Browse Items (21 total)
- Tags: Gene Expression
Genetic Inactivation of ZCCHC6 Suppresses Interleukin‐6 Expression and Reduces the Severity of Experimental Osteoarthritis in Mice.
Tags: 2019, Ahmad Nashrah, ANIMAL experimentation, Ansari Mohammad Y, Arthritis & Rheumatology, Cartilage, CARTILAGE cells, Dactinomycin, Department of Anatomy & Neurobiology, DNA-Binding Proteins, Gene Expression, GENETIC aspects, Green Jonathan, Haqqi Tariq M, In Vivo Studies, Interleukins, June 2019 Update, Khan Nazir M, Mice, MicroRNA, NEOMED College of Medicine, Novak Kimberly, Osteoarthritis, Prevention, Sequence Analysis, Severity of Illness Index, SYNOVITIS, Transcription Factors
Sterol 12alpha-hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP1C Pathway via FGF21 and FGF15.
Tags: *chemokines, *exosomes, *heart failure, *Myocardial infarction, *Stem cells, 2017, Adult, Adult Stem Cells/metabolism/*transplantation, Circulation research, Exosomes/genetics/metabolism, Gene Expression, Heart Diseases/physiopathology/*therapy, Humans, MicroRNAs/genetics/metabolism, Penn Marc S, Regenerative Medicine/methods/trends, Stem Cell Transplantation/*methods
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway.
Tags: 2013, Animal Studies, Apoptosis, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Evidence-based Complementary & Alternative Medicine (eCAM), Experimental Studies, Gene Expression, Hepatocellular, Immunohistochemistry, In Vivo Studies, Mandal Animesh, NEOMED College of Pharmacy, One-Way Analysis of Variance, Pomegranate, Post Hoc Analysis, Protocols, Rats, Samtani Karishma A, STRUCTURAL equation modeling, Thoppil Roslin J, Western
The expression of a catalytically active cholesterol 7 alpha-hydroxylase cytochrome P450 in Escherichia coli.
Tags: 1991, Amino Acid Sequence, Base Sequence, Blotting, Catalysis, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cholesterol/metabolism, Chromatography, Codon, Department of Integrative Medical Sciences, DNA/genetics, Electrophoresis, Escherichia coli/*enzymology, Gene Expression, Li Y C, Liquid, Liver/enzymology, Microsomes, Molecular Sequence Data, NEOMED College of Medicine, Plasmids, Polyacrylamide Gel, Polymerase Chain Reaction, Substrate Specificity, The Journal of biological chemistry, Western
Tags: *Gravitation, *Space Flight, *Weightlessness, 1999, Animals, Bone and Bones/cytology/metabolism/physiology/ultrastructure, Calcification, Chick Embryo, Collagen/genetics/*metabolism/ultrastructure, Crystallization, Gene Expression, Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology, Humans, Landis W J, NASA Discipline Musculoskeletal, Non-NASA Center, Osteoblasts/metabolism, Osteocalcin/genetics/metabolism, Physiologic/*physiology, Tendons/cytology/metabolism/*physiology/ultrastructure, Tomography
Tags: *Aldehyde Reductase/genetics/metabolism, 2011, Adenoviridae, Animal, Animals, Blood Glucose/*metabolism, Chiang John Y L, Cholesterol/analysis, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus/genetics/*metabolism/physiopathology, Disease Models, Fatty Liver/genetics/*metabolism/physiopathology, Ge Xuemei, Gene Expression, Genetic Vectors, Gluconeogenesis/genetics, Homeostasis, Humans, Journal of lipid research, Li Tiangang, Liver/*metabolism/physiopathology, Ma Huiyan, Malondialdehyde/blood, Mice, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, Transfection, Transgenic, Triglycerides/analysis, Yin Liya, Zhang Yanqiao
Tags: 2006, Animals, BMC neuroscience, Carrier Proteins/genetics/*metabolism, Cell Membrane/metabolism, Confocal, Gene Expression, Green Fluorescent Proteins/genetics, Homer Scaffolding Proteins, In Vitro Techniques, Kammermeier Paul J, Metabotropic Glutamate/genetics/*metabolism, Microscopy, Neurons/*metabolism, Rats, Receptor Aggregation/*physiology, Receptors, Superior Cervical Ganglion/cytology, Sympathetic Nervous System/cytology, Transfection, Wistar
Effects of growth hormone transgene expression on vertebrae in a mouse model of osteogenesis imperfecta.
