Browse Items (9303 total)

13NS_2.pdf
Non-bacterial thrombotic endocarditis (NBTE), or Marantic Endocarditis, is a rare and complex condition characterized by a spectrum of non-infectious lesions of the heart valves, most commonly the mitral and aortic valves. While the pathogenesis is…

9RW.pdf
Sexual assault is prevalent on U.S. academic campuses, with 13% of students experiencing rape or sexual assault,1 even with Title IX programming and support.2 We sought to understand health professional student experiences (e.g. assault/reporting…

10PT.pdf
Myxedema coma is a severe expression of longstanding uncontrolled hypothyroidism. Myxedema coma can be life-threatening and affects a multitude of organs, such as the heart, lungs, and kidneys. Patients typically present with altered mental status…

11ADfinal.pdf
The curry spice, turmeric, is used to provide color and flavor to food, as well as for its health benefits. Turmeric contains many polyphenolic compounds known as curcuminoids, with curcumin being the most prominent curcuminoid. In this perspective,…

2AB v5.pdf
Neck pain is an orthopedic condition for which physicians commonly refer to physical therapy (PT). Limited data exists on the extent of knowledge among referring physicians regarding PT clinical practice guideline (CPG) interventions. Our hypothesis…

1ABpublish.pdf
Paraneoplastic cerebellar degeneration (PCD) is a rare disorder characterized by progressively worsening cerebellar dysfunction associated with onconeural antibodies. Commonly, these antibodies are anti-neuronal nuclear antibody type 1 (ANNA-1, also…

14MO_Formatted_rev5.pdf
Cancer has consistently been a public health burden for many decades, responsible for high mortality and morbidity rates worldwide. Effective cancer diagnostic methods are crucial to improving patients' survival and timely implementation of…


Objective: The objectives of this study were to examine the prevalence of burnout, specify contributors to and protective factors against burnout, and gather suggestions to improve well-being in psychiatry Program Directors.

Methods: A survey…

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Pharmacy students wishing to maintain their breastfeeding relationship with their child while also excelling within a Doctor of Pharmacy program require important resources and a culture of support. This Commentary examines the challenges that…

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Purpose: Use of generation theory is pervasive within health professions education (HPE) literature, yet its application perpetuates unfounded generalizations that disadvantage learners. The objectives of this thematic analysis are first, to…

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Background: Capillary lymphatic venous malformations (CLVM) and associated syndromes, including Klippel-Trenaunay syndrome (KTS) and congenital lipomatous overgrowth, vascular malformation, epidermal nevi, skeletal, and spinal syndrome (CLOVES),…

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Background: Malignant peripheral nerve sheath tumors (MPNSTs) are clinically aggressive soft tissue sarcomas that can present as cutaneous or subcutaneous based tumors that are commonly associated with neurofibromatosis type 1. Historically, these…

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The utilization of the Papanicolaou (Pap) test and the human papillomavirus (HPV) vaccine has significantly decreased rates of cervical cancer and related mortality. Disparities in receiving these preventive screenings are scarcely studied in Muslim…

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Synucleinopathies like Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple systems atrophy (MSA), have the same pathologic feature of misfolded α-synuclein protein (α-syn) accumulation in the brain. PD patients who carry α-syn…

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Obesity has continued to emerge as a worldwide pandemic and has been associated with a significant increase in associated comorbidities. These include well-known conditions such as hypertension and diabetes, as well as lesser-known conditions such as…

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Background and aims: Rectovaginal fistula occurs in up to 10-20% of women with Crohn's disease, significantly affecting their quality of life. We sought to determine outcomes of single and repeat operative interventions.

