Microfoci of avascular necrosis in sickle cell anemia: pathophysiology of the dot dash pattern.

Microfoci of avascular necrosis in sickle cell anemia: pathophysiology of the dot dash pattern.

Rothschild B M; Sebes J I; Hershkovitz I

Clinical and experimental rheumatology

1997

1997-12

OBJECTIVE: Definition of the nature of calcaneal "erosions" in sickle cell anemia. METHODS: Skeletons of individuals demonstrated to have had sickle cell anemia were examined for the presence of calcaneal surface discontinuity. RESULTS: Calcaneal and articular surface osseous microinfarction were identified macroscopically and confirmed radiologically by CT. CONCLUSIONS: This appears to be the first macroscopic identification of calcaneal and articular surface osseous microinfarction in sickle cell anemia and explains the osseous pathology that appears so unique to sickle cell anemia.

Humans; Male; Child; Necrosis; Tomography; Bone Diseases/diagnostic imaging/etiology/*pathology; Calcaneus/*blood supply/diagnostic imaging/*pathology; Infarction/etiology/*pathology; X-Ray Computed; Anemia; Sickle Cell/complications/*pathology

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663–666

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