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Tags: *carbapenem-resistant Enterobacteriaceae

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Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality.

Background: Polymyxins including colistin are an important "last-line" treatment for infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKp). Increasing use of colistin has led to resistance to this cationic antimicrobial peptide.…

Tags: *beta-Lactam Resistance, *carbapenem-resistant Enterobacteriaceae, *Colistin, *Klebsiella pneumoniae, *mortality, *ST258, 2017, Aged, Anti-Bacterial Agents/pharmacology/*therapeutic use, beta-Lactamases/genetics, Bonomo Robert A, Carbapenems/pharmacology/therapeutic use, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Cober Eric, Colistin/pharmacology/*therapeutic use, Comorbidity, Department of Internal Medicine, Doi Yohei, Domitrovic T Nicholas, Evans Scott, Female, Fowler Vance G Jr, Hujer Andrea M, Hujer Kristine M, Humans, Kalayjian Robert C, Kaplan-Meier Estimate, Kaye Keith S, Klebsiella Infections/diagnosis/*drug therapy/*microbiology/mortality, Klebsiella pneumoniae/classification/*drug effects/genetics, Male, Marshall Steve, Microbial Sensitivity Tests, Middle Aged, NEOMED College of Medicine, Perez Federico, Phylogeny, Proportional Hazards Models, Richter Sandra S, Rojas Laura J, Rudin Susan D, Salata Robert A, Salim Madiha, van Duin David, Watkins Richard R

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