Depletion of olfactory bulb norepinephrine by 6-OHDA disrupts chemical cue but not social recognition responses in male rats.

Depletion of olfactory bulb norepinephrine by 6-OHDA disrupts chemical cue but not social recognition responses in male rats.

Guan X; Blank J; Dluzen D

Brain research

1993

1993-09

In the present experiment, 6-OHDA was infused directly into the olfactory bulb (OB) to produce a localized neurotoxic lesion. Habituation/dishabituation behavioral tests were then conducted to measure recognition responses to chemical cues (urine as a stimulus) and to social stimuli (ovariectomized rat as a stimulus). Infusion of 6-OHDA resulted in a near complete depletion of

*Cues; *Social Perception; Animals; Choice Behavior/physiology; Female; Habituation; Hypothalamo-Hypophyseal System/physiology; Male; Norepinephrine/*metabolism; Olfactory Bulb/metabolism/*physiology; Ovariectomy; Ovary/physiology; Oxidopamine; Psychophysiologic/*physiology; Rats; Sprague-Dawley; Testis/physiology; Testosterone/blood; Zucker

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