A retrospective comparison of anesthetic agents in electroconvulsive therapy

Title

A retrospective comparison of anesthetic agents in electroconvulsive therapy

Creator

Swaim J C; Mansour M; Wydo S M; Moore J L

Publisher

Journal of Ect

Date

2006
2006-12

Description

A recent lack of availability of the anesthetic agent methohexital in the United States allowed for a naturalistic study of the efficacy and the adverse effects of alternatives. Methohexital, propofol, and thiopental were compared as anesthetic agents for electroconvulsive therapy in 95 patients treated during a 23-month period in a general public hospital. Missed seizures and arrhythmias were infrequently observed (< 4% for any agent). Methohexital was found significantly related to longer seizure durations in comparison with both other agents (P < 0.01). The use of propofol was associated with increased risk of missed seizure (8.9%) compared with methohexital (3.9%) and thiopental (3.2%). Propofol was also associated with higher doses of administered energy, with a statistically significant difference (P = 0.018) observed between propofol and thiopental. Although propofol required the greatest energy delivery, it was associated with the shortest seizure durations. Methohexital resulted in the longest seizure duration, and thiopental was associated with the least amount of energy delivery with an intermediate seizure length.

Subject

anesthetics; Behavioral Sciences; ect; electroconvulsive therapy; methohexital; propofol; Psychiatry; thiopental

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

243-246

Issue

4

Volume

22

Citation

Swaim J C; Mansour M; Wydo S M; Moore J L, “A retrospective comparison of anesthetic agents in electroconvulsive therapy,” NEOMED Bibliography Database, accessed March 7, 2021, https://neomed.omeka.net/items/show/7262.

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