Syringocystadenoma papilliferum of the male breast
Title
Syringocystadenoma papilliferum of the male breast
Creator
Nowak M; Pathan A; Fatteh S; Lopez J
Publisher
American Journal of Dermatopathology
Date
1998
1998-08
Description
A 39-year-old man presented with a 2-cm, mildly tender mass in the right breast of many years' duration. Microscopic examination showed a syringocystadenoma papilliferum. Because of its location in the breast, we studied the lesion for immunohistochemical markers for apocrine differentiation. Gross cystic disease fluid protein-15 (GCDFP-15) staining yielded negative results in the cystic luminal epithelial cells, whereas GCDFP-15 and lysozyme staining yielded strongly positive results in the epithelial cells of adjacent tubular apocrine glands. Focal strong lysozyme positivity was seen in the cystic luminal epithelial cells. These findings do not support apocrine differentiation in this case, despite its location in the breast, an organ rich in specialized apocrine (lactiferous) elands. To our knowledge, this represents the first reported case of syringocystadenoma papilliferum of the male breast. We present the clinical and pathologic features of this unusual case and a review of the literature.
Subject
apocrine; Breast; Dermatology; differentiation; eccrine differentiation; GCDFP-15; lysozyme; male; plasma cell infiltrate; syringocystadenoma papilliferum; tumors
Identifier
Format
Journal Article
URL Address
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Rights
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Pages
422-424
Issue
4
Volume
20
Citation
Nowak M; Pathan A; Fatteh S; Lopez J, “Syringocystadenoma papilliferum of the male breast,” NEOMED Bibliography Database, accessed April 27, 2024, https://neomed.omeka.net/items/show/6664.