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Tags: Estrogen/genetics/*metabolism

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Orphan nuclear receptor oestrogen-related receptor gamma (ERRgamma) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.

Bile acids are primarily synthesized from cholesterol in the liver and have important roles in dietary lipid absorption and cholesterol homoeostasis. Detailed roles of the orphan nuclear receptors regulating cholesterol 7alpha-hydroxylase (CYP7A1),…

Tags: 2015, Animals, bile acid, Bile Acids and Salts/metabolism, Cannabinoid, cannabinoid receptors, CB1/agonists/genetics/*metabolism, Cells, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/*biosynthesis/genetics, cholesterol 7alpha-hydroxylase (CYP7A1), Cultured, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, Drug Inverse Agonism, Estrogen/genetics/*metabolism, Ethanol/pharmacology, Gene Expression, Genetic, Glycerides/pharmacology, GSK5182, HEK293 Cells, Hepatocytes/metabolism, Humans, Inbred C57BL, Jeong Won-Il, Kim Don-Kyu, Kim Seong Heon, Knockout, Lee Chul-Ho, Lee In-Kyu, Lee Ji-Min, Liver/*metabolism, Mice, NEOMED College of Medicine, oestrogen-related receptor gamma (ERRgamma), orphan nuclear receptor, Park Seung Bum, Promoter Regions, Rats, Receptor, Receptors, small heterodimer partner (SHP), Sprague-Dawley, The Biochemical journal, Transcription, Zhang Yaochen

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