Methods: A retrospective…

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Background: With increasing prevalence of opioid use disorders (OUDs) there is an urgent need for OUD trained front line primary care providers (PCPs) who can help improve patient adherence to addiction treatment. Unfortunately, most physicians…

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Background: It is unclear if protective childhood experiences (PCEs), like emotional support and economic stability, exert influence on adulthood adjustment. Prior research suggests PCEs can promote childhood resilience through increased social…

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It is a great honor to be invited to write a reflections article on my scientific journey and lifelong bile acid research for the Journal of Biological Chemistry, in which I am proud to have published 24 articles. I have also published 21 articles in…

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Homeostatic imbalance involving progressive stimulation of osteoclast (OC) differentiation and function will lead to an increased risk of fragility fractures. In this regard, we investigated gallium acetylacetonate (GaAcAc) as a possible treatment…

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Introduction: No guidelines exist for recommending return to driving. This study will examine time to brake (TTB) after lower extremity injuries versus in uninjured people. The potential effect of various types of lower extremity injuries on TTB…

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Ceramides (CERs) are key intermediate sphingolipids implicated in contributing to mitochondrial dysfunction and the development of multiple metabolic conditions. Despite the growing evidence of CER role in disease risk, kinetic methods to measure CER…

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Background: Pharmacists trained in veterinary pharmacy play important roles in community, hospital, academic, and industry settings. To date, there is limited available veterinary pharmacy education within Doctor of Pharmacy (PharmD) curricula. The…

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The pace of locomotor development is a critical component of lifetime evolutionary fitness. Developmental researchers often divide species into two broad categories based on functional competence at birth: precocial infants who can independently…

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Rotator cuff tear (RCT) is a common shoulder condition frequently treated with arthroscopic rotator cuff repair (ARCR) after conservative interventions have failed. Postoperative shoulder stiffness (POSS) is a common complication after ARCR. The…

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Objective: Left atrial volume index (LAVI) by echocardiography can be challenging and its accuracy is highly dependent on image quality. Cardiac computed tomography angiography (CTA) can overcome echocardiographic LAVI measurement challenges;…

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The purpose of this study was to examine the dynamic relationships between daily PTSD symptom severity (PTSS), cognitive and behavioral avoidance coping, and negative drinking consequences following recent injury. Participants consisted of 36 injury…

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Metabolic syndrome (MetS), characterized by hyperglycemia, obesity, and hyperlipidemia, can increase the risk of developing late-onset dementia. Recent studies in patients and mouse models suggest a putative link between hyperphosphorylated tau, a…

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Healthcare institutions are placing greater emphasis on equitable care. To accurately track and validate equity metrics, Akron Children's Hospital evaluated how key fields are collected, analyzed, and visualized throughout the organization.…

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The case presented is that of a young male with postanoxic brain injury secondary to cocaine overdose who began to exhibit choreiform movements of the left upper extremity. Traditional treatment options for chorea were unsuccessful, leading to the…

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Background and significance: Cardiac Amyloidosis (CA) is a manifestation of a systemic disorder resulting from the deposition of the transthyretin (TTR) in the myocardium, resulting in a myriad manifestations ranging from conduction defects to…

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Low oxygen bone marrow (BM) niches (~1%-4% low O2 ) provide critical signals for hematopoietic stem/progenitor cells (HSC/HSPCs). Our presented data are the first to investigate live, sorted HSC/HSPCs in their native low O2 conditions.…

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Modern tree sloths are one of few mammalian taxa for which quadrupedal suspension is obligatory. Sloth limb musculature is specialized for slow velocity, large force contractions that stabilize their body below branches and conserve energy during…

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Principal neurons (PNs) of the lateral superior olive nucleus (LSO) in the brainstem of mammals compare information between the two ears and enable sound localization on the horizontal plane. The classical view of the LSO is that it extracts ongoing…

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Facial feminization is a desire expressed by certain individuals who identify beyond the gender binary seeking to align their physical appearance and the gender with which they identify. Although there are many ways to achieve a more feminine facial…

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Background: The anterolateral thigh free flap is an option for repairing soft tissue defects of the distal lower extremity. This flap uses the descending branch of the lateral circumflex femoral (LCF) artery as the flap vessel. The recipient vessel…

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