Tags: 2005, Animal, Animals, Beamer Wesley G, Biomechanical Phenomena, Bone Density, Chase Jeff, Department of Family & Community Medicine, Disease Models, Female, Gene Expression, Genetic Therapy/*methods, Havey Robert M, Heterozygote, Human Growth Hormone/*genetics, Humans, Inbred C57BL, King Donna, Male, McEwen Heather A, Mice, NEOMED College of Medicine, Osteogenesis Imperfecta/pathology/physiopathology/*therapy, Patwardhan Avinash G, Sartori Mark, Spine, Spine/pathology/*physiology, Tail, Transgenic, Voronov Leonard
Analysis of osteopontin in mouse growth plate cartilage by application of laser capture microdissection and RT-PCR.
Tags: *Reverse Transcriptase Polymerase Chain Reaction, 2003, Animals, Articular/chemistry/cytology, Cartilage, Chondrocytes/chemistry, Connective tissue research, Gene Expression, Growth Plate/*chemistry/cytology, Hillyer Jennifer, Inbred C57BL, Jacquet Robin, Landis William J, Laser Therapy, Messenger/metabolism, Mice, Microdissection/*methods, Newborn, Non-programmatic, Osteopontin, RNA, Sialoglycoproteins/*analysis/genetics, Tibia, Zhang Jean
Orphan nuclear receptor oestrogen-related receptor gamma (ERRgamma) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.
Tags: 2015, Animals, bile acid, Bile Acids and Salts/metabolism, Cannabinoid, cannabinoid receptors, CB1/agonists/genetics/*metabolism, Cells, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/genetics, cholesterol 7alpha-hydroxylase (CYP7A1), Cultured, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, Drug Inverse Agonism, Estrogen/genetics/*metabolism, Ethanol/pharmacology, Gene Expression, Genetic, Glycerides/pharmacology, GSK5182, HEK293 Cells, Hepatocytes/metabolism, Humans, Inbred C57BL, Jeong Won-Il, Kim Don-Kyu, Kim Seong Heon, Knockout, Lee Chul-Ho, Lee In-Kyu, Lee Ji-Min, Liver/*metabolism, Mice, NEOMED College of Medicine, oestrogen-related receptor gamma (ERRgamma), orphan nuclear receptor, Park Seung Bum, Promoter Regions, Rats, Receptor, Receptors, small heterodimer partner (SHP), Sprague-Dawley, The Biochemical journal, Transcription, Zhang Yaochen
Overexpressing superoxide dismutase 2 induces a supernormal cardiac function by enhancing redox-dependent mitochondrial function and metabolic dilation.
Tags: 2015, Adenosine Triphosphate/biosynthesis, Animals, Arterial Pressure/drug effects, Bioenergetics, Blood Flow Velocity/drug effects, Cardiac function, Cardiac/drug effects/*enzymology, Catalase/pharmacology, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Department of Integrative Medical Sciences, Echocardiography, Female, Gene Expression, Heart/drug effects/*enzymology, Hydrogen Peroxide/*metabolism/pharmacology, Injections, Intravenous, Journal of molecular and cellular cardiology, Kang Patrick T, Luther Daniel J, Male, Meszaros J Gary, Metabolic dilation, Mice, Mitochondria, Myocardium/*enzymology, Myocytes, NEOMED College of Medicine, NG-Nitroarginine Methyl Ester/pharmacology, Ohanyan Vahagn, Oxidation-Reduction, Oxygen Consumption/drug effects, Redox regulation, Signal Transduction, Stroke Volume/drug effects, Superoxide dismutase 2 (SOD2), Superoxide Dismutase/*genetics/metabolism, Transgenic, Transgenic mice, Vasodilation/*drug effects
Evidence of Wnt/beta-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.
