Staphylococcus aureus Bacteremia (SAB) With Associated S-aureus Bacteriuria (SABU) as a Predictor of Complications and Mortality

Title

Staphylococcus aureus Bacteremia (SAB) With Associated S-aureus Bacteriuria (SABU) as a Predictor of Complications and Mortality

Creator

Perez-Jorge E V; Burdette S D; Marked R J; Beam W B

Publisher

Journal of Hospital Medicine

Date

2010
2010-04

Description

BACKGROUND AND OBJECTIVES: Staphylococcus aureus (SA) bacteremia (SAB) is associated with a high rate of complications, most of which are related to hematogenous seeding into deep tissues or prosthetic material. SA bacteriuria (SABU) has been described in association with SAB, but has not been evaluated as a predictor for complicated bacteremia, which was the objective of our study. METHODS (DESIGN, SETTING, AND PATIENTS): We conducted a retrospective study of patients admitted to the hospital with SAB. The 118 patients included in the study were divided in 2 cohorts: a group with SABU and a group without SA in the urine. We followed the 2 cohorts for an average of 8 months and evaluated the differences in complications and mortality. RESULTS: SABU was found in 28 of 118 patients with SAB. Eighteen patients (64%) in this group had complications from the bacteremia, while in the group without SABU only 33% (30/90 patients) had complications (P = 0.004). The SABU group also had more deaths (32% vs. 14%; P = 0.036). CONCLUSIONS: In this population of hospitalized patients with SAB, the presence of SABU was associated with an increased risk of early complications, including septic shock, and with higher mortality. A routine urine culture in search of SABU may be a helpful tool for detection of those patients with SAB who are at increased risk of complications and death. Journal of Hospital Medicine 2010;5:208-211. (C) 2010 Society of Hospital Medicine.

Subject

adults; blood-stream infections; complications and mortality; complications from Staphylococcus aureus bacteremia; endocarditis; General & Internal Medicine; management; predictor of; Staphylococcus aureus bacteremia; Staphylococcus aureus bacteriuria; susceptibility; therapy; urinary-tract-infection

Identifier

Format

Journal Article

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

208-211

Issue

4

Volume

5

Citation

Perez-Jorge E V; Burdette S D; Marked R J; Beam W B, “Staphylococcus aureus Bacteremia (SAB) With Associated S-aureus Bacteriuria (SABU) as a Predictor of Complications and Mortality,” NEOMED Bibliography Database, accessed May 5, 2021, https://neomed.omeka.net/items/show/6757.

Social Bookmarking