Browse Items (17 total)
- Tags: 2
Methamphetamine-induced Loss Of Striatal Dopamine Innervation In Bdnf Heterozygote Mice Does Not Further Reduce D-3 Receptor Concentrations
Tags: 1-Methyl-4-phenyl-1, 2, 2004, 3, 6-tetrahydropyridine mptp, Behavioral, caudate putamen, differential regulation, Dluzen D E, Dopamine, haloperidol treatment, Journal Article or Conference Abstract Publication, Joyce J N, Kucera J, monkey, motor neurons, mutant mice, Neurosciences & Neurology, neurotrophic factor, nucleus accumbens, Osredkar T, parkinsons-disease, Renish L, Sensitization, striatum, substantia-nigra, synapse, transporter, Tyrosine hydroxylase, Walro J M
2.5d Constructs For Characterizing Phase Separated Polymer Blend Surface Morphology In Tissue Engineering Scaffolds
Tags: 2, 2013, 3d, 5D scaffolds, Adapala R K, cell-shape, differentiation, Engineering, Journal of Biomedical Materials Research Part A, Karim A, L-lactide), Marszalek J E, Materials Science, mechanical-properties, Murthy A, poly(D, poly(e-caprolactone), polymer blends, Porosity, proliferation, Simon C G, Thodeti C, topography
Neuroprotective Role Of Estrogen Upon Methamphetamine And Related Neurotoxins Within The Nigrostriatal Dopaminergic System
Tags: 1-Methyl-4-phenyl-1, 1-methyl-4-phenylpyridinium ion, 2, 2000, 3, 6-tetrahydropyridine, c57/b1 mice, Dluzen D E, estradiol, lipid-peroxidation, McDermott J L, mptp-induced neurotoxicity, Neurobiological Mechanisms of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines, parkinsons-disease, release, sexual differences, striatum
Modulatory Effects Of Testosterone On 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurotoxicity
Tags: 1-Methyl-4-phenyl-1, 1994, 2, 3, 6-tetrahydropyridine, aged rats, amphetamine, Biochemistry & Molecular Biology, castrated male-rats, corpus striatum, Dluzen D, Dopamine, dopamine release invitro, estrogen-treatment, Jain R, Journal of neurochemistry, l-dopa, Liu B J, Mice, Neurosciences & Neurology, parkinsons-disease, rotational behavior, sex-differences, steroid-hormones, Testosterone
Sex differences in methamphetamine toxicity in mice: Effect on brain dopamine signaling pathways
Tags: 1-Methyl-4-phenyl-1, 2, 2011, 3, 6-tetrahydropyridine mice, activation, Akt, Bourque M, cd-1, cell-death, Di Paolo T, Dluzen D E, Dopamine, element-binding protein, Endocrinology & Metabolism, evoked striatal dopamine, Induced, Journal Article or Conference Abstract Publication, Kinase, Liu B, Methamphetamine, Mice, Neurosciences & Neurology, Neurotoxicity, Psychiatry, Psychoneuroendocrinology, rat striatum, Sex difference, striatum, transporter function
Signaling pathways mediating the neuroprotective effects of sex steroids and SERMs in Parkinson's disease
Tags: 1-Methyl-4-phenyl-1, 2, 2012, 3, 6-tetrahydropyridine, Akt, Bourque M, Di Paolo T, Dluzen D E, Endocrinology & Metabolism, er-alpha, ERK, estradiol, estrogen, estrogen-receptor-alpha, Frontiers in Neuroendocrinology, gender-differences, growth-factor-i, Journal Article or Conference Abstract Publication, Mice, MPTP, nervous-system, Neuroprotection, Neurosciences & Neurology, plasma-membrane, protein-coupled receptor-30, rat-brain, Receptor, selective estrogen, SERMs, Signaling, striatum, SUBSTANTIA nigra
