Browse Items (15 total)
- Tags: Down-Regulation
Tags: 2005, American Journal of Physiology-Gastrointestinal and Liver Physiology, Ananthanarayanan M, bile-acid transporter, Chen F, Chiang J Y L, Cloning, Down-Regulation, Forman B M, Gastroenterology & Hepatology, identification, ileal, Journal Article or Conference Abstract Publication, Li H, messenger-rna, negative feedback-regulation, Nuclear Receptor, Pan L X, Physiology, Rats, real-time, Salen G, Shang Q, Shneider B L, Tint G S, Xu G R
Delphinidin Inhibits Il-1 Beta-induced Activation Of Nf-kappa B By Modulating The Phosphorylation Of Irak-1(ser376) In Human Articular Chondrocytes
Tags: 2013, Chen D X, Chondrocytes, COX-2, delphinidin, Down-Regulation, factor-alpha, gene-expression, Haqqi T M, Haseeb A, human osteoarthritis chondrocytes, IL-1 beta, in-vitro, interleukin-1, Journal Article or Conference Abstract Publication, Kinase, nf-kappa-b, Osteoarthritis, Oxidative Stress, PGE(2), rheumatoid-arthritis, Rheumatology, tumor-necrosis-factor
Regulation of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7A): Prevalence of negative over positive transcriptional control
Tags: 1996, BILE acids, Biochemical and biophysical research communications, Biochemistry & Molecular Biology, Biophysics, Chiang J Y L, Crestani M, cultures, DeFabiani E, Down-Regulation, Galli G, HMG-CoA reductase, hormonal-regulation, hypophysectomized rats, Journal Article or Conference Abstract Publication, Marrapodi M, messenger-rna levels, Pinelli A, primary, protein-kinase-c, rat hepatocytes, thyroid-hormone
Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4 alpha (HNF4 alpha)
Tags: 2003, alpha-fetoprotein transcription factor, Bile acid synthesis, cerebrotendinous xanthomatosis, Chen W L, Chiang J Y L, cholesterol 7-alpha-hydroxylase, cholic-acid, Down-Regulation, factor 4-alpha, Farnesoid X receptor, gene, Genetics & Heredity, hepatocytes, heterodimer partner, Journal Article or Conference Abstract Publication, Liver, negative feedback-regulation, Nuclear Receptor, rat, Small, transcriptional regulation, x-receptor
An overlapping binding site in the CYP7A1 promoter allows activation of FXR to override the stimulation by LXR alpha
Tags: 2007, 7-alpha-hydroxylase gene, activity, American Journal of Physiology-Gastrointestinal and Liver Physiology, bile-acid biosynthesis, Chiang J Y L, Cholesterol, cholesterol 7 alpha-hydroxylase, dietary-cholesterol, Down-Regulation, farnesoid X, fetoprotein transcription factor, Gastroenterology & Hepatology, heterodimer partner, Journal Article, liver X receptor, LXR binding site, messenger-rna, Metabolism, orphan nuclear receptor, Pan L X, Physiology, rat, Receptor, regulation, Salen G, Saumoy M, Shang Q, short, Tint G S, transcriptional, x-receptor, Xu G R
Lung edema clearance: 20 years of progress selected contribution: Long-term effects of beta(2)-adrenergic receptor stimulation on alveolar fluid clearance in mice
Tags: 2002, acute lung injury, alveolar, beta-adrenergic-receptor, Desensitization, Down-Regulation, Epithelium, Fang X, Folkesson H G, hydrostatic pulmonary-edema, in-vivo, Journal Article, Journal of Applied Physiology, Koch P, liquid clearance, lung fluid balance, Matthay M A, McGraw D W, messenger-rna, Physiology, pulmonary edema, rat lung, resolution, Sartori C, Snider M E, sodium transport, Sport Sciences
Tags: 2004, Bhathena A, bile acid, Cheng P Y, Chiang J Y L, cholesterol 7 alpha-hydroxylase, cyp2c11 gene, cyp7a1 transcription, Down-Regulation, Drug Metabolism and Disposition, Jahan A, Journal Article, Lee C, messenger-rna, Miller K K M, Morgan E T, Nuclear Receptor, Pharmacology & Pharmacy, polycyclic aromatic-hydrocarbons, Pregnane X Receptor, Prough R A, rat-liver, Riddick D S, Ripp S L, Timsit Y E
Characterization of vascular endothelial growth factor (VEGF) in the uterine cervix over pregnancy: effects of denervation and implications for cervical ripening.
Tags: 2004, Animal/*metabolism, Animals, Cervical Ripening/*metabolism, Cervix Uteri/blood supply/innervation/*metabolism, Denervation, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme-Linked Immunosorbent Assay, Female, Hattori Y, Immunohistochemistry, Jesmin S, Microcirculation, Mowa C N, NEOMED College of Medicine, Nitric Oxide Synthase Type III, Nitric Oxide Synthase/biosynthesis, Papka R, Phosphorylation, Pregnancy, Protein Isoforms/biosynthesis/metabolism, Protein-Serine-Threonine Kinases/biosynthesis, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/biosynthesis, Rats, Reverse Transcriptase Polymerase Chain Reaction, Sakuma I, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Togashi H, Usip S, Vascular Endothelial Growth Factor A/biosynthesis/*metabolism, Vascular Endothelial Growth Factor Receptor-2/biosynthesis, Wistar, Yoshioka M
Advanced osteoarthritis in humans is associated with altered collagen VI expression and upregulation of ER-stress markers Grp78 and bag-1.
