Browse Items (47 total)
- Tags: Gene Expression Regulation
Tags: *Disease Susceptibility, *Signal Transduction, 2018, Animals, Carrier Proteins/chemistry/genetics/*metabolism, Gene Expression Regulation, Humans, Hussein Nazar J, International journal of molecular medicine, Mbimba Thomas, Najeed Ayesha, Protein Binding, Protein Interaction Domains and Motifs, Protein Transport, Safadi Fayez F, Structure-Activity Relationship
On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Tags: *DNA-Binding Proteins, 2002, alpha-Fetoproteins/genetics/*physiology, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Biochimica et biophysica acta, Cattle, Chiang John Y L, Cytochrome P-450 Enzyme System/*genetics, Department of Integrative Medical Sciences, DNA, Eggertsen Gosta, Enzymologic/*drug effects/physiology, Gene Expression Regulation, Genetic, Genetic/*drug effects, Hepatocyte Nuclear Factor 4, Messenger/genetics, NEOMED College of Medicine, Phosphoproteins/genetics/*physiology, Promoter Regions, Rats, RNA, Sprague-Dawley, Steroid 12-alpha-Hydroxylase, Steroid Hydroxylases/*genetics, Transcription, Transcription Factors/genetics/*physiology, Yang Yizeng, Zhang Ming
Tags: 2001, Base Sequence, Binding, Binding Sites/genetics, Cell Line, Chiang J Y, Competitive, CpG Islands/genetics, Cultured, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 7, Department of Integrative Medical Sciences, DNA/genetics, Enzymologic, gene, Gene Expression Regulation, Genetic, Humans, Luciferases/genetics/metabolism, Molecular Sequence Data, Mutagenesis, NEOMED College of Medicine, Nucleic Acid/genetics, Protein Binding, Recombinant Fusion Proteins/genetics/metabolism, Regulatory Sequences, Sequence Deletion, Site-Directed, Sp1 Transcription Factor/metabolism/*physiology, Steroid Hydroxylases/*genetics/metabolism, Transcription, Transfection, Tumor Cells, Wu Z
Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells.
Tags: *Promoter Regions, *Transcription, *Transcription Factors, 1996, Base Sequence, Binding Sites, Cell Line, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics, Consensus Sequence, Crestani M, Department of Integrative Medical Sciences, DNA-Binding Proteins/genetics/metabolism, Enzyme Repression, Enzymologic/*drug effects, Galli G, Gene Expression Regulation, Genes, Genetic, Glucocorticoid/genetics/metabolism, Glucocorticoids/pharmacology, Hepatocyte Nuclear Factor 3-alpha, Humans, Insulin/pharmacology, Journal of lipid research, Marrapodi M, Molecular Sequence Data, NEOMED College of Medicine, Nuclear Proteins/genetics/metabolism, Phorbol Esters/pharmacology, Receptors, Recombinant Fusion Proteins/biosynthesis, Reporter, Stroup D, Thyroid Hormones/pharmacology, Transfection, Wang D P
Peroxisome proliferator-activated receptor alpha (PPARalpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription.
Tags: *DNA-Binding Proteins, *Regulatory Sequences, 2000, Animals, Anticholesteremic Agents/pharmacology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Binding Sites, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics, Clofibric Acid/pharmacology, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Enzymologic, Gene Expression Regulation, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Marrapodi M, Models, NEOMED College of Medicine, Nucleic Acid, Peroxisome Proliferators/pharmacology, Phosphoproteins/metabolism, Promoter Regions, Protein Binding, Pyrimidines/pharmacology, Rats, Receptors, Reporter, Response Elements, Retinoic Acid/metabolism, Retinoid X Receptors, Species Specificity, Transcription, Transcription Factors/*agonists/metabolism, Transcriptional Activation
Rat alpha(2)-macroglobulin inhibits NGF-promoted neurite outgrowth, TrK phosphorylation, and gene expression of pheochromocytoma PC12 cells.
