Browse Items · NEOMED Bibliography Database

The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.

BACKGROUND: Neuroinflammation is one of the hallmarks of neurodegenerative diseases, such as Parkinson's disease (PD). Activation of glial cells, including microglia and astrocytes, is a characteristic of the inflammatory response. Glycoprotein…

Findings from a 10-year follow-up of bone mineral density in competitive perimenopausal runners.

OBJECTIVE: To evaluate bone mineral density (BMD) in perimenopausal competitive runners with long-term follow-up. STUDY DESIGN: Fifteen master female runners between 40 and 50 years old who ran at least 20 miles per week were evaluated. BMD was…

Risk factors associated with Clostridium difficile diarrhea in hospitalized adult patients: a case-control study–sucralfate ingestion is not a negative risk factor.

OBJECTIVES: To assess risk factors associated with Clostridium difficile diarrhea in hospitalized adult patients, and to test the hypothesis that sucralfate ingestion is associated with nondetection of C difficile cytotoxin in stool specimens.…

Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes.

Context: Hyperglycemia plays a key role in the pathogenesis of cardiovascular complications of diabetes. Type 2 diabetes mellitus (T2DM) is associated with high-density lipoprotein (HDL) dysfunction and increased degradation of apolipoprotein I…

Tags: 2018, Adult, Aged, Animal Studies, Animals, Apolipoprotein A-I/blood/*metabolism, Apolipoproteins – Blood, Apolipoproteins – Metabolism, Bena James, Biochemical Phenomena, Case Control Studies, Case-Control Studies, Cells, Comparative Studies, Cultured, Department of Pharmaceutical Sciences, Diabetes Mellitus, Diet, Dyslipidemias/complications/diet therapy/*metabolism, Evaluation Research, Female, Funding Source, Glycosylation, Golizeh Makan, HDL – Metabolism, HDL/*metabolism, Human, Humans, Hyperglycemia – Complications, Hyperglycemia – Diet Therapy, Hyperglycemia – Metabolism, Hyperglycemia/complications/diet therapy/*metabolism, Hyperlipidemia – Complications, Hyperlipidemia – Diet Therapy, Hyperlipidemia – Metabolism, Ilchenko Serguei, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Lipoproteins, Male, Mice, Middle Age, Middle Aged, Multicenter Studies, NEOMED College of Pharmacy, Osme Abdullah, Previs Stephen F, Protein Stability, Smith Jonathan D, The Journal of clinical endocrinology and metabolism, Type 2 – Complications, Type 2 – Diet Therapy, Type 2 – Metabolism, Type 2/complications/*diet therapy/metabolism, Validation Studies, Wang Shuhui

Impact of Tranexamic Acid in Total Knee and Total Hip Replacement.

OBJECTIVE: To evaluate the net clinical benefit of tranexamic acid use in patients undergoing total knee or total hip replacement. METHODS: This is a retrospective study of patients undergoing total knee or total hip replacement. The primary outcome…

Tags: 2017, Aged, Antifibrinolytic Agents/adverse effects/therapeutic use, Arthroplasty, Blood Transfusion, Blood Transfusion/statistics & numerical data, Boyle Jaclyn A, Case-Control Studies, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Hemoglobins – Analysis, Hemoglobins/metabolism, Hip, Hip/*methods, Human, Humans, Journal of pharmacy practice, Knee, Knee/*methods, Length of Stay – Evaluation, Length of Stay/statistics & numerical data, Male, NEOMED College of Pharmacy, Outcome Assessment, Replacement, Retrospective Design, Retrospective Studies, Soric Mate M, total hip replacement, total knee replacement, tranexamic acid, Tranexamic Acid – Administration and Dosage, Tranexamic Acid/adverse effects/*therapeutic use, Venous Thromboembolism – Risk Factors, Venous Thromboembolism/epidemiology

MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the

OBJECTIVES: Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of…

Tags: *CYTOKINES, *ETHANOL, *FATTY LIVER, *Inflammation, *LEUKOCYTES, 2017, Adult, Alanine Transaminase/blood, Alcoholic/genetics/*metabolism/pathology, Alcoholism/*blood/complications, Animals, Aspartate Aminotransferases/blood, Bilirubin/blood, Binge Drinking/*blood/complications, Cai Yan, Cao Haixia, Case-Control Studies, Central Nervous System Depressants/administration & dosage, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Down-Regulation, Ethanol/administration & dosage, Female, Feng Dechun, Gao Bin, Gao Yanhang, Gao Yueqiu, Gut, He Yong, Humans, Inbred C57BL, Interleukin-6/genetics/metabolism, Li Man, Liangpunsakul Suthat, Liver Diseases, Male, Mice, MicroRNAs/*blood/*genetics, Middle Aged, NADPH Oxidases/genetics/metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Neutrophils/*metabolism, Ramirez Teresa, Reactive Oxygen Species/metabolism, Ross Ruth A, Up-Regulation, Xu Ming-Jiang, Young Adult, Zhang Ping, Zhou Zhou

Proton pump inhibitors impact on post-endoscopic retrograde cholangiopancreatography pancreatitis.

Factors Predicting Recurrence of Clostridium difficile Infection (CDI) in Hospitalized Patients: Retrospective Study of More Than 2000 Patients.

