Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila
Title
Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila
Creator
Tan J S; File T M; DiPersio J R; DiPersio L P; Hamor R; Saravolatz L D; Stout J E
Publisher
Clinical Infectious Diseases
Date
2001
2001-06
Description
We describe a patient with community-acquired pneumonia due to Legionella pneumophila serogroup 6. This patient was found to have bronchoalveolar carcinoma of the lung by means of cytologic testing in 1 of 2 bronchoalveolar lavage samples, but no lesions were visible on bronchoscopy. Despite intravenous administration of azithromycin to the patient, repeat culture and polymerase chain reaction showed persistence of Legionella; the isolates remained susceptible to azithromycin. The patient did not respond to 14 doses of daily intravenously administered azithromycin. The poor outcome may have been partially due to the suspected underlying lung malignancy, as shown by cytologic examination, and by a delay in seeking medical attention.
Subject
azithromycin; clarithromycin; erythromycin; hospitalized-patients; Immunology; Infectious Diseases; legionnaires-disease; macrolides; Microbiology; pcr; pharmacokinetics; time
Identifier
Format
Journal Article
URL Address
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Rights
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Pages
1562-1566
Issue
11
Volume
32
Citation
Tan J S; File T M; DiPersio J R; DiPersio L P; Hamor R; Saravolatz L D; Stout J E, “Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila,” NEOMED Bibliography Database, accessed February 18, 2025, https://neomed.omeka.net/items/show/7277.