A thermodynamic and NMR investigation of 1-lyso-palmitoyllecithin/1,2-dipalmitoylphosphatidylethanol-amine/water system

Title

A thermodynamic and NMR investigation of 1-lyso-palmitoyllecithin/1,2-dipalmitoylphosphatidylethanol-amine/water system

Creator

Nicoletta F P; Checchetti A; Grasso D; Imbardelli D; LaRosa C; Westerman P; Chidichimo G

Publisher

Molecular Crystals and Liquid Crystals Science and Technology Section a-Molecular Crystals and Liquid Crystals

Date

1996
1996

Description

The effect of incorporation of 1-palmitoyl-sn-glycero-3-phosphocholine (PLPC) on the bilayer structures occurring in aqueous dispersions of 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) has been studied by phosphorus 31 nuclear magnetic resonance and calorimetric methods. The polymorphism of the system as a function of PLPC concentration has been defined. Experimental data allowed us to determine phase boundaries. Changes of molecular packing of the PLPC molecules in DPPE bilayers in the phase diagram are invoked to explain the experimental findings.

Subject

cholesterol; Crystallography; fusion; liposomal membranes; lysolecithin; temperature; vesicle

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

67-76

Volume

290

Citation

Nicoletta F P; Checchetti A; Grasso D; Imbardelli D; LaRosa C; Westerman P; Chidichimo G, “A thermodynamic and NMR investigation of 1-lyso-palmitoyllecithin/1,2-dipalmitoylphosphatidylethanol-amine/water system,” NEOMED Bibliography Database, accessed June 12, 2021, https://neomed.omeka.net/items/show/6639.

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