POSSIBLE SEROTONERGIC AND DOPAMINERGIC MEDIATION OF THE N-ETHYL-3,4-METHYLENEDIOXYAMPHETAMINE DISCRIMINATIVE STIMULUS
Tags: (3, 1991, 2, 3, 4-methylenedioxyamphetamine), 4-methylenedioxymethamphetamine), 4-tetrahydro-beta-carboline, 5-ht (5-hydroxytryptamine, 6-methoxy-1, amphetamine, Boja J W, Dopamine, drug discrimination, European journal of pharmacology, fenfluramine, Journal Article or Conference Abstract Publication, mde, mde (n-ethyl-3, mdma, p-chlorophenylalanine, Pharmacology & Pharmacy, pigeons, quipazine, rat, saline, Schechter M D, serotonin, tfmpp
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
Tags: 1-Methyl-4-phenyl-1, 2, 2002, 3, 6-tetrahydropyridine mptp, adult brain, Biotechnology & Applied Microbiology, central-nervous-system, dopaminergic, gene-transfer, growth factor, Journal Article, juvenile neocortex, Lynch W P, mouse-brain, Nature Biotechnology, Neurotoxicity, Ourednik J, Ourednik V, parkinsons-disease, Replacement, Schachner M, Snyder E Y
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.
Tags: *Neuroinflammation, *Parkinson's disease, 1-Methyl-4-phenyl-1, 2, 2018, 3, 6-tetrahydropyridine/pharmacology, Analysis of Variance, Animals, Anti-Inflammatory Agents/*therapeutic use, Astrocyte, Astrocytes/*drug effects, Boyle Alexa M, Budge Kevin M, Case-Control Studies, CD44, Cells, Chemical, Cultured, Cytokines/genetics/metabolism, Databases, Female, Glial Fibrillary Acidic Protein/metabolism, GPNMB, Humans, Hyaluronan Receptors/*metabolism, Inflammation/*drug therapy/etiology, Journal of neuroinflammation, Male, Membrane Glycoproteins/*therapeutic use, Messenger/metabolism, Mice, Neal Matthew L, Neurotoxins/toxicity, Nitric Oxide/metabolism, Parkinson Disease/complications/*pathology, Reactive Oxygen Species/metabolism, Richardson Jason R, RNA, Safadi Fayez F, Signal Transduction/drug effects
Modulatory effects of testosterone on
Tags: *MPTP Poisoning, 1-Methyl-4-phenyl-1, 1994, 2, 3, 6-tetrahydropyridine/antagonists & inhibitors, Animals, Corpus Striatum/drug effects/*metabolism, Dluzen D, Dopamine/*metabolism, Drug Implants, Inbred C57BL, Inbred Strains, Jain R, Journal of neurochemistry, Levodopa/pharmacology, Liu B, Male, Mice, Neurotoxins/antagonists & inhibitors/*toxicity, Orchiectomy, Parkinson Disease, Reference Values, Secondary/chemically induced/*physiopathology, Species Specificity, Testosterone/administration & dosage/*pharmacology
The effects of intranasal infusion of
Tags: 1-Methyl-4-phenyl-1, 1996, 2, 3, 6-tetrahydropyridine/administration & dosage/*pharmacology, Administration, Animals, Brain research, Catecholamines/*metabolism, Corpus Striatum/drug effects/*metabolism, Department of Internal Medicine, Dluzen D E, Dopamine Agents/administration & dosage/*pharmacology, Dopamine/metabolism, Inbred C57BL, Injections, Intranasal, Intraperitoneal, Kefalas G, Male, Mice, NEOMED College of Medicine, Norepinephrine/metabolism, Olfactory Bulb/drug effects/*metabolism
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains.
