New recommendations for the treatment of tuberculosis.

New recommendations for the treatment of tuberculosis.

Myers Joseph P

Current Opinion in Infectious Diseases

2005

2005-04

PURPOSE OF REVIEW: The aim of this article is to give practicing physicians a practical approach to the treatment of latent and active tuberculosis and to review newer recommendations and common problems encountered in the treatment of patients with tuberculosis. RECENT FINDINGS: Recently published literature documents the increased incidence of multidrug resistant strains of Mycobacterium tuberculosis, the importance of antituberculosis drug toxicities and drug-drug interactions, persistent problems in the correct interpretation of the tuberculin skin test and ongoing problems with treatment compliance and treatment completion. SUMMARY: This article provides a practical approach to the interpretation of the tuberculin skin test, the proper approach to the treatment of latent tuberculosis infection, and a structured approach to the treatment of presumed or documented active tuberculosis infection. Questions about tuberculosis that are often asked of infectious disease and pulmonary specialists are addressed in a very practical manner.

Adult; Antitubercular Agents – Administration and Dosage; Antitubercular Agents – Adverse Effects; Antitubercular Agents – Pharmacodynamics; Antitubercular Agents – Therapeutic Use; Antitubercular Agents/adverse effects/pharmacology/*therapeutic use; Bacterial; Chemical and Drug Induced Liver Injury; Child; Drug Resistance; Female; Hepatitis; HIV Infections – Complications; HIV Infections/complications; Humans; Infant; Microbial; Multiple; Practice Guidelines; Practice Guidelines as Topic; Preschool; Prescribing Patterns – Standards; Tuberculin Test; Tuberculosis – Drug Therapy; Tuberculosis – Epidemiology; Tuberculosis – Prevention and Control; Tuberculosis/*drug therapy/epidemiology/prevention & control; United States

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

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