Tags: 1999, Adrenal Gland Neoplasms/metabolism, alpha-Macroglobulins/*pharmacology, Animals, Gene Expression Regulation, Journal of neuroscience research, Koo P H, Lee P G, Neoplastic/*drug effects, Nerve Growth Factors/*antagonists & inhibitors, Neurites/*drug effects, PC12 Cells, Pheochromocytoma/metabolism, Phosphorylation, Proto-Oncogene Proteins c-jun/genetics, Rats, Receptor, Sprague-Dawley, trkA/*metabolism
Tags: 1990, Aflatoxin B1, Aflatoxins/immunology/*metabolism, Animals, Antibodies/immunology, Chiang J Y, Cricetinae, Cytochrome P-450 Enzyme System/biosynthesis/isolation & purification/*metabolism, Department of Integrative Medical Sciences, Enzyme Induction/drug effects, Enzymologic, Gene Expression Regulation, Inbred Strains, Journal of biochemical toxicology, Lai T S, Liver/drug effects/*enzymology, Liver/enzymology, Mesocricetus, Methylcholanthrene/*pharmacology, Microsomes, Mutagenicity Tests, NEOMED College of Medicine, Rats, Salmonella typhimurium/enzymology/genetics, Subcellular Fractions/drug effects/enzymology
Tags: *Promoter Regions, *Transcription, 1995, Animals, Base Sequence, Cell Count, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Crestani M, Cultured, Cyclic AMP/pharmacology, Department of Integrative Medical Sciences, Enzymologic/*physiology, Gene Expression Regulation, Genetic, Hormones/*pharmacology, Journal of lipid research, Luciferases/genetics, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Phorbol Esters/pharmacology, Rats, Second Messenger Systems/physiology, Stroup D, Transfection, Tumor Cells
Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter.
Tags: *Promoter Regions, 1994, Animals, Antigens, Base Sequence, Bile Acids and Salts/*metabolism, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Cloning, Deoxyribonuclease I, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Enzymologic, Gene Expression Regulation, Genetic, Humans, Luciferases/genetics, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Nuclear Proteins/metabolism, Oligodeoxyribonucleotides, Polyomavirus Transforming/genetics, Rats, Recombinant Fusion Proteins/genetics/metabolism, Sprague-Dawley, Stroup D, The Journal of biological chemistry, Thyroid Hormones/genetics
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-kappaB and Nrf2 Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/toxicity, 2017, 9, Animal Studies, Animals, Anti-Inflammatory Agents/*pharmacology, anti-inflammatory effects, Anticarcinogenic Agents/pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms, breast tumor, Cell Transformation, Chemoprevention, COX-2, Cyclooxygenase 2/genetics/metabolism, DMBA, Dose-Response Relationship, Drug, Experimental/*prevention & control, Female, Gene Expression Regulation, HSP90, HSP90 Heat-Shock Proteins/genetics/metabolism, I-kappa B Kinase/genetics/metabolism, Inflammation Mediators, Mammary Neoplasms, Mandal Animesh, Neoplasms – Prevention and Control, Neoplastic, Neoplastic/drug effects, NF-E2-Related Factor 2/genetics/*metabolism, NF-kappa B/genetics/*metabolism, NF-kappaB, Nrf2, Nutrients, Physical Education and Training, Plant Preparations/*pharmacology, Pomegranate, Punica granatum, Punicaceae/*chemistry, Rats, Signal Transduction
Tags: 1998, Animals, Bile Acids and Salts/*biosynthesis, Chiang J Y, Cholestanetriol 26-Monooxygenase, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cholesterol/metabolism, Cytochrome P-450 Enzyme System/metabolism, Cytochrome P450 Family 7, Department of Integrative Medical Sciences, Frontiers in bioscience : a journal and virtual library, Gene Expression Regulation, Humans, Liver/metabolism, NEOMED College of Medicine, Steroid 12-alpha-Hydroxylase/metabolism, Steroid Hydroxylases/metabolism
Six stroma-based RNA markers diagnostic for prostate cancer in European-Americans validated at the RNA and protein levels in patients in China.
