Review of fluconazole treatment and prophylaxis for invasive candidiasis in neonates.
Title
Review of fluconazole treatment and prophylaxis for invasive candidiasis in neonates.
Creator
Hornik CD; Bondi DS; Greene NM; Cober MP; John B
Publisher
Journal Of Pediatric Pharmacology & Therapeutics
Date
2021
2021-02-15
Description
Invasive candidiasis accounts for approximately 10% of nosocomial infections in preterm infants, with an incidence of 1% to 4% among neonatal intensive care unit (NICU) admissions and a mortality as high as 20% to 30%. These outcomes warrant improved treatment and prevention strategies for infants at highest risk. The Infectious Diseases Society of America provides guidelines on antifungal medications for the prophylaxis and treatment of candidiasis in NICUs; however, there are still variations in practice on the use of fluconazole for prophylaxis and treatment of invasive candidiasis. This review provides specific information regarding fluconazole activity, pharmacokinetics, and a literature evaluation of dosing strategies and comparisons to other treatments in the neonatal population.
Identifier
Rights
Copyright. Pediatric Pharmacy Association. All rights reserved. For permissions, email: mhelms@pediatricpharmacy.org 2021.
Format
review
URL Address
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Pharmacy Practice
Update Year & Number
jan to Aug list 2021
Collection
Citation
Hornik CD; Bondi DS; Greene NM; Cober MP; John B, “Review of fluconazole treatment and prophylaxis for invasive candidiasis in neonates.,” NEOMED Bibliography Database, accessed May 5, 2024, https://neomed.omeka.net/items/show/11901.