False-positive Uptake Of Fdg In Hepatic Sarcoidosis

False-positive Uptake Of Fdg In Hepatic Sarcoidosis

Guglielmi A N; Kim B Y; Bybel B; Slifkin N

Clinical Nuclear Medicine

2006

2006-03

Positron emission tomography (PET), with the use of F-18 fluorodeoxyglucose (FDG), has been shown to be useful in the evaluation of many tumors as a result of its high sensitivity and specificity. There are instances, however, in which false-positive FDG uptake can occur with inflammatory lesions or granulomatous diseases. In fact, false-positive mediastinal uptake in thoracic sarcoidosis has been well documented. We present a case of false-positive FDG uptake in the liver resulting from hepatic sarcoidosis. A 42-year-old, asymptomatic woman underwent a PET scan after a solitary pulmonary nodule was detected on a chest CT. The nodule in the left lower lobe on CT revealed no metabolic activity, but 2 lesions were found in the liver with SUVs in the range of 2.5 to 3.2. A subsequent MRI was not able to exclude malignancy. The liver lesions were surgically removed and found to be sarcoidosis.

FDG imaging; liver; Nuclear Medicine & Medical Imaging; positron-emission-tomography; Radiology; sarcoidosis

Journal Article or Conference Abstract Publication

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