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Regulation of aldo-keto reductases in human diseases.
The aldo-keto reductases (AKRs) are a superfamily of NAD(P)H-linked oxidoreductases, which reduce aldehydes and ketones to their respective primary…
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Change in Age of Diagnosis of Type 1 Diabetes Mellitus During the COVID-19 Era

BACKGROUND: Since the onset of COVID-19 in March 2020, anecdotally many pediatric endocrinologists felt there had been a shift in the age of…
Prevalence & Characteristics Of Treatment Resistant Depression Amongst Adolescent Youth In An Outpatient Psychiatric Setting

BACKGROUND: Adolescent depression is a prevalent psychiatric illness, with recent data showing that 16.4% of youth ages 12-17 in the United States…
A Case Report of an Atypical Presentation of a Humoral Immunodeficiency

BACKGROUND: 11-month-old vaccinated male directly admitted by his primary physician for multifocal pneumonia and pleural effusion in the setting of…
Exploring the Association between Adverse Childhood Experiences and Adolescent Suicidality

BACKGROUND: Approximately 64% of the US population has been exposed to at least one adverse childhood experience (ACE) before age 18.1,2 Youth exposed…
Ultrasound Guided Lumbar Puncture Simulation with Utilization of Infant Phantom Models to Improve First-Time Success Rate of Lumbar Punctures Performed in the Pediatric Emergency Department, a Quality Improvement Project

BACKGROUND: Lumbar punctures (LP) in infants are a common procedure in the emergency department. Research has shown that LPs performed without…
Advanced Ambulatory Curriculum

BACKGROUND: Pediatric residents require more in-depth training in general ambulatory pediatrics. Creating a curriculum to help address common…
Trends in Resource Utilization and Cost in Management of Well-appearing Febrile Infants 8 to 60 Days Old

INTRODUCTION: Over the past two decades, healthcare spending has increased, with a third of it on low-value care practices. Prior studies on resource…
Peeling Back the Layers: Leg Pain, Steroids and Truth in Disarray

BACKGROUND: 15-year-old female presented with bilateral severe thigh pain for 3 days. She described the pain as “squeezing,” unresponsive to…
A Comprehensive Study of Heart Disease in Ohio

This research study seeks to understand the risk factors and prevalence of cardiovascular disease in Ohio. A comprehensive investigation on heart…
Training Video on How Healthcare Providers Can Create a Welcoming Environment for Latino/a Patients

The Pew Research Center reported in 2022 that about half of Hispanics surveyed state that less access to quality medical care is a major reason for…