Browse Items (11 total)
- Tags: Proteins
Chronic Exposure To Nicotine And Saquinavir Decreases Endothelial Notch-4 Expression And Disrupts Blood-brain Barrier Integrity
Tags: 2010, acetylcholine-receptors, Biochemistry & Molecular Biology, Choline transporter, cigarette-smoke condensate, electron-spin-resonance, endothelial cell toxicity, Geldenhuys W J, gene-expression, in-vitro, inhibitors, Journal of neurochemistry, Lockman P R, Manda V K, Mittapalli R K, Neurosciences & Neurology, Nicotine, Notch-4, osmotic pumps, parkinsons-disease, perfusion technique, protease, protease inhibitors, Proteins, ritonaivir, ROS, saquinqavir, tight junction
Peptide-based Antibodies against Glutathione-binding Domains Suppress Superoxide Production Mediated by Mitochondrial Complex I
Tags: 2010, Biochemistry & Molecular Biology, bovine heart-mitochondria, Chen C A, Chen C L, Chen J F, Chen Y R, generation, Journal Article or Conference Abstract Publication, Journal of Biological Chemistry, Kaumaya P T P, nadh-ubiquinone oxidoreductase, nitric-oxide, Oxidative Stress, postischemic heart, Proteins, radical formation, Rawale S, s-nitrosylation, site, Zweier J L
Metabolism of phenytoin by the gingiva of normal humans: The possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia
Tags: 1996, Clinical Pharmacology & Therapeutics, clinical report, cyclosporine-a, cytochrome P450, enlargement, Hardwick J P, hepatotoxicity, Holtzman J L, Journal Article, Microsomes, monoclonal-antibodies, overgrowth, Park S S, Pharmacology & Pharmacy, Pihlstrom B, Proteins, severity, Wrighton S A, Zhou L X
Identification of Multiple Metabolic Enzymes from Mice Cochleae Tissue Using a Novel Functional Proteomics Technology
Tags: 2015, Animal tissues, Bao J X, Beef, Biology, Cancer, cancer metabolism, cell metabolism, Cochlea, draft, Drug Therapy, E coli, Electrophoresis, Elution, Enzymatic activity, Enzyme assays, Enzyme metabolism, Enzymes, Feasibility Studies, Functional analysis, Gel electrophoresis, Genes, Genomics, Hearing impairment, Journal Article, Kinases, Li H, Liang R Q, Mass spectrometry, Mass spectroscopy, Medicine, messenger-rna, Metabolism, Mice, NAD(P)H oxidase, NADH, Neurobiology, Neurosciences, nicotinamide adenine dinucleotide, Noise, otolaryngology, Oxidation-reduction reactions, Phosphatase, PloS one, PROTEIN expression, Proteins, Proteomes, proteomics, Science & Technology - Other Topics, Sciences: Comprehensive Works, Scientific imaging, Studies, Substance abuse treatment, Technology, United States--US, Wang D L
alpha(2)-Macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14
Tags: 2000, alpha-2-macroglobulin, alpha-macroglobulin, Binding, Biochemical Journal, Biochemistry & Molecular Biology, factor-beta, Glycodelin, Human, immunosuppressive, inhibition, Journal Article, Koo P H, nerve growth-factor, Phosphorylation, phytohemagglutinin, pregnancy proteins, Proteins, Rachmilewitz J, Receptor, Riely G J, serum carrier, serum transport, signal-transduction, Tykocinski M L
Tags: 2019, Achondroplasia, Apoptosis, Arthritis, biomechanics, Bone (axial), Bone dysplasia, Bones, Cartilage, Cartilage (articular), Cartilage oligomeric matrix protein, Chondrocytes, Chromosome 19, Chromosomes, Dwarfism, Dysplasia, Elbow, Elbow (anatomy), Epiphysis, Evanston, Extremities, Feet, Gait, Guirguis James, Hand (anatomy), Hip, Intelligence, Joint diseases, Knee (anatomy), Kyphosis, Medical Sciences--Pediatrics, Mutation, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, October 2019 Update, Orthopedics, Pediatrics, Plates (structural members), Proteins, Radiographs, Radiography, Skeleton, Thorax, Vertebra, Vertebrae, Weiner Dennis S
Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction.
Tags: 2012, Agarwal U, Animal Studies, Apoptosis – Physiology, Cardiovascular System Physiology, Cell Movement – Physiology, Cell Physiology, Cell Surface, Cell Surface – Metabolism, Cells, Circulation, Coronary Circulation – Physiology, Cytokines – Metabolism, Department of Integrative Medical Sciences, Dong F, Finan A, Gene Expression – Physiology, Harvey J, Mice, myocardial infarction, Myocardial Infarction – Pathology, Myocardial Infarction – Therapy, Myocardium, NEOMED College of Medicine, Penn M S, Proteins, Receptors, Stem Cells – Metabolism, Stem Cells – Transplantation, Weber K
Apolipoprotein A1 regulates coenzyme Q10 absorption, mitochondrial function, and infarct size in a mouse model of myocardial infarction.
