Weighted Lin-Wang tests for crossing hazards.

Weighted Lin-Wang tests for crossing hazards.

Koziol James A; Jia Zhenyu

Computational and mathematical methods in medicine

2014

1905-07

Lin and Wang have introduced a quadratic version of the logrank test, appropriate for situations in which the underlying survival distributions may cross. In this note, we generalize the Lin-Wang procedure to incorporate weights and investigate the performance of Lin and Wang's test and weighted versions in various scenarios. We find that weighting does increase statistical power in certain situations; however, none of the procedures was dominant under every scenario.

*Survival Analysis; Algorithms; Animal; Animals; Computer Simulation; Data Interpretation; Disease Models; Humans; Kaplan-Meier Estimate; Leukemia/drug therapy; Mice; Models; Reproducibility of Results; Statistical

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643457–643457

2014