Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.

Title

Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.

Creator

Arnold R; Johnson C; McNulty B; Gaisie G

Publisher

AJNR. American journal of neuroradiology

Date

2008
2008-04

Description

Exposure to cocaine in utero results in behavioral and neurodevelopmental abnormalities that persist into adulthood. Conventional MR imaging has generally failed to reveal the expected structural lesions to explain these clinical findings. We report a case of focal MR imaging signal-intensity changes in the substantia nigra, locus ceruleus, and other selected nerve tracts and nuclei in a child exposed prenatally to cocaine and other drugs. The patient also had dilated cardiomyopathy.

Subject

Female; Humans; Infant; Pregnancy; *Magnetic Resonance Imaging; Heroin/*adverse effects; Narcotics/*adverse effects; *Prenatal Exposure Delayed Effects; Child Development/drug effects; Cocaine/*adverse effects; Failure to Thrive/chemically induced/etiology; Substance-Related Disorders/*diagnosis/etiology; Substantia Nigra/drug effects/*pathology; Cardiomyopathy; Dilated/chemically induced/*diagnosis

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

828–829

Issue

4

Volume

29

Citation

Arnold R; Johnson C; McNulty B; Gaisie G, “Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.,” NEOMED Bibliography Database, accessed February 25, 2021, https://neomed.omeka.net/items/show/5118.

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