Browse Items (1070 total)
- Tags: Animals
Tags: *Disease Susceptibility, *Signal Transduction, 2018, Animals, Carrier Proteins/chemistry/genetics/*metabolism, Gene Expression Regulation, Humans, Hussein Nazar J, International journal of molecular medicine, Mbimba Thomas, Najeed Ayesha, Protein Binding, Protein Interaction Domains and Motifs, Protein Transport, Safadi Fayez F, Structure-Activity Relationship
Tags: *Neuroinflammation, *Parkinson's disease, 1-Methyl-4-phenyl-1, 2, 2018, 3, 6-tetrahydropyridine/pharmacology, Analysis of Variance, Animals, Anti-Inflammatory Agents/*therapeutic use, Astrocyte, Astrocytes/*drug effects, Boyle Alexa M, Budge Kevin M, Case-Control Studies, CD44, Cells, Chemical, Cultured, Cytokines/genetics/metabolism, Databases, Female, Glial Fibrillary Acidic Protein/metabolism, GPNMB, Humans, Hyaluronan Receptors/*metabolism, Inflammation/*drug therapy/etiology, Journal of neuroinflammation, Male, Membrane Glycoproteins/*therapeutic use, Messenger/metabolism, Mice, Neal Matthew L, Neurotoxins/toxicity, Nitric Oxide/metabolism, Parkinson Disease/complications/*pathology, Reactive Oxygen Species/metabolism, Richardson Jason R, RNA, Safadi Fayez F, Signal Transduction/drug effects
A new zygodactylid species indicates the persistence of stem passerines into the early Oligocene in North America.
Tags: *Paleobiogeography, *Paleogene, *Passeriformes, *Phylogeny, *Zygodactylidae, 2019, Animals, BMC evolutionary biology, Body Size, Clarke Julia A, Department of Anatomy & Neurobiology, Extremities/anatomy & histology, Feathers/anatomy & histology, Fossils, Geography, Hieronymus Tobin L, NEOMED College of Graduate Studies, NEOMED College of Medicine, North America, Passeriformes/*classification, Skull/anatomy & histology, Species Specificity, Spine/anatomy & histology, Time Factors, Waugh David A
Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.
Tags: *angiogenesis, *cysteinyl leukotriene receptors, *endothelial cells, *metastasis, *tumor growth, 2019, Adapala Ravi K, Animals, Austen K Frank, Capillary Permeability/drug effects, Cyclohexanecarboxylic Acids/pharmacology, Department of Integrative Medical Sciences, Duah Ernest, Endothelial Cells/*drug effects, Experimental, Gene Knockout Techniques, Inbred C57BL, Kanaoka Yoshihide, Keshamouni Venkateshwar G, Kondeti Vinay, Leukotriene Antagonists/pharmacology, Leukotriene/drug effects/*metabolism, Lung Neoplasms/drug therapy, Male, Mice, NEOMED College of Medicine, Neoplasm Metastasis/drug therapy, Neoplasm Transplantation, Neoplasms, Neovascularization, Paruchuri Sailaja, Pathologic/*chemically induced/drug therapy, Phthalic Acids/pharmacology, Proceedings of the National Academy of Sciences of the United States of America, Receptors, Teegala Lakshminarayan Reddy, Thodeti Charles K
Tags: *Axonopathy, *axons, *neurodegeneration, *neurofilament, *node of Ranvier, *superior colliculus, 2018, Action Potentials, Animals, Axons/pathology, Crish S D, Cytoskeleton/pathology, Dengler-Crish Christine M, Department of Pharmaceutical Sciences, Female, Glaucoma/metabolism/pathology/*physiopathology, Inbred C57BL, Male, Meier J, Mice, NEOMED College of Pharmacy, Neuroscience, Optic Nerve/metabolism/pathology, Plyler E S, Ranvier's Nodes/*physiology/ultrastructure, Smith M A, Transgenic, Visual Pathways/metabolism/*physiopathology/ultrastructure, Voltage-Gated Sodium Channels/metabolism