Tags: 2009, Adult, Antigens/biosynthesis, Articular/metabolism, Baraga Anthony, Biomarkers/metabolism, Bone Neoplasms/metabolism, Cartilage, Chondrosarcoma/metabolism, Collagen Type VI/*biosynthesis, Department of Anatomy & Neurobiology, DNA-Binding Proteins/*biosynthesis, Doane Kathleen J, Down-Regulation, Endoplasmic Reticulum/*metabolism, Gradisar Ian, Heat-Shock Proteins/*biosynthesis, Horton Walter E Jr, Humans, Knee/*metabolism/physiopathology, McBurney Denise L, Middle Aged, NEOMED College of Medicine, Nugent Ashleigh E, Osteoarthritis, Osteosarcoma/metabolism, Proteoglycans/biosynthesis, Speicher Danielle M, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Transcription Factors/*biosynthesis, Up-Regulation
Tags: *CYTOKINES, *ETHANOL, *FATTY LIVER, *Inflammation, *LEUKOCYTES, 2017, Adult, Alanine Transaminase/blood, Alcoholic/genetics/*metabolism/pathology, Alcoholism/*blood/complications, Animals, Aspartate Aminotransferases/blood, Bilirubin/blood, Binge Drinking/*blood/complications, Cai Yan, Cao Haixia, Case-Control Studies, Central Nervous System Depressants/administration & dosage, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Down-Regulation, Ethanol/administration & dosage, Female, Feng Dechun, Gao Bin, Gao Yanhang, Gao Yueqiu, Gut, He Yong, Humans, Inbred C57BL, Interleukin-6/genetics/metabolism, Li Man, Liangpunsakul Suthat, Liver Diseases, Male, Mice, MicroRNAs/*blood/*genetics, Middle Aged, NADPH Oxidases/genetics/metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Neutrophils/*metabolism, Ramirez Teresa, Reactive Oxygen Species/metabolism, Ross Ruth A, Up-Regulation, Xu Ming-Jiang, Young Adult, Zhang Ping, Zhou Zhou
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko
Tags: *Apoptosis, 2015, 3' Untranslated Regions, Aged, Chondrocytes/*metabolism/pathology, Department of Anatomy & Neurobiology, Down-Regulation, Experimental & molecular medicine, Female, Gene Expression Regulation, Haqqi Tariq M, Humans, Interleukin-6/*genetics, Makki Mohammad Shahidul, Male, Messenger/genetics, MicroRNAs/*genetics, Middle Aged, NEOMED College of Medicine, Osteoarthritis/*genetics/pathology, Ribonucleases/*genetics, RNA, Transcription Factors/*genetics, Up-Regulation
Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis.
Tags: 2003, Afferent/metabolism, Amann R, Animals, Cervix Uteri/cytology/*metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Estradiol/*analogs & derivatives/pharmacology, Estrogen/antagonists & inhibitors, Estrogens/*pharmacology, Female, Fulvestrant, Ganglia, Immunohistochemistry, In Situ Hybridization, Messenger/genetics/metabolism, Mowa C N, NEOMED College of Medicine, Neurons, Papka R, Peptides, Postpartum Period, Pregnancy/*metabolism, Radioimmunoassay, Rats, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Spinal Cord/cytology/*metabolism, Spinal/cytology/*metabolism, Sprague-Dawley, Storey-Workley M, Substance P/*biosynthesis/genetics/metabolism, Up-Regulation, Usip S
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Anthocyanins/*therapeutic use, Anticarcinogenic Agents/therapeutic use, Apoptosis/drug effects, bcl-2-Associated X Protein/metabolism, Bishayee Anupam, Cell Proliferation/drug effects, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Down-Regulation, Experimental/metabolism/pathology, Folkesson Hans G, Haznagy-Radnai Erzsebet, Hohmann Judit, Liver Neoplasms, Liver Neoplasms/chemically induced/*prevention & control, Liver/pathology, Male, Mbimba Thomas, NEOMED College of Pharmacy, Phenobarbital, Plant Extracts/*therapeutic use, Proliferating Cell Nuclear Antigen/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Rats, Ribes/chemistry, Sipos Peter, Sprague-Dawley, The Journal of nutritional biochemistry, Thoppil Roslin J, Up-Regulation
Coordinate down-regulation of cartilage matrix gene expression in Bcl-2 deficient chondrocytes is associated with decreased SOX9 expression and decreased mRNA stability.
Tags: 2003, Aggrecans, Animals, C-Type, Cell Line, Chondrocytes/*physiology, Collagen Type II/genetics/metabolism, Dactinomycin, Down-Regulation, Extracellular Matrix Proteins/analysis/genetics/*metabolism, Gene Expression Regulation, Glycoproteins/analysis/genetics/*metabolism, High Mobility Group Proteins/genetics/*metabolism, Horton Walter E Jr, Journal of cellular biochemistry, Kinkel Mary D, Lectins, Matrilin Proteins, Messenger/analysis/biosynthesis, Polymerase Chain Reaction/methods, Proteoglycans/genetics/metabolism, Proto-Oncogene Proteins c-bcl-2/deficiency/genetics/*physiology, Rats, RNA, RNA Stability, Signal Transduction, SOX9 Transcription Factor, Transcription Factors/genetics/*metabolism, Transfection