Antiphospholipids antibodies in a 12-month-old presenting with idiopathic thrombocytopenic purpura.

Antiphospholipids antibodies in a 12-month-old presenting with idiopathic thrombocytopenic purpura.

Nseir Bacel; Panicker Jyoti

Pediatric hematology and oncology

2008

2008-05

A 12-month-old Caucasian female with a history of recurrent ear infections presented to the emergency room with petechiae, severe thrombocytopenia (4000/microL), and abnormally prolonged activated partial thromboplastin time. Further autoantibody investigation detected antinuclear antibodies, anti-double-stranded DNA, and antiphospholipid antibodies. Platelet count, in response to intravenous immunoglobulin infusion, increased to more than 100 x 10(3) plt/microL. At 6-month follow-up, no positive autoantibodies were detected.

Antibodies; Antinuclear/blood/immunology; Antiphospholipid/*blood/immunology; Female; Humans; Idiopathic/*blood/*drug therapy/immunology; Immunoglobulins; Immunologic Factors/*administration & dosage; Infant; Intravenous/*administration & dosage; Purpura; Thrombocytopenic

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