Browse Items · NEOMED Bibliography Database

Decreased Tumoral Expression of Colon-Specific Water Channel Aquaporin 8 Is Associated With Reduced Overall Survival in Colon Adenocarcinoma.

Colon cancer survival is dependent on metastatic potential and treatment. Large RNA-sequencing data sets may assist in identifying colon cancer-specific biomarkers to improve patient outcomes.

Tags: 2021, Adenocarcinoma, Adenocarcinoma/*genetics, Aged, aquaporins, Biomarker, colonic neoplasms, Gene Expression, Kaplan-Meier Estimate, Neoplasm Staging, Proto-Oncogene Proteins B-raf/*genetics

Overexpression of beta-catenin and cyclinD1 predicts a poor prognosis in ovarian serous carcinomas.

UNLABELLED: Ovarian serous cancer is the most common subtype of epithelial ovarian cancer, and is the leading cause of death from gynecologic cancer. There is an important need for exploration of diagnostic and prognostic markers for this disease.…

Weighted Lin-Wang tests for crossing hazards.

Lin and Wang have introduced a quadratic version of the logrank test, appropriate for situations in which the underlying survival distributions may cross. In this note, we generalize the Lin-Wang procedure to incorporate weights and investigate the…

Tags: *Survival Analysis, 2014, Algorithms, Animal, Animals, Computational and mathematical methods in medicine, Computer Simulation, Data Interpretation, Disease Models, Humans, Jia Zhenyu, Kaplan-Meier Estimate, Koziol James A, Leukemia/drug therapy, Mice, Models, Reproducibility of Results, Statistical

Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality.

Background: Polymyxins including colistin are an important "last-line" treatment for infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKp). Increasing use of colistin has led to resistance to this cationic antimicrobial peptide.…

Tags: *beta-Lactam Resistance, *carbapenem-resistant Enterobacteriaceae, *Colistin, *Klebsiella pneumoniae, *mortality, *ST258, 2017, Aged, Anti-Bacterial Agents/pharmacology/*therapeutic use, beta-Lactamases/genetics, Bonomo Robert A, Carbapenems/pharmacology/therapeutic use, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Cober Eric, Colistin/pharmacology/*therapeutic use, Comorbidity, Department of Internal Medicine, Doi Yohei, Domitrovic T Nicholas, Evans Scott, Female, Fowler Vance G Jr, Hujer Andrea M, Hujer Kristine M, Humans, Kalayjian Robert C, Kaplan-Meier Estimate, Kaye Keith S, Klebsiella Infections/diagnosis/*drug therapy/*microbiology/mortality, Klebsiella pneumoniae/classification/*drug effects/genetics, Male, Marshall Steve, Microbial Sensitivity Tests, Middle Aged, NEOMED College of Medicine, Perez Federico, Phylogeny, Proportional Hazards Models, Richter Sandra S, Rojas Laura J, Rudin Susan D, Salata Robert A, Salim Madiha, van Duin David, Watkins Richard R

Lack of Association Between Dexamethasone and Long-Term Survival After Non-Small Cell Lung Cancer Surgery.

OBJECTIVE: To evaluate the association between the use of intraoperative dexamethasone with an increase in recurrence-free survival (RFS) and overall survival (OS) after non-small cell lung cancer (NSCLC) surgery. DESIGN: This was a propensity…

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

Osteosarcoma of the spine: experience in 26 patients treated at the Massachusetts General Hospital.

BACKGROUND CONTEXT: Because of the low incidence, treatment recommendations for spinal osteosarcoma are guided by the results of small series and case reports. Many include patients who presented for treatment over the course of three to four…

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