Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila

Title

Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila

Creator

Tan J S; File T M; DiPersio J R; DiPersio L P; Hamor R; Saravolatz L D; Stout J E

Publisher

Clinical Infectious Diseases

Date

2001
2001-06

Description

We describe a patient with community-acquired pneumonia due to Legionella pneumophila serogroup 6. This patient was found to have bronchoalveolar carcinoma of the lung by means of cytologic testing in 1 of 2 bronchoalveolar lavage samples, but no lesions were visible on bronchoscopy. Despite intravenous administration of azithromycin to the patient, repeat culture and polymerase chain reaction showed persistence of Legionella; the isolates remained susceptible to azithromycin. The patient did not respond to 14 doses of daily intravenously administered azithromycin. The poor outcome may have been partially due to the suspected underlying lung malignancy, as shown by cytologic examination, and by a delay in seeking medical attention.

Subject

azithromycin; clarithromycin; erythromycin; hospitalized-patients; Immunology; Infectious Diseases; legionnaires-disease; macrolides; Microbiology; pcr; pharmacokinetics; time

Identifier

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1562-1566

Issue

11

Volume

32

Citation

Tan J S; File T M; DiPersio J R; DiPersio L P; Hamor R; Saravolatz L D; Stout J E, “Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila,” NEOMED Bibliography Database, accessed July 30, 2021, https://neomed.omeka.net/items/show/7277.

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