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Parkinson's disease, *Sensorimotor function, 2018, Adenosine Triphosphatases/genetics/*metabolism, Aga Diana S, alpha-Synuclein/metabolism, Animal, Animals, Behavior, Brain/*drug effects/*metabolism, Department of Pharmaceutical Sciences, Ekhator Osunde R, Female, Fleming Sheila M, Holden John G, Inbred C57BL, Karkare Swagata, Knockout, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Male, Manganese/metabolism/*toxicity, Membrane Proteins/genetics/*metabolism, Mice, Motor Activity, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
Tags: *Atherosclerosis, *Farnesoid X receptor, *NAFLD, *Obesity, *TGR5, 2018, Adorini Luciano, Animals, Bile Acids and Salts/pharmacology/*therapeutic use, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Diet, G-Protein-Coupled/*agonists, Hep G2 Cells, High-Fat/adverse effects, Humans, Hypercholesterolemia/*drug therapy/etiology/metabolism, Inbred C57BL, Jadhav Kavita, Kasumov Takhar, Lee Yoon Kwang, Li Yuanyuan, Male, Mice, Molecular metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*drug therapy/etiology/metabolism, Obesity/*drug therapy/etiology/metabolism, Receptors, Xu Jiesi, Xu Yang, Xu Yanyong, Yin Liya, Zhang Yanqiao, Zhu Yingdong
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.
Tags: 2018, Administration, Alboslemy Talib, Animal, Animals, Cell Communication/*physiology, Cell Differentiation, Cells, Cultured, Cutaneous, Diabetes Mellitus, Disease Models, Eye Proteins/administration & dosage/genetics/*physiology, Humans, Inbred C57BL, Kim Min-Ho, Macrophages/*physiology, Male, Membrane Glycoproteins/administration & dosage/genetics/*physiology, Mesenchymal Stem Cells/*physiology, Mice, Recombinant Proteins/administration & dosage/genetics/metabolism, Safadi Fayez, Skin/*injuries/metabolism, The Journal of investigative dermatology, Type 2/complications/pathology, Wound Healing/*physiology, Yu Bing
Tags: *gp91(phox), *Microglia, *MPTP, *Na(v)1.6, *Neuroinflammation, *Parkinson's disease, *TNF-alpha, *Voltage-gated sodium channels, *Zonisamide, 2018, Aged, Animals, Antiparkinson Agents/*pharmacology, Experimental neurology, Female, Gearing Marla, Hossain Muhammad M, Humans, Inbred C57BL, Inflammation/metabolism, Male, Mice, Microglia/drug effects/*metabolism, NAV1.6 Voltage-Gated Sodium Channel/*biosynthesis, Neuroprotective Agents/pharmacology, Parkinsonian Disorders/*metabolism/pathology, Reuhl Kenneth, Richardson Jason R, Weig Blair, Wu Long-Jun, Zonisamide/*pharmacology
Acute exposure to a glyphosate-containing herbicide formulation inhibits Complex II and increases hydrogen peroxide in the model organism Caenorhabditis elegans.
Tags: *hydrogen peroxide, *Reactive oxygen species, 2019, Adenosine Triphosphate/metabolism, Animals, Bailey Denise C, Burchfield Shelbie L, C. elegans, Caenorhabditis elegans/*drug effects/metabolism, Denney Rachel D, Department of Pharmaceutical Sciences, Electron Transport Complex II/*antagonists & inhibitors/metabolism, Environmental toxicology and pharmacology, Fitsanakis Vanessa A, Glycine/*analogs & derivatives/toxicity, Glyphosate, Herbicides/*toxicity, Mitochondrial inhibition, Negga Rekek, NEOMED College of Pharmacy, Oxygen Consumption, Reactive Oxygen Species/metabolism, Todt Callie E
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.
