Browse Items (14 total)
- Tags: Penn Marc S
The Unraveling of the Matryoshka Doll.
Tags: *chemokines, *exosomes, *heart failure, *Myocardial infarction, *Stem cells, 2017, Adult, Adult Stem Cells/metabolism/*transplantation, Circulation research, Exosomes/genetics/metabolism, Gene Expression, Heart Diseases/physiopathology/*therapy, Humans, MicroRNAs/genetics/metabolism, Penn Marc S, Regenerative Medicine/methods/trends, Stem Cell Transplantation/*methods
Apolipoprotein A1 regulates coenzyme Q10 absorption, mitochondrial function, and infarct size in a mouse model of myocardial infarction.
Tags: *Disease Models, 2014, Animal, Animal Studies, Animals, Antioxidants – Administration and Dosage, Antioxidants – Metabolism, Antioxidants – Pharmacokinetics, Antioxidants – Therapeutic Use, Antioxidants/administration & dosage/*metabolism/pharmacokinetics/therapeutic use, Apolipoprotein A-I/blood/genetics/*metabolism, Apolipoproteins, Apolipoproteins – Blood, Apolipoproteins – Metabolism, Biological, Cardiotonic Agents – Administration and Dosage, Cardiotonic Agents – Metabolism, Cardiotonic Agents – Pharmacokinetics, Cardiotonic Agents – Therapeutic Use, Cardiotonic Agents/administration & dosage/metabolism/pharmacokinetics/therapeutic use, Coenzyme Q, Coenzyme Q – Administration and Dosage, Coenzyme Q – Metabolism, Coenzyme Q – Pharmacokinetics, Coenzyme Q – Therapeutic Use, Dadabayev Alisher R, Dietary Supplements, Electron Transport – Drug Effects, Electron Transport Complex II/chemistry/metabolism, Electron Transport Complex III/chemistry/metabolism, Electron Transport/drug effects, Heart – Drug Effects, Heart/drug effects, Heart/drug effects/enzymology/*metabolism, Hypoalphalipoproteinemias/physiopathology, Inborn Errors – Physiopathology, Injections, Intestinal Absorption, Intraperitoneal, Knockout, Latchoumycandane Calivarathan, Lesnefsky Edward J, Lipid Metabolism, Male, McIntyre Thomas M, Mice, Mitochondria, Mitochondria – Drug Effects, Mitochondria – Metabolism, Models, Myocardial Infarction – Etiology, Myocardial Infarction – Metabolism, Myocardial Infarction – Pathology, Myocardial Infarction – Therapy, Myocardial Infarction/etiology/metabolism/pathology/*therapy, Myocardial Reperfusion Injury – Blood, Myocardial Reperfusion Injury – Metabolism, Myocardial Reperfusion Injury – Pathology, Myocardial Reperfusion Injury – Prevention and Control, Myocardial Reperfusion Injury/blood/metabolism/pathology/prevention & control, Myocardium, Myocardium – Metabolism, Myocardium – Pathology, Myocardium/enzymology/*metabolism/pathology, Penn Marc S, Proteins, Proteins – Metabolism, The Journal of nutrition, Tissue Distribution, Ubiquinone/administration & dosage/*analogs & derivatives/metabolism/pharmacokinetics/therapeutic use, Yin Guotian
Bone marrow SSEA1+ cells support the myocardium in cardiac pressure overload.
Tags: *Bone Marrow Transplantation, 2013, Animals, Bone Marrow Cells/cytology/*metabolism, Cardiac/cytology/metabolism, Cell Tracking, Department of Integrative Medical Sciences, Dong Feng, Finan Amanda, Kiedrowski Matthew, Lewis X Antigen/*metabolism, Male, Mesenchymal Stem Cells/cytology/metabolism, Mice, Myocardium/cytology/*metabolism/pathology, Myocytes, NEOMED College of Medicine, Penn Marc S, PloS one, Sopko Nikolai, Turturice Ben, Ventricular Remodeling
Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction.
Tags: 2012, Agarwal Udit, Animals, Apoptosis/physiology, Cardiac/cytology/physiology, Cell Movement/physiology, Chemokine CXCL12/*metabolism, Circulation, Coronary Circulation/physiology, CXCR4/*genetics/metabolism, Department of Integrative Medical Sciences, Dong Feng, Finan Amanda, Gene Expression/physiology, Green Fluorescent Proteins/genetics, Harvey James, Inbred C57BL, Knockout, Mesenchymal Stem Cell Transplantation/*methods, Mesenchymal Stem Cells/*metabolism, Mice, Myocardial Infarction/genetics/pathology/*therapy, Myocardium/cytology, Myocytes, NEOMED College of Medicine, Paracrine Communication/physiology, Penn Marc S, Receptors, Ventricular Remodeling/physiology, Weber Kristal
An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.