Tags: 2015, 80 and over, Adult, Aged, Biomarkers, China, Deng Mingsen, Diagnosis, European Continental Ancestry Group/genetics, Gao Hengjun, Gene Expression Profiling, Gene Expression Regulation, Humans, Jia Zhenyu, Jiang Jun, Male, McClelland Michael, Men Bozhao, Mercola Dan, microenvironment, Middle Aged, Neoplastic, Oncotarget, Pan Cong, Prostate cancer, Prostate/pathology, Prostatic Neoplasms/*diagnosis/*genetics, Race, stroma, Tumor Microenvironment, Tumor/*genetics, Young Adult, Zhong Wei-D, Zhu Jian-Guo
Tags: 2009, Animals, Bile Acids and Salts/*metabolism, Chiang John Y L, Department of Integrative Medical Sciences, Expert opinion on drug metabolism & toxicology, Gene Expression Regulation, Genetic Predisposition to Disease, Hepatocyte Nuclear Factor 4/genetics/*metabolism, Humans, Lipid Metabolism, Liver/metabolism, Mutation, NEOMED College of Medicine, Pharmaceutical Preparations/*metabolism, Signal Transduction/physiology
MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor.
Tags: 2015, Carson Mary, Carson William E 3rd, Cell Line, Cell Movement/genetics, Cell Proliferation/genetics, Chan Anthony N, Dao Thao-Vi, Fairchild Ene T, Ganju Akaansha, Gene Expression Regulation, Grignol Valerie P, Humans, Jaime-Ramirez Alena Cristina, Karpa Volodymyr I, Latchana Nicholas, Levine Kala M, Martin del Campo Sara E, Melanoma/*genetics/metabolism/pathology, MicroRNAs/*genetics/metabolism, Neoplasm Invasiveness/*genetics/pathology, Neoplastic, PloS one, RNA, Skin Neoplasms/*genetics/metabolism/pathology, Small Interfering, Tissue Inhibitor of Metalloproteinase-3/*genetics/metabolism, Tumor
Tags: *Postprandial Period, 2014, Acetylation/drug effects, Animals, ATP Citrate (pro-S)-Lyase/metabolism, Blood Glucose/*metabolism, Carboxylic Ester Hydrolases/*metabolism, Cheng Gang, Chromatin/metabolism, Department of Integrative Medical Sciences, Enzymologic/drug effects, Gene Expression Regulation, Glucose/*pharmacology, Histones/metabolism, Homeostasis, Inbred C57BL, Li Yuanyuan, Liver/*enzymology, Male, Mice, NEOMED College of Medicine, Nutritional Status, PloS one, Xu Jiesi, Xu Yang, Yin Liya, Zalzala Munaf, Zhang Yanqiao
Tags: *Gene Expression Profiling, *Transcriptome, 2014, 80 and over, Adaptive Immunity/genetics, Adult, Age Factors, Aged, Agrawal Anshu, Antigen-Presenting Cells/immunology/metabolism, Cao Jia-ning, Cluster Analysis, Dendritic Cells/immunology/*metabolism, Female, G1 Phase, Gene Expression Regulation, Gupta Sudhir, Healthy Volunteers, Humans, Immunity, Innate/genetics, Jia Zhenyu, Male, PloS one, Sharman Edward, Young Adult
A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes.
Tags: 2010, 3' Untranslated Regions/genetics, Base Sequence, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Department of Integrative Medical Sciences, Enzymologic/drug effects/*genetics, Fibroblast Growth Factors/pharmacology, Gene Expression Regulation, Genetic/drug effects/genetics, Hep G2 Cells, Hepatocytes/drug effects/enzymology/*metabolism, Humans, Isoxazoles/pharmacology, Journal of lipid research, Li Tiangang, MicroRNAs/*genetics/*metabolism, NEOMED College of Medicine, Oligonucleotide Array Sequence Analysis, Owsley Erika, Post-Transcriptional/drug effects/genetics, RNA Processing, Song Kwang-Hoon, Transcription
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth.
