Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia

Title

Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia

Creator

Selickman J; Paxos M; File T M; Seltzer R; Bonilla H

Publisher

Diagnostic Microbiology and Infectious Disease

Date

2010
2010-06

Description

The Streptococcus pneumoniae (SP) urinary antigen (UAg) test is a commonly used assay. The purpose cif this study was to evaluate the test's actual performance in the clinical setting and determine the effects of renal function, grade of bacteremia, and severity-of-illness scores on its outcome. Patients with pneumococcal bacteremia were retrospectively identified and stratified on the basis of glomerular filtration rates, number of positive blood cultures, and CURB-65 scores. Logistic regression was used to determine the effect that these 3 variables had on test outcomes. SP UAg testing was performed in 65 of 129 patients with pneumococcal bacteremia and was positive in 42 of 65 (64.5%). Impaired renal function was the only variable to have a significant effect on test outcome (P = 0.03). Test performance was less sensitive than prospective studies indicate. Patients with impaired renal function were significantly more likely to have positive UAg tests. (C) 2010 Elsevier Inc. All rights reserved.

Subject

adults; assay binax; bacteremia; community-acquired pneumonia; diagnosis; etiologic diagnosis; infections; Infectious Diseases; management; Microbiology; pneumococcal pneumonia; rapid diagnosis; severity; sputum culture; Streptococcus pneumoniae; Urinary antigen

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

129-133

Issue

2

Volume

67

Citation

Selickman J; Paxos M; File T M; Seltzer R; Bonilla H, “Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia,” NEOMED Bibliography Database, accessed December 1, 2021, https://neomed.omeka.net/items/show/7129.

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