Tags: *Plasmids, 2013, Aged, Aras Rahul, Brain/blood, Chemokine CXCL12/*genetics/metabolism, Circulation research, Clemens Ruth, Cohort Studies, Dose-Response Relationship, Drug, Echocardiography, Exercise Tolerance, Farr Maryjane, Female, Follow-Up Studies, Genetic Therapy/*adverse effects/*methods, Heart Failure/metabolism/pathology/*therapy, Humans, Losordo Douglas W, Male, Mendelsohn Farrell O, Middle Aged, Myocardium/metabolism/pathology, Natriuretic Peptide, Pastore Joseph, Penn Marc S, Peptide Fragments/blood, Positron-Emission Tomography, Quality of Life, Rouy Didier, Schaer Gary L, Sherman Warren, Treatment Outcome
Mesenchymal stem cells and their secretome partially restore nerve and urethral function in a dual muscle and nerve injury stress urinary incontinence model.
Tags: *Mesenchymal Stem Cell Transplantation, 2015, American journal of physiology. Renal physiology, Animals, Balog Brian, Conditioned, Culture Media, Damaser Margot S, Deng Kangli, elastin, external urethral sphincter, Female, Hanzlicek Brett, Hu Zhiquan, Injections, Intraperitoneal, Intravenous, Kiedrowski Matthew J, Lin Dan Li, Mesenchymal Stem Cells/metabolism, paracrine action, Parturition, Penn Marc S, pudendal nerve, Pudendal Nerve/injuries/*physiology, Rats, Sprague-Dawley, Stress/etiology/*prevention & control, Urethra/injuries/*physiology, Urinary Incontinence, Ye Zhangqun, Zhu Hui
Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Tags: 2016, alpha Subunit/metabolism, American journal of physiology. Heart and circulatory physiology, Amino Acids, Animal, Animals, Apoptosis/drug effects, Cardiotonic Agents/*pharmacology, Cell Hypoxia, Cell Line, Chilian William M, CXCR4/deficiency/genetics/*metabolism, Department of Integrative Medical Sciences, Dicarboxylic/*pharmacology, Disease Models, Dong Feng, Enzyme Inhibitors/pharmacology, Forudi Farhad, hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors/metabolism, Inbred C57BL, Kiedrowski Matthew, Knockout, Left/*drug effects, Mayorga Mari, Mice, myocardial infarction, Myocardial Infarction/*drug therapy/genetics/metabolism/pathology/physiopathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Penn Marc S, Rats, Receptors, Recovery of Function, Shamhart Patricia, Signal Transduction/drug effects, stem cells, Stem Cells/drug effects/metabolism, Stroke Volume/drug effects, Time Factors, Up-Regulation, Ventricular Function, Weber Kristal
Effect of Pregnancy and Delivery on Cytokine Expression in a Mouse Model of Pelvic Organ Prolapse.
Tags: 2017, Amino Acid Oxidoreductases/*genetics/metabolism, Animal, Animals, Balog Brian M, Borazjani Ali, Butler Robert S, Chemokine CCL7/genetics/metabolism, Chemokine CXCL12/genetics/metabolism, Couri Bruna M, Damaser Margot S, Delivery, Female, Female pelvic medicine & reconstructive surgery, Humans, Knockout, Kuang Mei, Lenis Andrew T, Mice, Models, Obstetric/*adverse effects/methods, Pelvic Organ Prolapse/*genetics/metabolism/pathology, Penn Marc S, Pregnancy, Reverse Transcriptase Polymerase Chain Reaction, Urethra/metabolism, Urinary Bladder/metabolism, Vagina/metabolism
Are stem cells the teacher or the student?
Coronary collateral growth–back to the future.
Tags: 2012, Chilian William M, Collateral Circulation/*physiology, Coronary Artery Disease/physiopathology/therapy, Coronary Circulation/physiology, Department of Integrative Medical Sciences, Dong Feng, Humans, Journal of molecular and cellular cardiology, Logan Suzanna, Mayorga Maritza, Myocardial Ischemia/physiopathology/therapy, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Penn Marc S, Physiologic/physiology, Pung Yuh Fen, Yin Liya
Role of SDF-1:CXCR4 in Impaired Post-Myocardial Infarction Cardiac Repair in Diabetes.
Tags: 2018, Cardiac, Cell therapy, Chilian William, Department of Integrative Medical Sciences, Diabetes, Dong Feng, Forudi Farhad, Kiedrowski Matthew, Mayorga Maritza E, McCallinhart Patricia, NEOMED College of Medicine, Ockunzzi Jeremiah, Penn Marc S, stem cells, Stem cells translational medicine, Stromal derived factor-1, Weber Kristal
A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome.
Tags: 2017, Calcium/calmodulin-dependent protein kinase kinase-1, Cardiac disease, Cardiac regeneration, Department of Integrative Medical Sciences, Dong Feng, Duan Zhong-Hui, Kiedrowski Matthew, Mayorga Maritza E, Mesenchymal stem cells, NEOMED College of Medicine, Patnaik Shyam, Penn Marc S, Secretome, Stem cells translational medicine