Tags: *Collateral Circulation, *Coronary Circulation, 2012, Animal, Animals, Bailey Erin, Biomarkers/metabolism, Cell Differentiation, Cell Lineage, Cells, Chilian William M, Circulation research, Coronary Occlusion/genetics/metabolism/pathology/physiopathology/*surgery, Coronary Vessels/metabolism/pathology/*physiopathology, Cultured, Delucia Angelo, Department of Integrative Medical Sciences, Developmental, Disease Models, Endothelial Cells/metabolism/pathology/*transplantation, Enrick Molly, Epigenesis, Gene Expression Profiling, Gene Expression Regulation, Genetic, Guarini Giacinta, Induced Pluripotent Stem Cells/metabolism/*transplantation, Kolz Christopher L, Mice, Muscle, Myocytes, NEOMED College of Medicine, Neovascularization, Ohanyan Vahagn, Physiologic, Pung Yuh Fen, Rats, Regenerative Medicine/methods, Regional Blood Flow, Reverse Transcriptase Polymerase Chain Reaction, SCID, Smooth, Smooth Muscle/metabolism/pathology/*transplantation, Sprague-Dawley, Stevanov Kelly, Teratoma/metabolism/pathology, Time Factors, Transcription Factors/genetics/metabolism, Transduction, Vascular/metabolism/pathology/*physiopathology, Yin Liya
Tags: 2011, Animals, Bone Regeneration/genetics/*physiology, Cartilage/*physiology, Cattle, Cells, tissues, organs, Collagen Type I/genetics/metabolism, Collagen Type II/genetics/metabolism, Core Binding Factor Alpha 1 Subunit/genetics/metabolism, Gene Expression Regulation, Integrin-Binding Sialoprotein/genetics/metabolism, Isogai Noritaka, Jacquet Robin, Landis William J, Lowder Elizabeth, Matsushima Seika, Mice, Nude, Periosteum/anatomy & histology/diagnostic imaging/*physiology, Prosthesis Implantation, Radiography, Tissue Engineering, Tissue Scaffolds, Tokui Taku
Tags: 2014, Algorithms, Area Under Curve, Computational and mathematical methods in medicine, Computational Biology/*methods, Data Mining/*methods, False Positive Reactions, Fang Ming, Gene Expression Profiling/methods, Gene Expression Regulation, Gene Regulatory Networks, Hu Xingchi, Humans, Jia Zhenyu, Li Lun, MicroRNAs/*genetics/*metabolism, Neoplasms/*genetics/metabolism, Neoplastic, Probability, Reproducibility of Results, Yang Zhaowan, Zhang Libin, Zhou Yanhong
Estrogen-related receptor gamma controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.
Tags: 2013, Alcohol-Induced Injury, Alcoholic Liver Disease, Alcoholic/genetics/*metabolism/prevention & control, Animals, Cannabinoid, CB1/*physiology, Chiang John Y L, Choi Hueng-Sik, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP2E1/genetics/*metabolism, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology/therapeutic use, Enzymologic/drug effects/physiology, Estrogen/deficiency/genetics/*physiology, Ethanol/pharmacology, Gene Expression Profiling/methods, Gene Expression Regulation, Gene Regulation, Genetic/physiology, Gut, Inbred C57BL, Jang Hyun-Hee, Jeong Won-Il, Kim Don-Kyu, Kim Jung Ran, Kim Yong-Hoon, Knockout, Koh Minseob, Koo Seung-Hoi, Lee Chul-Ho, Liver, Liver Diseases, Liver Metabolism, Liver/metabolism, Male, Mice, NEOMED College of Medicine, Oxidation-Reduction, Oxidative Stress/physiology, Park Jinyoung, Park Seung Bum, Park Tae-Sik, Receptor, Receptors, Signal Transduction/drug effects/physiology, Tamoxifen/analogs & derivatives/pharmacology/therapeutic use, Transcription, Yun Chul-Ho
Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner.
Tags: 2015, Animals, Cytochrome P-450 CYP2D6/*biosynthesis, Cytochrome P-450 Enzyme Inhibitors/*pharmacology, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Drug metabolism and disposition: the biological fate of chemicals, Enzymologic/drug effects, Gene Expression Regulation, Genetic/drug effects/genetics, HEK293 Cells, Hepatocytes/drug effects/enzymology/metabolism, Humans, Isoxazoles/*pharmacology, Jeong Hyunyoung, Knockout, Lee Yoon-Kwang, Mice, NEOMED College of Medicine, Pan Xian, Receptors, Transcription, Transgenic
Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
Tags: *Punicaceae/chemistry, 10-Dimethyl-1, 2-benzanthracene, 2016, 9, Animal Studies, Animals, Anticarcinogenic Agents/*therapeutic use, Apoptosis, Apoptosis/*drug effects, Bhatia Deepak, Bhattacharyya Piyali, Bishayee Anupam, Breast Neoplasms – Mortality, Breast Neoplasms – Prevention and Control, Breast Neoplasms – Risk Factors, Cell Physiology, Cell Proliferation/*drug effects, Diet – Evaluation, Experimental/pathology/*prevention & control, Female, Funding Source, Gene Expression Regulation, Genes, Human, Immunohistochemistry, Mammary Neoplasms, Mandal Animesh, Mutation, National Institutes of Health (U.S.), Neoplasms – Prevention and Control, Nutrition and cancer, Phytotherapy, Pomegranate, Proto-Oncogene Proteins c-bcl-2/analysis, Rats, Sprague-Dawley, Tamoxifen, United States
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis.
