Nosocomial fungemia in a large community teaching hospital.

Nosocomial fungemia in a large community teaching hospital.

Harvey R L; Myers J P

Archives of Internal Medicine

1987

1987-12

This report reviews 48 episodes of hospital-acquired fungemia that occurred over a four-year period at a large community teaching hospital. The incidence of hospital-acquired fungemia increased eightfold during the study period. Candida albicans (58%), Candida tropicalis (25%), and Candida parapsilosis (15%) were the most common fungal pathogens isolated from blood cultures. Twenty-one patients (44%) had concomitant bacteremia. Intravascular catheters (100%), antibiotic administration (98%), urinary catheters (81%), surgical procedures (65%), parenteral alimentation (60%), and corticosteroid administration (54%) were the most common predisposing factors. The overall mortality rate was 75%. Hospitalization on the medical service, age greater than 60 years, and hospital stay less than 100 days were associated with a significantly increased mortality rate.

Adult; Humans; Middle Aged; Retrospective Studies; Teaching; Amphotericin B/therapeutic use; *Cross Infection; Candidiasis/complications/drug therapy/*etiology/mortality; Hematologic Diseases/complications/drug therapy/*etiology/mortality; Sepsis/complications; Community; *Hospitals

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2117–2120

12

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