Tags: *Alzheimer's disease, *Beta catenin, *Bone mineral density, *neurodegeneration, *Tauopathy, *Wnt proteins, *Wnt Signaling Pathway, 2018, Alzheimer Disease/*genetics/*metabolism, Animal, Animals, Ball Hope C, beta Catenin/metabolism, Bone and Bones/*metabolism, Bone Density, Bone Remodeling/genetics, Brain/*metabolism, Cooper Lisa Noelle, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Female, Gene Expression, Lin Li, Male, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Neurobiology of aging, Novak Kimberly M, Osteogenesis/genetics, Osteoporosis/etiology/genetics, tau Proteins/*metabolism, Tauopathies/genetics/*metabolism, Wnt Proteins/metabolism
Tags: *Butea, 2017, Aged, Ansari Mohammad Y, Autophagy, Autophagy/drug effects/physiology, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Butea monosperma (Lam.), Chondrocytes/drug effects/*metabolism, Department of Anatomy & Neurobiology, Dose-Response Relationship, Drug, Flowers, Gene Expression, Haqqi Tariq M, Humans, Interleukin-1beta/*pharmacology, Interleukin-6/*biosynthesis/genetics, Khan Nazir M, Matrix Metalloproteinase 13/biosynthesis/genetics, Matrix Metalloproteinase 3/biosynthesis/genetics, Matrix Metalloproteinase 9/biosynthesis/genetics, Matrix Metalloproteinases/*biosynthesis/genetics, Middle Aged, mTOR, NEOMED College of Medicine, Nutraceuticals, Osteoarthritis, Osteoarthritis/*metabolism, Plant Extracts/isolation & purification/pharmacology
The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.
Tags: 2019, Acid Anhydride Hydrolases/*metabolism, Animals, Ansari Mohammad Yunus, Baculoviridae/genetics, Bellur Asutosh, Cercopithecus aethiops, Cloning, Conventional mRNA capping, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression, Genetic Vectors/genetics, Messenger/*genetics/*metabolism, Molecular, Morbillivirus, mRNA capping, NEOMED College of Medicine, Peste-des-petits-ruminants virus L protein, Peste-des-petits-ruminants virus/*physiology, Peste-des-Petits-Ruminants/*virology, PPRV, Rajagopalan Deepa, RNA, RNA Caps/*metabolism, RNA triphosphatase, Shaila Melkote Subbarao, Shanmugam Purnima, Singh Piyush Kumar, Vero Cells, Viral Proteins/*metabolism, Virus Genes
Tags: *Protein Processing, 2009, Animals, Archives of virology, Bower John R, Cercopithecus aethiops, Chatterjee Somik, Cismowski Mary J, Cloning, Gene Expression, Herpesvirus 1, Herpesvirus 2, Human/*genetics, Molecular, Post-Translational, Rosenthal Kenneth Steven, Vero Cells, Viral Envelope Proteins/*metabolism, Viral Proteins/genetics/*metabolism, Wang Jason W
Tags: *Pseudogenes, 1993, Amino Acid Sequence, Animals, Base Sequence, Blotting, Cattle/*genetics, Cristiano R J, Cytochromes b5/*genetics, DNA/genetics/isolation & purification, Exons, Gene Expression, Genetic, Genomic Library, Genomics, Giordano S J, Humans, Introns, Messenger/biosynthesis/metabolism, Molecular Sequence Data, Nucleic Acid, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Rabbits, Restriction Mapping, Reticulocytes/metabolism, RNA, RNA Precursors/chemistry/metabolism, Sequence Homology, Southern, Steggles A W, Transcription