Tags: *Disease Models, 2014, Animal, Animal Studies, Animals, Antioxidants – Administration and Dosage, Antioxidants – Metabolism, Antioxidants – Pharmacokinetics, Antioxidants – Therapeutic Use, Antioxidants/administration & dosage/*metabolism/pharmacokinetics/therapeutic use, Apolipoprotein A-I/blood/genetics/*metabolism, Apolipoproteins, Apolipoproteins – Blood, Apolipoproteins – Metabolism, Biological, Cardiotonic Agents – Administration and Dosage, Cardiotonic Agents – Metabolism, Cardiotonic Agents – Pharmacokinetics, Cardiotonic Agents – Therapeutic Use, Cardiotonic Agents/administration & dosage/metabolism/pharmacokinetics/therapeutic use, Coenzyme Q, Coenzyme Q – Administration and Dosage, Coenzyme Q – Metabolism, Coenzyme Q – Pharmacokinetics, Coenzyme Q – Therapeutic Use, Dadabayev Alisher R, Dietary Supplements, Electron Transport – Drug Effects, Electron Transport Complex II/chemistry/metabolism, Electron Transport Complex III/chemistry/metabolism, Electron Transport/drug effects, Heart – Drug Effects, Heart/drug effects, Heart/drug effects/enzymology/*metabolism, Hypoalphalipoproteinemias/physiopathology, Inborn Errors – Physiopathology, Injections, Intestinal Absorption, Intraperitoneal, Knockout, Latchoumycandane Calivarathan, Lesnefsky Edward J, Lipid Metabolism, Male, McIntyre Thomas M, Mice, Mitochondria, Mitochondria – Drug Effects, Mitochondria – Metabolism, Models, Myocardial Infarction – Etiology, Myocardial Infarction – Metabolism, Myocardial Infarction – Pathology, Myocardial Infarction – Therapy, Myocardial Infarction/etiology/metabolism/pathology/*therapy, Myocardial Reperfusion Injury – Blood, Myocardial Reperfusion Injury – Metabolism, Myocardial Reperfusion Injury – Pathology, Myocardial Reperfusion Injury – Prevention and Control, Myocardial Reperfusion Injury/blood/metabolism/pathology/prevention & control, Myocardium, Myocardium – Metabolism, Myocardium – Pathology, Myocardium/enzymology/*metabolism/pathology, Penn Marc S, Proteins, Proteins – Metabolism, The Journal of nutrition, Tissue Distribution, Ubiquinone/administration & dosage/*analogs & derivatives/metabolism/pharmacokinetics/therapeutic use, Yin Guotian
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Tags: 2018, AMP-activated protein kinase, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cells – Drug Effects, Cells – Pathology, Department of Pharmaceutical Sciences, Diet, Disease Models, Eye Proteins/genetics, Female, G-Protein-Coupled – Metabolism, G-Protein-Coupled/*metabolism, Glaucoma, Glaucoma – Complications, Glaucoma – Pathology, Glaucoma/*complications/pathology, Harun-Or-Rashid Mohammad, Impact of Events Scale, Inbred DBA, Inflammation – Etiology, Inflammation – Prevention and Control, Inflammation hydroxycarboxylic acid receptor, Inflammation/*etiology/*prevention & control, Inman Denise M, Journal of neuroinflammation, Ketogenic diet, Ketogenic/methods, Male, Membrane Glycoproteins, Membrane Glycoproteins/genetics, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia/drug effects/pathology, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Neuroprotection/drug effects/*physiology, NLR Family, Optic Nerve – Pathology, Optic Nerve/pathology, Phosphotransferases – Metabolism, Proteins, Pyrin Domain-Containing 3 Protein/genetics/metabolism, Receptors, Retina – Drug Effects, Retina – Pathology, Retinal Ganglion Cells/drug effects/*pathology, Transgenic
On the path to untreatable infections: colistin use in agriculture and the end of 'last resort' antibiotics.
Tags: *Agriculture, *Antibiotic resistance, *Colistin, *Drug Resistance, 2016, Agriculture, Animal Husbandry, Anti-Bacterial Agents/*therapeutic use, Antibiotics – Therapeutic Use, Bacterial, Bonomo Robert A, Colistin – Analogs and Derivatives, Colistin – Therapeutic Use, Colistin/analogs & derivatives/*therapeutic use, Comparative Studies, Department of Internal Medicine, Drug Resistance, Escherichia coli, Escherichia Coli – Physiology, Escherichia coli Proteins/genetics, Escherichia coli/genetics/*physiology, European Union, Evaluation Research, Expert review of anti-infective therapy, Human, Humans, Microbial, Multicenter Studies, Multiple, NEOMED College of Medicine, Proteins, Smith Tara C, Validation Studies, Watkins Richard R
Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.
Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong