Browse Items (9409 total)

The Journal of Medical Sciences at NEOMED (JMS) is an online, student-led, peer-reviewed scholarly journal created to provide a platform for NEOMED students, faculty and affiliates to publish original research, opinion pieces, editorials, reviews,…

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer of the skin, with approximately 800,000 new cases diagnosed yearly in the US, and its incidence is continuing to increase. Although local cSCC is curable with conventional…

Background: The anterior cruciate ligament (ACL) is a supportive structure in the knee that provides resistance to internal tibial rotation and anterior tibial translation.1 ACL injuries are commonly seen in athletics and can lead to joint…

The purpose of this study was to describe the implementation of a virtual student-led research conference at a medical school in a rural area that focused on addressing disparities in medical education opportunities and ways to address disparities in…

The review aimed to examine the incidence, etiology, and time course of meningitis as a postoperative sequela of otologic surgeries. A systematic review was performed following PRISMA guidelines using the PubMed, Cochrane, and Web of Science…

In rural Nepal, neonatal hypothermia is a common complication due to a lack of proper infrastructure and resources at birthing centers. The purpose of this research study is to examine the common medical practices incorporated in Nepal for the…

Genetic testing for both somatic and germline mutations is a crucial component of the modern workup of cytopenia, myeloid neoplasms, and bone marrow failure syndromes. However, the specific genes tested in each clinical scenario are continually…

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Erythrodermic psoriasis is a rare, but serious subtype of psoriasis characterized by widespread erythema affecting over 75% of the total body surface area. It is a condition that may be mistaken for pathologies with similar clinical presentation,…

Background: Osteoporosis is characterized by a loss of bone mineral density (BMD) and bone mass, causing an increased risk of fractures associated with greater morbidity and mortality.1-4 Aged women are at an increased risk of osteoporosis due to…

Metabolic disorders like Leber Hereditary Optic Neuropathy (LHON), Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS), and Leigh Syndrome (LS) are severe, rare mitochondrial diseases causing perturbed…

Introduction: Positive Airway Pressure (PAP) therapy has been shown to reduce mortality risk in patients with obstructive sleep apnea (OSA), but its effectiveness across different subgroups remains unclear. This study aims to predict mortality based…

This project addresses workflow inefficiencies in the labor and delivery unit (L&D) at Summa Health, focusing on scheduling and resource distribution challenges that lead to significant delays in scheduled C-sections. These delays inconvenience…

Mechanisms underlying dysfunctional cognitive integration of social and emotional behavior following traumatic brain injury (TBI) are poorly understood. We aimed to develop a model to study longitudinal socioemotional behavior after TBI in rats.…

Alzheimer’s disease (AD), the leading cause of dementia and the sixth leading cause of death in the U.S. There is significant interest to develop therapies for the earliest stages of AD. β-amyloid (Aβ) plaque neuropathology is a hall mark of AD.…

Purpose: Obesity is a major contributor to chronic diseases like metabolic syndrome and cardiovascular conditions. In primary care, addressing weight management is crucial to mitigating these comorbidities. This sub analysis, part of a broader…

Focal nodular hyperplasia (FNH) of the liver is a benign hepatic lesion, commonly found in women in their third and fourth decades of life. FNH is hypothesized to arise from a vascular malformation resulting in a hyperplastic response. While FNH is a…

Osteoarthritis (OA) is the most common type of arthritis and a leading cause of disability. Currently, there is no cure for OA. More females develop OA compared to males. However, female mice were found to be protected from trauma-induced…

This case report presents a 30-year-old male patient with ESKD thought to be secondary to atrophic kidney and tubulointerstitial disease, who is currently on the kidney transplant list. His medical history is significant for insulin-dependent…

Integrins are cell-surface proteins that regulate cell growth and brain development. Research shows certain integrins (e.g. αVβ1 and αVβ5) are dysregulated in Alzheimer’s disease (AD), a tauopathy with limited therapeutic treatment. Irisin, a hormone…

