-07

Description

Presence of spine and sacroiliac involvement and the nature and distribution of the erosive lesions allow definitive diagnosis of spondyloarthropathy. Thus, spondyloarthropathy was identified in Theropithecus, Papio, Cercopithecus, Macaca, Colobus, Presbytis, and Hylobates. Only monarticular erosive disease was present in prosimians, precluding a diagnosis of spondyloarthropathy for that group. The distribution of erosive disease and axial joint involvement in 1,349 non-prosimian Old World primates is quite characteristic of that noted in human psoriatic arthritis. While Reiter's syndrome must also be considered, the histologic appearance of skin lesions in Macaca is characteristic of psoriasis. Evidence of spondyloarthropathy abounds in the literature of primate skeletal disease. Environmentally based contagions may be important in the pathophysiology of spondyloarthropathy. The wide geographic distribution of the phenomena in monkeys suggests a "panendemic," with limited individual susceptibility (compared to that noted in gorillas and chimpanzees). Identical occurrence of erosive arthritis/spondyloarthropathy in free-ranging and artificially restrained animals suggests that spondyloarthropathy can validly be studied in artificially restrained populations. This perspective should allow application of human therapeutic approaches to and perhaps improve the quality of life for artificially restrained afflicted individuals.

Subject

Anthropology; cercopithecus; colobus; disease; Evolutionary Biology; hla; hylobates; infection; macaca; papio; polyarthritis; presbytis; primate; psoriatic-arthritis; rhesus-monkey; rheumatoid-arthritis; skeletal pathology; theropithecus

Format

Journal Article

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

389-400

Issue

3

Volume

88

Citation

Rothschild B M; Woods R J, “EROSIVE ARTHRITIS AND SPONDYLOARTHROPATHY IN OLD-WORLD PRIMATES,” NEOMED Bibliography Database, accessed June 17, 2021, https://neomed.omeka.net/items/show/6927.

Social Bookmarking