Thyrotoxicosis-Induced Cardiomyopathy With Systolic Dysfunction
Title
Thyrotoxicosis-Induced Cardiomyopathy With Systolic Dysfunction
Creator
Yusuf Khalil
Michael D Dube
Larry Woods
Date
2023
Description
Thyrotoxicosis-induced dilated cardiomyopathy is a rare but potentially life-threatening complication of thyrotoxicosis, with an incidence of <1%. This condition is characterized by a dilatation of the ventricular chamber and a decrease in cardiac contractility. Untreated, it can lead to irreversible changes in cardiac structure and function, including dilated ventricular chamber, a decrease in ejection fraction (EF), and an increased risk of atrial fibrillation. We present a case of a 39-year-old patient with a diagnosis of thyrotoxicosis-induced acute heart failure. A two-dimensional (2D) echocardiogram disclosed an ejection fraction of 36%, with diffuse mild dilation of the atria and ventricles with trace mitral and tricuspid regurgitation. The anti-thyroid-stimulating hormone (TSH) receptor was positive, and Grave's disease was diagnosed. The patient eventually returned to baseline functional status and could return to basic activities of daily living without limitations. The patient was encouraged to follow up with outpatient cardiology. Early diagnosis of cardiac involvement in patients with thyrotoxicosis is critical. Promptly delivered intensive treatment with the rapid achievement of euthyroid state can potentially reverse cardiac dysfunction and improve patient outcomes.
Source
Cureus
. 2023 Jan 20;15(1):e33988. doi: 10.7759/cureus.33988. eCollection 2023 Jan.
. 2023 Jan 20;15(1):e33988. doi: 10.7759/cureus.33988. eCollection 2023 Jan.
Language
English
URL
10.7759/cureus.33988
Citation
Yusuf Khalil, Michael D Dube , and Larry Woods , “Thyrotoxicosis-Induced Cardiomyopathy With Systolic Dysfunction,” NEOMED Bibliography Database, accessed May 1, 2024, https://neomed.omeka.net/items/show/12244.