Tags: *Signal Transduction, 2018, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cytoplasmic and Nuclear/*antagonists & inhibitors/pharmacology, Department of Integrative Medical Sciences, Disease Models, Ferrell Jessica M, G-Protein-Coupled/*metabolism, Gastrointestinal Microbiome/*drug effects, Glucagon-Like Peptide 1/metabolism, Gonzalez Frank J, GTP-Binding Proteins/*metabolism, Hepatology (Baltimore, Md.), Inbred C57BL, Krausz Kristopher W, Lipid Metabolism, Male, Mice, NEOMED College of Medicine, Nichols Robert G, Pathak Preeti, Patterson Andrew D, Random Allocation, Receptors, Sensitivity and Specificity, Xie Cen
Tags: 1997, Adult, Aged, Animals, Antifungal Agents – Therapeutic Use, Antifungal Agents/*therapeutic use, Brodell R T, Cattle, Child, Dermatomycoses – Diagnosis, Dermatomycoses – Drug Therapy, Dermatomycoses – Pathology, Dermatomycoses/*diagnosis/*drug therapy/pathology, Diagnosis, Differential, Elewski B, Female, Humans, Male, Middle Age, Middle Aged, Nail Diseases – Diagnosis, Nail Diseases – Etiology, Nail Diseases/diagnosis/etiology, Postgraduate medicine, Psoriasis – Diagnosis, Psoriasis/diagnosis, Tinea – Diagnosis, Tinea – Drug Therapy, Tinea – Etiology, Tinea/*diagnosis/*drug therapy/etiology
Tags: 1997, Animals, Archives of internal medicine, Bacterial Infections, Bacterial Infections – Transmission, Cats, Disease Vectors, Dogs, Ectoparasitic Infestations, Ectoparasitic Infestations – Transmission, Helminthiasis – Transmission, Protozoan Infections – Transmission, Tan J S, Zoonoses – Transmission
Tags: 2008, Animal Studies, Animals, Central Nervous System Stimulants – Pharmacodynamics, Central Nervous System Stimulants – Pharmacokinetics, Depression – Drug Therapy, Dluzen D E, Female, Gender Identity, Gender medicine, Liu B, Male, Methamphetamine – Pharmacodynamics, Methamphetamine – Pharmacokinetics, Reproduction, Sex Factors, Substance Use Disorders
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Antineoplastic Agents – Therapeutic Use, Apoptosis – Drug Effects, Biochemical Phenomena, Bishayee A, Cell Physiology – Drug Effects, Chemoprevention, Darvesh A S, Department of Pharmaceutical Sciences, Folkesson H G, Háznagy-Radnai E, Hohmann J, Journal of Nutritional Biochemistry, Liver – Pathology, Liver Neoplasms – Chemically Induced, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms – Prevention and Control, Male, Mbimba T, NEOMED College of Pharmacy, Nitrosamines, Phenobarbital, Plant Extracts – Therapeutic Use, Plants, Preventive Cardiovascular Nurses Association, Proteins – Metabolism, Rats, Sipos P, Thoppil R J
On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Tags: *DNA-Binding Proteins, 2002, alpha-Fetoproteins/genetics/*physiology, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Biochimica et biophysica acta, Cattle, Chiang John Y L, Cytochrome P-450 Enzyme System/*genetics, Department of Integrative Medical Sciences, DNA, Eggertsen Gosta, Enzymologic/*drug effects/physiology, Gene Expression Regulation, Genetic, Genetic/*drug effects, Hepatocyte Nuclear Factor 4, Messenger/genetics, NEOMED College of Medicine, Phosphoproteins/genetics/*physiology, Promoter Regions, Rats, RNA, Sprague-Dawley, Steroid 12-alpha-Hydroxylase, Steroid Hydroxylases/*genetics, Transcription, Transcription Factors/genetics/*physiology, Yang Yizeng, Zhang Ming
A neurochemical heterogeneity of the rat striatum as measured by in vivo electrochemistry and microdialysis.