Semaphorin 3F (SEMA3F), a class 3 semaphorin protein, is known for a plethora of bodily functions. Other class 3 semaphorins and their receptors have been found to regulate bone metabolism by dysregulating osteoclasts (OC) and/or osteoblast (OB)…

We present a case of a patient with multiple sclerosis misdiagnosed as ischemic stroke, resulting in repeated hospital admissions and delayed treatment. The atypical features of the case resulted in extensive workup consisting of multiple MRIs and a…

One of the many miracles of modern medicine is advances in survival among children with childhood cancer. Notably, children diagnosed with acute lymphoblastic leukemia (ALL) had a survival rate of 92% in the late 2010s compared to less than 60% in…

Background: Acute kidney injury (AKI) is seen in nearly 7% of hospital admissions and 30% of intensive care unit (ICU) admissions. It is associated with significant mortality and several major comorbidities including diabetes, sepsis, and heart…

Low-value care (LVC, services that offer minimal/no clinical benefit), is a focus area of health services research. Excess specialty referrals (XSR) from primary care is an example of LVC. This scoping review examined the drivers and consequences of…

This quality improvement project aims to determine if vaccination education increases vaccination rates among rural geriatric populations who are at a high risk for hospitalization as a result of pneumococcal pneumonia. The primary objective is to…

Background: Patients with head and neck cancer (HNC) face unique treatment-related challenges like dysphagia, dysgeusia, and appetite loss, leading to high rates of malnutrition. Often, patients are recommended placement of a percutaneous endoscopic…

Mammalian thermoregulation is an energetically expensive aspect of homeostasis. The body responds to temperature extremes through activities like sweating and shivering. Lemurs are well known for sunning and huddling to maintain body temperature when…

A 17-year-old female presents with recurrent epigastric pain following the diagnosis of median arcuate ligament syndrome (MALS) confirmed via ultrasound duplex and computed tomography angiography. Subsequent laparoscopic median arcuate ligament…

Background: Insulin autoimmune syndrome is a rare disorder characterized by anti-insulin antibodies which cause hyperinsulinemic hypoglycemia without any prior use of exogenous insulin. We report a case of a patient with hyperinsulinemic hypoglycemia…

Purpose: This article describes the clinical significance of the southern black widow spider (Latrodectus mactans). This includes discussing the spider's basic biology, the common symptoms of black widow spider bites, how healthcare professionals…

Health literacy, particularly in rural America, is a barrier that needs to be addressed in order to improve the overall quality of health amongst rural communities. Lower levels of health literacy are associated with increased hospitalization,…

Patients now have the ability to shop for physicians based on online reviews left on physician rating websites (PRW) by previous patients. In response to this, reputation management companies (RMCs) were created to manage online reviews for…

ATP13A2 is a P5 ATPase involved in lysosomal polyamine transport. Loss of function mutations are associated with multiple progressive neurodegenerative disorders including Parkinson’s disease. In many ATP13A2-related cases cognitive dysfunction…

Hypertension is a national crisis and can lead to cardiovascular issues such as heart failure, heart attack, heart disease, and stroke, as well as kidney disease, vision loss, and metabolic disorders. In rural communities, hypertension can be more…

Global longitudinal stress (GLS) is an advanced imaging technology that allows for the early detection of systolic dysfunction, which is crucial in preventing heart failure. Though GLS has seen limited use in mice models, recent studies have…

Hypertension is a growing concern worldwide, with increasing prevalence rates in both children and adults. Most cases of hypertension are multifactorial, with various genetic, environmental, socioeconomic, and lifestyle influences. However, monogenic…

Purpose: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a class of diabetes mellitus medications that have been a major focus of research over the past decade, and it’s not for their effects on lowering blood sugar. After their release to the…

Developing and implementing new policies for best practices across healthcare settings is a major challenge. Healthcare policies that affect older adults carry a weighted effect not only on patients, but also on caregivers, providers and the…

CT imaging of intervertebral discs (IVDs) is challenging due to the poor X-ray attenuation properties of the annulus fibrosus (AF) and nucleus pulposus (NP). IVD degeneration (IDD) is a leading cause of low back pain, contributing to substantial…