Browse Items (7 total)
- Tags: *Inflammation
Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.
Tags: *Drug Delivery Systems, *Inflammation, *Microglia, *neuroprotection, *polymersomes, *simvastatin, 2017, Animals, Anti-Inflammatory Agents/*pharmacology, Department of Pharmaceutical Sciences, Inbred BALB C, Interleukin-6/antagonists & inhibitors/biosynthesis, Lactates/*administration & dosage, Manickavasagam Dharani, Mice, Microglia/*drug effects, NEOMED College of Pharmacy, Nitric Oxide/antagonists & inhibitors/biosynthesis, Novak Kimberly, Oyewumi Moses O, Polyethylene Glycols/*administration & dosage, Simvastatin/*administration & dosage/pharmacology, The AAPS journal, Tumor Necrosis Factor-alpha/antagonists & inhibitors/biosynthesis
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Tags: *Alzheimers disease, *Immunity, *Inflammation, *Tauopathy, *TREM2, 2017, Allan Kevin, Animal, Animals, Bemiller Shane M, Crish Samuel D, Department of Pharmaceutical Sciences, Disease Models, Formica Shane V, Humans, Immunologic/*deficiency, Inbred C57BL, Kokiko-Cochran Olga N, Lamb Bruce T, Landreth Gary E, Lasagna-Reeves Cristian A, McCray Tyler J, Membrane Glycoproteins/*deficiency, Mice, Microglia/metabolism, Molecular neurodegeneration, NEOMED College of Pharmacy, Protein Kinases/*metabolism, Ransohoff Richard M, Receptors, Signal Transduction/physiology, tau Proteins/*metabolism, Tauopathies/metabolism/*pathology, Transgenic, Wilson Gina, Xu Guixiang
Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice.
Tags: *acetaldehyde dehydrogenase, *alcoholic fatty liver disease, *Inflammation, *small heterodimer partner, 2016, Acetates/blood, Alcoholic/genetics/*metabolism, Aldehyde Dehydrogenase, American journal of physiology. Gastrointestinal and liver physiology, Animals, Cytoplasmic and Nuclear/deficiency/*genetics/metabolism, Department of Integrative Medical Sciences, Ethanol/blood/*metabolism/toxicity, Inbred C57BL, Lee Mikang, Lee Yoon-Kwang, Lipid Peroxidation, Liver Diseases, Liver/drug effects/metabolism, Male, Mice, Mifflin Ryan, Mitochondrial/genetics/metabolism, NEOMED College of Medicine, Park Jung Eun, PPAR gamma/genetics/metabolism, Receptors
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the
Tags: *CYTOKINES, *ETHANOL, *FATTY LIVER, *Inflammation, *LEUKOCYTES, 2017, Adult, Alanine Transaminase/blood, Alcoholic/genetics/*metabolism/pathology, Alcoholism/*blood/complications, Animals, Aspartate Aminotransferases/blood, Bilirubin/blood, Binge Drinking/*blood/complications, Cai Yan, Cao Haixia, Case-Control Studies, Central Nervous System Depressants/administration & dosage, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Down-Regulation, Ethanol/administration & dosage, Female, Feng Dechun, Gao Bin, Gao Yanhang, Gao Yueqiu, Gut, He Yong, Humans, Inbred C57BL, Interleukin-6/genetics/metabolism, Li Man, Liangpunsakul Suthat, Liver Diseases, Male, Mice, MicroRNAs/*blood/*genetics, Middle Aged, NADPH Oxidases/genetics/metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Neutrophils/*metabolism, Ramirez Teresa, Reactive Oxygen Species/metabolism, Ross Ruth A, Up-Regulation, Xu Ming-Jiang, Young Adult, Zhang Ping, Zhou Zhou
Hematologic counts as predictors of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
Tags: *Blood Cell Count, *Inflammation, *Intracranial vasospasm, *Subarachnoid hemorrhage, *Transcranial Doppler sonography, 2017, Anemia/blood/diagnosis, Brain Ischemia/blood/complications/*diagnosis/epidemiology, Cerebrovascular Circulation/physiology, Critical Care, Da Silva Ivan Rocha Ferreira, Databases, de Freitas Gabriel Rodriguez, Doppler, Factual, Female, Gomes Joao Antonio, Humans, Journal of critical care, Leukocytosis/blood/diagnosis, Logistic Models, Male, Middle Aged, Models, Odds Ratio, Ohio/epidemiology, Provencio Jose Javier, Sensitivity and Specificity, Subarachnoid Hemorrhage/*complications/diagnostic imaging, Theoretical, Transcranial, Ultrasonography, Wachsman Ari
The Role of MicroRNAs and Their Targets in Osteoarthritis.
Tags: *Cartilage, *Inflammation, *MicroRNA, *OSTEOARTHRITIS, *Targets, 2016, Articular/*metabolism, Cartilage, Current rheumatology reports, Department of Anatomy & Neurobiology, Haqqi Tariq M, Inflammation/genetics/*metabolism, Intracellular Signaling Peptides and Proteins, MicroRNAs/genetics/*metabolism, NEOMED College of Medicine, Osteoarthritis/genetics/*metabolism, Sondag Gregory R