Tags: 1990, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Amphetamines/*pharmacology, Animals, Brain research, Corpus Striatum/*metabolism, Dopamine D2, Dopamine/*metabolism, Dopamine/drug effects, Electrochemistry, Inbred Strains, Male, Pehek E A, Rats, Receptors, Sulpiride/*pharmacology, Yamamoto B K
Tags: 1988, 3, 4-Dihydroxyphenylacetic Acid/metabolism, 4-methylenedioxyamphetamine, 4-Methylenedioxyamphetamine/analogs & derivatives/*pharmacology, Amphetamines/*pharmacology, Animals, Brain/drug effects/metabolism, Caudate Nucleus/drug effects/metabolism, Consciousness, Dopamine/*metabolism, European journal of pharmacology, Inbred Strains, Male, N-Methyl-3, Nucleus Accumbens/drug effects/metabolism, Rats, Spanos L J, Yamamoto B K
Tags: 1999, Animals, Base Sequence, Blotting, Cell Line, Chiang J Y, Chromosome Mapping, Cloning, Codon, Complementary/biosynthesis/*isolation & purification, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 7, Department of Integrative Medical Sciences, DNA, Genetic, Genetic/genetics, Humans, Hydroxycholesterols/metabolism, Initiator, Javitt N B, Journal of lipid research, Luciferases/genetics, Martin K O, Mice, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Northern, Nucleic Acid, Promoter Regions, Regulatory Sequences, Steroid Hydroxylases/*genetics/metabolism, Transcription, Transfection, Wu Z
Sharing of sensory terminals between the dynamic bag1 and static bag2 fibers in the rat muscle spindle.
Tags: *Nerve Regeneration, 1989, Adenosine Triphosphatases/analysis, Afferent/enzymology/metabolism/*physiology, Animals, Cell Differentiation, Cui F, Female, Graft Survival, Histochemistry, Histocytochemistry, Inbred Strains, Kucera J, Motor Neurons/enzymology/metabolism/*physiology, Muscle Spindles/enzymology/*physiology, Muscles/transplantation, Nerve Fibers/enzymology/physiology, Neurons, Rats, Staffeld C G, Walro J M
Changes in instrumentally and classically conditioned limb-flexion responses following inferior olivary lesions and olivocerebellar tractotomy in the cat.
Tags: *Conditioning, *Conditioning (Psychology), *Movement, 1990, Animals, Bogdanski R, Brain/anatomy & histology, Cats, Cerebellum/*physiology, Chopko B, Christie D, Classical, Electric Stimulation, Forelimb, Male, Olivary Nucleus/*physiology, Reference Values, The Journal of neuroscience : the official journal of the Society for Neuroscience, Time Factors, Voneida T J
A method for calculating current source density (CSD) analysis without resorting to recording sites outside the sampling volume.
Tags: *Synaptic Transmission, 1989, Aging/*physiology, Animals, Cerebral Cortex/*physiology, Electric Stimulation, Evoked Potentials, Female, Harris K M, Hippocampus/*physiology, Inbred Strains, Memory/*physiology, Mental Recall/*physiology, Neurons/physiology, Neuropsychologia, Perkins A T 4th, Rats, Synapses/physiology, Teyler T J, Visual Cortex/physiology, Visual Pathways/physiology
Expression of hepatic microsomal cholesterol 7 alpha-hydroxylase activity in lean and obese Zucker rats.
