Does pleural fluid pH change significantly at room temperature during the first hour following thoracentesis?

Title

Does pleural fluid pH change significantly at room temperature during the first hour following thoracentesis?

Creator

Sarodia B D; Goldstein L S; Laskowski D M; Mehta A C; Arroliga A C

Publisher

Chest

Date

2000
2000-04

Description

Background: Usually, pleural fluid (PF) pH is measured immediately following thoracentesis, and if there is any delay in the measurement, the PF sample is preserved on ice. Objective: To determine if PF pH changes significantly at room temperature during the first hour following thoracentesis, Design: Prospective, self-controlled, Setting: Tertiary care center. Patients: All patients undergoing thoracentesis. Measurements: The PF pH of a sample collected in an arterial blood gas syringe was measured immediately following thoracentesis by an arterial blood pH/gas analyzer. Additional measurements were made at 5, 15, 30, 45, and 60 min from the first pH measurement (pH0), maintained at room temperature. Results: For 28 PF samples, pH0 (mean +/- SD) was 7.351 +/- 0.158, and the GO-min pH (pH60) was 7.359 +/- 0.161. The mean difference between pH60 and pH0 was 0.008 +/- 0.026, which was not significant, either clinically or statistically (p = 0.13). Similarly, the interim pH values (for measures at 5, 15, 30, 45 min after pH0) were not significantly different from pH0 (mean differences, 0.002, 0.003, 0.005, and 0.004, respectively; p values, 0.51, 0.21, 0.06, and 0.22, respectively). Conclusions: The pleural fluid pH of a sample presented at room temperature does not change significantly during the first hour following thoracentesis. Hence, contrary to the common medical practice, there is no need to perform the pll measurement within minutes after thoracentesis and to preserve a pleural fluid sample on ice.

Subject

effusions; empyema; exudate; fluid; General & Internal Medicine; hydrogen ion concentration; pleural; pleural effusion; Respiratory System; specimen handling; temperature; time factor; transudate

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1043-1048

Issue

4

Volume

117

Citation

Sarodia B D; Goldstein L S; Laskowski D M; Mehta A C; Arroliga A C, “Does pleural fluid pH change significantly at room temperature during the first hour following thoracentesis?,” NEOMED Bibliography Database, accessed December 1, 2021, https://neomed.omeka.net/items/show/7001.

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