Tags: *QTL, *Recombinant inbred mice, *Sex Characteristics, *Sex differences, 1-Methyl-4-phenyl-1, 2, 2016, 3, 4-Dihydroxyphenylacetic Acid/metabolism, 6-tetrahydropyridine/pharmacology, Alam Gelareh, Animal, Animals, Corpus Striatum/drug effects/*metabolism, Department of Family & Community Medicine, Disease Models, Dopamine/metabolism, Female, Gene Expression Regulation/drug effects/*genetics, Glial Fibrillary Acidic Protein/*metabolism, Homovanillic Acid/metabolism, Inbred Strains, Jones Byron C, Lu Lu, Male, Mice, Miller Diane B, MPTP Poisoning/chemically induced/*pathology, NEOMED College of Medicine, Neurotoxicology, O'Callaghan James P, Serotonin/metabolism, Species Specificity, Tyrosine 3-Monooxygenase/metabolism, Williams Robert W
A quantitative LC-MS/MS method for determination of thiazolidinedione mitoNEET ligand NL-1 in mouse serum suitable for pharmacokinetic studies.
Tags: %CV, %RE, 1-Methyl-4-phenyl-1, 2, 2014, 3, 3-thiazolidine-2, 4-dione, 5-[3, 5-[4-hydroxy-3, 5-di-tert-butyl-4-hydroxyphenyl)methyl]-1, 5-dimethyl-phenyl)methyl]thiazolidine-2, 6-tetrahydropyridine, Anderson David J, Animals, Carroll Richard T, Carry-over, Chromatography, Department of Internal Medicine, Geldenhuys Werner J, High Pressure Liquid/*methods, internal standard, IS, Jogiraju Harini, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, LC-MS/MS, Limit of Detection, Lin Li, LLOQ, lower limit of quantification, Methanol, Mice, mitoNEET, Mouse serum, MPTP, MRM, multiple reaction monitoring, NEOMED College of Medicine, NL-1, NL-2, Pedada Kiran K, percent coefficient of variation, peroxisome proliferator activated receptor-gamma, pharmacokinetic, PK, PPAR-gamma, QC, Quality Control, relative error, relative matrix effect, RME, SD, standard deviation, Tandem Mass Spectrometry/*methods, thiazolidinedione, Thiazolidinedione (TZD), Thiazolidinediones/*blood, TZD, Zhou Xiang
Effects of testosterone upon MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system of C57/B1 mice.
Tags: *MPTP Poisoning, 1-Methyl-4-phenyl-1, 1996, 2, 3, 4-Dihydroxyphenylacetic Acid/metabolism, 6-tetrahydropyridine/*antagonists & inhibitors, Animals, Brain research, Catecholamines/metabolism, Dluzen D E, Dopamine Agents/*toxicity, Dopamine/metabolism/*physiology, Female, Inbred C57BL, Male, Mice, Neostriatum/drug effects/metabolism/*pathology, Nervous System Diseases/chemically induced/*pathology/*prevention & control, Olfactory Bulb/drug effects/metabolism, Orchiectomy, Substantia Nigra/drug effects/metabolism/*pathology, Testosterone/*pharmacology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) disrupts social memory/recognition processes in the male mouse.
Tags: *Social Behavior, 1-Methyl-4-phenyl-1, 1993, 2, 3, 6-tetrahydropyridine/*analogs & derivatives/pharmacology, Animals, Brain Chemistry/drug effects, Brain research, Catecholamines/metabolism, Cognition/*drug effects, Dluzen D E, Dopamine Agents/*pharmacology, Dopamine/metabolism, Habituation, Kreutzberg J D, Levodopa/pharmacology, Male, Memory/*drug effects, Mice, Psychophysiologic/drug effects
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) reduces norepinephrine concentrations in the olfactory bulbs of male mice.
Tags: *Sex Characteristics, 1-Methyl-4-phenyl-1, 1992, 2, 3, 6-tetrahydropyridine/*pharmacology, Animals, Brain research, Dluzen D E, Dopamine/metabolism, Drug Resistance/genetics, Inbred C57BL, Inbred Strains, Male, Mice, Norepinephrine/*metabolism, Olfactory Bulb/*metabolism, Osmolar Concentration