Tags: 1988, Animals, Biochemical and biophysical research communications, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*metabolism, Cholestyramine Resin/pharmacology, Department of Integrative Medical Sciences, Female, Finkelstein J A, Liver/*enzymology, Male, Microsomes, NEOMED College of Medicine, Obesity/*metabolism, Rats, Sex Factors, Species Specificity, Steroid Hydroxylases/*metabolism, Tang P M, Zucker/metabolism
Tags: 1990, Animals, Brain Stem/*cytology, Cerebral Cortex/*cytology, Experimental brain research, Female, Horseradish Peroxidase, Immunohistochemistry, Inbred Strains, Male, Newman D B, Phytohemagglutinins, Rats, Stuesse S L, Visual Pathways/*anatomy & histology, Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate, Wheat Germ Agglutinins
Distribution of tyrosine hydroxylase- and serotonin-immunoreactive cells in the central nervous system of the thornback guitarfish, Platyrhinoidis triseriata.
Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7alpha-hydroxylase gene (CYP7A).
Tags: *Gene Expression Regulation, *Receptors, 1997, Animals, Chiang J Y, Chickens, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Circadian Rhythm, COUP Transcription Factor I, COUP Transcription Factor II, COUP Transcription Factors, Crestani M, Department of Integrative Medical Sciences, DNA-Binding Proteins/*metabolism, Electrophoresis, Enzymologic, Genetic, Glucocorticoid/*genetics, Models, Molecular, NEOMED College of Medicine, Nuclear Proteins/*metabolism, Polyacrylamide Gel, Promoter Regions, Rats, Receptors, Recombinant Proteins/genetics/metabolism, Retinoic Acid/*metabolism, Retinoid X Receptors, Steroid, Stroup D, The Journal of biological chemistry, Transcription Factors/*metabolism
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
Tags: *Receptors, *Transcription, 2000, Animals, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, COUP Transcription Factor II, COUP Transcription Factors, Cultured, Department of Integrative Medical Sciences, DNA Primers, DNA-Binding Proteins/*metabolism, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Luciferases/genetics, Mutation, NEOMED College of Medicine, Phosphoproteins/*metabolism, Promoter Regions, Rats, Recombinant Proteins/metabolism, Reporter, Sprague-Dawley, Steroid, Stroup D, Transcription Factors/*metabolism, Tumor Cells
A comparative analysis of monoaminergic involvement in the spinal antinociceptive action of DAMPGO and DPDPE.
Tags: 1989, 5)-, Ala(2)-MePhe(4)-Gly(5)-, Amines – Physiology, Anesthetics – Pharmacodynamics, Anesthetics/*pharmacology, Animals, Biogenic Monoamines/*physiology, Cell Surface – Drug Effects, Cell Surface – Physiology, Crisp T, D-Penicillamine (2, Dose-Response Relationship, Drug, Enkephalin, Enkephalins, Enkephalins – Pharmacodynamics, Enkephalins/*pharmacology, Inbred Strains, Injections, Intraspinal, Male, Naloxone – Pharmacodynamics, Naloxone/pharmacology, Opioid/drug effects/*physiology, Pain, Pain – Metabolism, Pain/*metabolism, Rats, Receptors, Spanos L J, Spinal, Spinal Cord – Drug Effects, Spinal Cord – Metabolism, Spinal Cord – Physiopathology, Spinal Cord/drug effects/metabolism/*physiopathology, Stafinsky J L
Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat.
Tags: 1989, 3, 4-methylenedioxyamphetamine, 4-Methylenedioxyamphetamine/analogs & derivatives/*pharmacology, Amphetamines/*pharmacology, Animal/*drug effects, Animals, Behavior, Designer Drugs/*pharmacology, Dose-Response Relationship, Drug, Inbred Strains, Male, Motor Activity/*drug effects, N-Methyl-3, Pharmacology, biochemistry, and behavior, Rats, Receptors, Serotonin/*drug effects, Spanos L J, Time Factors, Yamamoto B K
Tags: 1988, Animals, Conditioning, Cues, Discrimination (Psychology)/*physiology, Dopamine/drug effects/*physiology, Dose-Response Relationship, Drug, Ethanol/*pharmacology, Inbred Strains, Male, Operant/physiology, Pharmacology, biochemistry, and behavior, Rats, Receptors, Schechter M D, Serotonin/drug effects/*physiology, Signs S A