Although a well-conducted randomized clinical trial did not show that azithromycin was non-inferior to doxycycline for the treatment of chlamydia, both treatments resulted in a high rate of cure (97% and 100%, respectively).
A randomized, placebo-controlled clinical trial from the Netherlands found that longer-term antibiotic therapy fo r Lyme disease did not improve health-related quality o f life compared to a standard course of treatment.