Tags: 2005, Animals, Annexin A5/metabolism, Anti-Bacterial Agents/metabolism, Apoptosis/*physiology, Biomarkers, Carlson Sara G, Caspase 12, Caspases/metabolism, CCAAT-Enhancer-Binding Proteins/metabolism, Cell Differentiation/*physiology, Cells, Chondrocytes/cytology/*physiology, Collagen Type II/metabolism, Cultured, Department of Anatomy & Neurobiology, DNA Fragmentation, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/metabolism, Gene Expression Regulation, Glucose/metabolism, Horton Walter E Jr, McBurney Denise, NEOMED College of Medicine, Proliferating Cell Nuclear Antigen/metabolism, Rats, Signal Transduction/*physiology, Thapsigargin/metabolism, The Journal of biological chemistry, Transcription Factor CHOP, Transcription Factors/metabolism, Tunicamycin/metabolism, Yang Ling
Tags: *Body Patterning, 2006, Animals, Bajpai S, Cell Polarity, Cohn M J, Department of Anatomy & Neurobiology, Developmental, Dolphins/*embryology/genetics/metabolism, Gene Expression Regulation, Heyning J, Hindlimb/cytology/*embryology/metabolism, Horton W E Jr, Limb Buds/cytology/embryology/metabolism, NEOMED College of Medicine, Phylogeny, Proceedings of the National Academy of Sciences of the United States of America, Stevens L S, Thewissen J G M
Tags: 2016, Affo Silvia, Alcoholic/*immunology, Altamirano Jose, Animals, Arroyo Vicente, Bataller Ramon, Caballeria Juan, Cell Proliferation, Cells, Chen Jiegen, Collagen/genetics/metabolism, Common/*pathology, Crews Fulton, Cultured, Department of Pharmaceutical Sciences, Dumitru Raluca, Female, Gene Expression Profiling, Gene Expression Regulation, Gines Pere, Hepatic Duct, Hepatitis, Hepatocytes/*metabolism/pathology, Humans, Inbred BALB C, Keratins, Knockout, Lipopolysaccharides/metabolism, Lozano Juan Jose, Male, Matsushita Hiroshi, Mice, Middle Aged, Morales-Ibanez Oriol, NEOMED College of Pharmacy, Odena Gemma, Rautou Pierre-Emmanuel, Rodrigo-Torres Daniel, Sancho-Bru Pau, Scientific reports, Seki Ekihiro, Signal Transduction, Toll-Like Receptor 4/genetics/*metabolism, Type I/genetics/*metabolism, Valla Dominique, You Min, Zou Jian
Interleukin-1beta induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes.
Tags: *Protein Biosynthesis, 2016, Ansari Mohammad Y, Cells, Chondrocytes/drug effects/metabolism/pathology, Cultured, Cyclooxygenase 2/*genetics, Department of Anatomy & Neurobiology, Dinoprostone/genetics, Fluorescence, Gene Expression Regulation, Haqqi Tariq M, Humans, Immunoprecipitation, In Situ Hybridization, Interleukin-1beta/administration & dosage/*genetics, Messenger/genetics, NEOMED College of Medicine, Nitric Oxide/metabolism, Osteoarthritis/drug therapy/*genetics/pathology, RNA, Scientific reports
Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4alpha and Protects Against Alcohol- and MCD diet-induced Liver Injury.