BACKGROUND: Clostridium difficile infection (CDI) has increased in incidence and severity worldwide, causing direct costs estimated to range from US $3.2 billion to $4.8 billion. The aim of this study was to investigate and identify factors that…

Assessing the Accuracy of Eyelid Measurements Utilizing the Volk Eye Check System and Clinical Measurements.

PURPOSE: The purpose of this study was to validate the accuracy of marginal reflex distance 1 (MRD1) measurements obtained by the Volk Eye Check system, a modified smartphone that measures MRD1 automatically, relative to clinical and digital…

Anti-tobacco socialization in homes of African-American and white parents, and smoking and nonsmoking parents.

PURPOSE: To examine parental perceptions and behaviors with regard to teen smoking, comparing African-American and white parents, and those who did and did not smoke. METHODS: Focus groups consisting of African-American and white parents who smoked…

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

High Body Mass Index in Infancy May Predict Severe Obesity in Early Childhood.

OBJECTIVE: To characterize growth trajectories of children who develop severe obesity by age 6 years and identify clinical thresholds for detection of high-risk children before the onset of obesity. STUDY DESIGN: Two lean (body mass index [BMI] 5th…

Tags: *BMI percentile, *Body Mass Index, *infant growth, *obese, *weight for length, 2017, Age Factors, Bansal Danesh, Bliss Sherri, Body Mass Index, Bolling Christopher, Case Control Studies, Case-Control Studies, Child, Comparative Studies, Crimmins Nancy A, Daniels Stephen R, Evaluation Research, Female, Human, Humans, Incidence, Infant, Klein Jillian, Logistic Models, Logistic Regression, Male, Morbid – Diagnosis, Morbid – Epidemiology, Morbid/*diagnosis/*epidemiology, Multicenter Studies, Newborn, Obesity, Obesity – Diagnosis, Obesity – Epidemiology, Obesity/diagnosis/epidemiology, Predictive Value of Tests, Preschool, Reference Values, Reproducibility of Results, Risk Assessment, Scales, Sex Factors, Smego Allison, Suh Christina, The Journal of pediatrics, Validation Studies, Weight Gain, Woo Jessica G

Phase I/II prospective trial of autologous platelet tissue graft in gynecologic surgery.

STUDY OBJECTIVE: To perform the original phase I/II trial of autologous platelet tissue graft in gynecologic surgery to evaluate toxicity and efficacy on decreasing pain. DESIGN: Prospective nonrandomized trial (Canadian Task Force classification…

Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.

Type 2 diabetes mellitus (T2DM) is associated with oxidative stress and perturbed iron metabolism. Serotransferrin (Trf) and ceruloplasmin (Cp) are two key proteins involved in iron metabolism and anti-oxidant defense. Non-enzymatic glycation and…

Tags: *Ceruloplasmin, *Deamidation, *Heavy water metabolic labeling, *High resolution mass spectrometry, *Iron metabolism, *LC-MS/MS, *Non-enzymatic glycation, *Oxidative Stress, *Protein Processing, *Proteome dynamics, *Serotransferrin, *Type 2 diabetes mellitus, 2017, Adult, Amino Acid Sequence, Bena James, Case-Control Studies, Ceruloplasmin/genetics/*metabolism, Department of Pharmaceutical Sciences, Deuterium/metabolism, Diabetes Mellitus, Diabetic, Diet, Female, Free radical biology & medicine, Gene Expression Regulation, Glycated Hemoglobin A/genetics/metabolism, Glycosylation, Golizeh Makan, Humans, Ilchenko Serguei, Iron/*metabolism, Isotope Labeling, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Male, Middle Aged, NEOMED College of Pharmacy, Osme Abdullah, Oxidation-Reduction, Oxidative Stress, Post-Translational, Proteolysis, Sadygov Rovshan G, Transferrin/genetics/*metabolism, Type 2/diet therapy/genetics/*metabolism/pathology

Cognitive Behavioral Therapy for Psychosis (CBT-p) Delivered in a Community Mental Health Setting: A Case Comparison of Clients Receiving CBT Informed Strategies by Case Managers Prior to Therapy.

This exploratory case comparison examines the influence of case management activities on engagement and progress in psychotherapy for clients with schizophrenia. Six clients were recruited to participate in ten sessions of Cognitive Behavioral…

Tags: *Case Managers, *CBT-p, *Cognitive behavioral techniques for psychosis, *Cognitive behavioral therapy for psychosis, *Community Mental Health Services, *Continuum of care, *Schizophrenia, 2017, Adult, Case Management, Case-Control Studies, Cognitive Behavioral Therapy/*methods, Cognitive Therapy – Methods, Community mental health journal, Community Mental Health Services, Comparative Studies, Continuity of Patient Care, Department of Psychiatry, Evidence-Based, Exploratory Research, Female, Human, Humans, Knepp Kristen A, Male, Middle Aged, Montesano Vicki L, Munetz Mark R, NEOMED College of Medicine, Outcome Assessment, Professional Practice, Program Implementation – Methods, Psychotic Disorders – Therapy, Psychotic Disorders/*therapy, Schizophrenia, Sivec Harry J, Skubby David, Surveys and Questionnaires

The cost of laparoscopic versus open cholecystectomy in a community hospital.

This retrospective study reviewed the hospital and professional costs, charges, and reimbursements for laparoscopic cholecystectomy (lap chole) and open cholecystectomy (open chole) and compared the two procedures. There was no significant difference…

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