Does birth weight affect neonatal body weight, growth, and physiology in an animal model?

Does birth weight affect neonatal body weight, growth, and physiology in an animal model?

Adjerid K; Mayerl CJ; Gould FDH; Edmonds CE; Stricklen BM; Bond LE; German RZ

PLOS One

2021

2021-02-16

Birth weight is an important predictor of neuromotor and physiological performance in early perinatal development of mammals [1–4]. Our knowledge of the impact of birth weight on growth and performance falls into two broad categories of research. First, studies have examined the relationship between birth weight and locomotor performance of neuromuscular systems within the first days of postnatal development. For example, Vanden Hole and colleagues specifically focused on detailed relationships of muscular development and force generation as a function of birth weight using newborn infant pigs [1, 3]. They found that lower birth weight in these mammalian infant resulted in a reduced chemical, neuromuscular, and biomechanical ability to generate force for locomotion [1–4]. However, the longitudinal effects of how low birth weight may impact systems outside of locomotion, including those related to feeding, is unknown.

Copyright: © 2021 Adjerid et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Journal Article

NEOMED College of Medicine

Department of Anatomy & Neurobiology

Jan to Aug list 2021