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Tags: LDLR protein

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Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice.

Objective- The objective of this study was to determine whether and how activation of farnesoid X receptor (FXR) by obeticholic acid (OCA), a clinical FXR agonist, modulates liver low-density lipoprotein receptor (LDLR) expression under…

Tags: 2018, Arteriosclerosis, thrombosis, and vascular biology, Dong Bin, Human, Kraemer Fredric B, LDL, LDLR protein, Liu Jingwen, Obeticholic acid, Receptors, RNA Stability, Singh Amar Bahadur, untranslated regions, Xu Yanyong, Zhang Yanqiao

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