Guidelines Of Care For The Management Of Basal Cell Carcinoma

Guidelines Of Care For The Management Of Basal Cell Carcinoma

Bichakjian C; Armstrong A; Baum C; Bordeaux J S; Brown M; Busam K J; Eisen D B; Iyengar V; Lober C; Margolis D J; Messina J; Miller A; Miller S; Mostow E; Mowad C; Nehal K; Schmitt-Burr K; Sekulic A; Storrs P; Teng J; Yu S; Huang C; Boyer K; Begolka W S; Alam M; Kim J Y S; Kozlow J H; Mittal B; Moyer J; Olencki T; Rodgers P

Journal of the American Academy of Dermatology

2018

2018-03

Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC. In the absence of a formal staging system, the best available stratification based on risk for recurrence is reviewed. With regard to treatment, we provide recommendations on treatment modalities along a broad therapeutic spectrum, ranging from topical agents and superficially destructive modalities to surgical techniques and systemic therapy. Finally, we review the available literature and provide recommendations on prevention and the most appropriate follow-up for patients in whom BCC has been diagnosed.

5-year follow-up; aminolevulinate photodynamic; basal cell carcinoma; biopsy; curettage; Dermatology; expectancy; fresh tissue technique; hedgehog pathway inhibitor; imiquimod 5-percent cream; limited life; metastasis; mohs micrographic surgery; nonmelanoma; open-label trial; phototherapy; radiotherapy; randomized controlled trial; skin-cancer; staging; Surgery; surveillance; therapy; topical therapy

Journal Article or Conference Abstract Publication

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