Tags: 2016, Alcoholic/*pathology, Alcohols/*toxicity, Animals, Carboxylic Ester Hydrolases/*metabolism, Chemical and Drug Induced Liver Injury/*pathology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Diet/*adverse effects, Fatty Liver, Gene Expression Regulation, Genetic, Hepatocyte Nuclear Factor 4/*metabolism, Hepatocytes/metabolism, Humans, Inbred C57BL, Jadhav Kavita, Knockout, Li Yuanyuan, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Promoter Regions, Protein Binding, Scientific reports, Xu Jiesi, Xu Yang, Yin Liya, You Min, Zhang Yanqiao
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.
Tags: 2016, Adapala R K, Animals, Calcium Signaling/genetics, Cappelli H C, Carcinoma, Cell Line, Cell Proliferation/drug effects, Chilian W M, Cisplatin/administration & dosage, Department of Integrative Medical Sciences, Dudley A C, Endothelium, Gene Expression Regulation, Ghosh K, Humans, Ingber D E, Keshamouni V, Klagsbrun M, Leucine/administration & dosage/analogs & derivatives, Lewis Lung/drug therapy/*genetics/pathology, Meszaros J G, Mice, NEOMED College of Medicine, Neoplastic/drug effects, Neovascularization, Oncogene, Paruchuri S, Pathologic/drug therapy/*genetics/pathology, Sulfonamides/administration & dosage, Thodeti C K, Thoppil R J, TRPV Cation Channels/agonists/biosynthesis/*genetics, Tumor, Vascular Endothelial Growth Factor A/genetics, Vascular/drug effects/*pathology
Tags: *Apoptosis, 2015, 3' Untranslated Regions, Aged, Chondrocytes/*metabolism/pathology, Department of Anatomy & Neurobiology, Down-Regulation, Experimental & molecular medicine, Female, Gene Expression Regulation, Haqqi Tariq M, Humans, Interleukin-6/*genetics, Makki Mohammad Shahidul, Male, Messenger/genetics, MicroRNAs/*genetics, Middle Aged, NEOMED College of Medicine, Osteoarthritis/*genetics/pathology, Ribonucleases/*genetics, RNA, Transcription Factors/*genetics, Up-Regulation
Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives.
Tags: 2000, Antiviral Agents/*pharmacology, Antiviral research, Callahan M, Craigo J, Cultured, DeLucia A L, Department of Integrative Medical Sciences, Female, Gene Expression Regulation, Genetic/drug effects, HIV Long Terminal Repeat/drug effects, Huang R C, Humans, Lignans/chemistry/pharmacology, Masoprocol/*analogs & derivatives/*pharmacology, NEOMED College of Medicine, Papillomaviridae/*genetics, Promoter Regions, Simian virus 40/genetics, Tumor Cells, Viral/*drug effects
Tags: *Muscle Development, 1999, Afferent Pathways/physiology, Aging/metabolism, Animals, Cell Lineage, Developmental, Fetal Proteins/metabolism, Gene Expression Regulation, Knockout, Kucera J, Mammals/anatomy & histology/*metabolism, Mice, Morphogenesis, Muscle, Muscle Contraction, Muscle Fibers, Muscle Proteins/deficiency/physiology, Muscle Spindles/physiology, Myosin Heavy Chains/*metabolism, Nerve Tissue Proteins/deficiency/physiology, Protein Isoforms/*metabolism, Rats, Skeletal/*chemistry/classification, Skeletal/chemistry/embryology/*growth & development/ultrastructure, Transgenic, Trends in neurosciences, Walro J M
Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.
Tags: *Ceruloplasmin, *Deamidation, *Heavy water metabolic labeling, *High resolution mass spectrometry, *Iron metabolism, *LC-MS/MS, *Non-enzymatic glycation, *Oxidative Stress, *Protein Processing, *Proteome dynamics, *Serotransferrin, *Type 2 diabetes mellitus, 2017, Adult, Amino Acid Sequence, Bena James, Case-Control Studies, Ceruloplasmin/genetics/*metabolism, Department of Pharmaceutical Sciences, Deuterium/metabolism, Diabetes Mellitus, Diabetic, Diet, Female, Free radical biology & medicine, Gene Expression Regulation, Glycated Hemoglobin A/genetics/metabolism, Glycosylation, Golizeh Makan, Humans, Ilchenko Serguei, Iron/*metabolism, Isotope Labeling, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Male, Middle Aged, NEOMED College of Pharmacy, Osme Abdullah, Oxidation-Reduction, Oxidative Stress, Post-Translational, Proteolysis, Sadygov Rovshan G, Transferrin/genetics/*metabolism, Type 2/diet therapy/genetics/*metabolism/pathology
Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.
Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong
Tags: *Cytochrome P-450 Enzyme System/genetics/metabolism/physiology, 2008, Animals, Biochemical pharmacology, Cytochrome P-450 CYP4A/genetics/metabolism/physiology, Department of Integrative Medical Sciences, Enzymologic, Fatty Acids/*metabolism, Gene Expression Regulation, Hardwick James P, Humans, Metabolic Diseases/enzymology/*metabolism, NEOMED College of Medicine
Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice.
Tags: 2009, Adenoviridae/genetics, Animals, Bile Acids and Salts/biosynthesis, Biochimica et biophysica acta, Cell Line, Cell Nucleus/drug effects/metabolism, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*antagonists & inhibitors/genetics/metabolism, Department of Integrative Medical Sciences, Dietary Fats/*administration & dosage/*pharmacology, Down-Regulation/drug effects, Enzymologic/drug effects, Feeding Behavior/*drug effects, Forkhead Box Protein O1, Forkhead Transcription Factors/genetics/*metabolism, Gene Expression Regulation, Gene Knockdown Techniques, Gene Transfer Techniques, Hepatocytes/drug effects/*enzymology, Humans, Inbred C57BL, Insulin Resistance, Insulin/metabolism, Lee Yoon-Kwang, Li Tiangang, Ma Huiyan, Male, Messenger/genetics/metabolism, Mice, Moore David D, NEOMED College of Medicine, Park Young Joo, RNA, RNA Interference/drug effects, Strom Stephen, Tumor
Tags: 2000, Alitretinoin, Antineoplastic Agents/*pharmacology, Biochemical and biophysical research communications, Cultured, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 4, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Gene Expression Regulation, Hardwick J P, Humans, Hydroxylation, Leukotriene B4/metabolism, Molecular Sequence Data, NEOMED College of Medicine, Tretinoin/*pharmacology, Tumor Cells, Up-Regulation, Zhang X
Binding of sequence-specific proteins to the 3'-untranslated region of vasoactive intestinal peptide mRNA.
Tags: 1995, Animals, Anterior/*metabolism, Base Sequence, Binding, Biochemical and biophysical research communications, Competitive, Cytoplasm/chemistry, Gene Expression Regulation, Genomic Library, Male, Messenger/*metabolism, Molecular Sequence Data, Pituitary Gland, Post-Transcriptional, Protein Binding, Proto-Oncogene Proteins c-fos/genetics, Rats, RNA, RNA Processing, RNA-Binding Proteins/*metabolism, RNA/metabolism, Signs S A, Sprague-Dawley, Subcellular Fractions, Tissue Distribution, Vasoactive Intestinal Peptide/*genetics, Wolford J K
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells.
Tags: 1994, Animals, Bile Acids and Salts/*pharmacology, Biochemical and biophysical research communications, Cells, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Gene Expression Regulation, Genetic, Genetic/genetics, Humans, Karam W G, Luciferases/biosynthesis/genetics, Messenger/*biosynthesis, NEOMED College of Medicine, Promoter Regions, Rats, Recombinant Fusion Proteins/biosynthesis, RNA, Steroids/*pharmacology, Thyroid Hormones/*pharmacology, Transcription, Transfection
Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases.
Tags: *Cell Movement, 2018, Arosarena Oneida A, Barr Eric W, Carcinoma, Cell Line, cell lines, Department of Anatomy & Neurobiology, Enzymologic, Extracellular Matrix, Gene Expression Regulation, Head and Neck Neoplasms/*enzymology/genetics/pathology, Human, Humans, Journal of cellular physiology, matrix metalloproteinases, Membrane Glycoproteins/genetics/*metabolism, Messenger/genetics/metabolism, NEOMED College of Medicine, neoplasm invasion, Neoplasm Invasiveness, Neoplastic, RNA, RNA Interference, Safadi Fayez F, Secreted/genetics/*metabolism, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/*enzymology/genetics/pathology, Tarr Joseph T, Thorpe Ryan, Transfection, Tumor, Yankey Hilary