Browse Items (37 total)
- Tags: Molecular
230. Molecular Typing of Streptococcus pyogenes Isolates Collected at Mongolian Hospital (Ulaanbaatar, Mongolia).
Tags: 2019, antibiotic resistance, antimicrobial susceptibility, Bacterial, CENTERS for Disease Control & Prevention (U.S.), China, clone cells, Communicable Diseases, Davaadash Bulgan, Disclosure, Disease Outbreaks, DRUG resistance in bacteria, Epidemiology, Genes, ichthyosis, Infection, Journal Article, Kadariya Jhalka, low income, LOW-income countries, Mackey Samantha, Medical, Molecular, MOLECULAR epidemiology, Mongolia, Morbidity, Mortality, multi-antibiotic resistance, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Open forum infectious diseases, Polymerase Chain Reaction, sequence tagged sites, Smith Tara, sodium thiosulfate, Streptococcus pyogenes, surveillance, Thapaliya Dipendra, TOXIC shock syndrome, ULAANBAATAR (Mongolia), vaccine development, x-linked
The Clinical Relevance Of Penicillin-resistant Streptococcus Pneumoniae: A New Perspective
Tags: 2006, antibiotic-resistance, bacteremia, Boex J R, Clinical Infectious Diseases, Community-acquired pneumonia, Department of Family & Community Medicine, Epidemiology, File T M, Immunology, Infectious Diseases, metaanalysis, Microbiology, Molecular, Mortality, NEOMED College of Medicine, outcomes, pneumococcal pneumonia, susceptibility, Tan J S, united-states
Gene Expression in Slipped Capital Femoral Epiphysis
Tags: 2009, analysis, Cancer, chondrocyte apoptosis, Fixation, growth-plate, Jacquet R, Journal Article, Journal of Bone and Joint Surgery-American Volume, Landis W J, laser-capture microdissection, Lowder E, microarrays, Molecular, Orthopedics, PCR, Scharschmidt T, Schrickel T, shear, Surgery, tissues, Weiner D
Emergence of methicillin-resistant Staphylococcus aureus USA300 genotype as a major cause of late-onset nosocomial pneumonia in intensive care patients in the USA
Tags: 2013, blood-stream infections, CA-MRSA, Community-acquired pneumonia, Community-associated methicillin-resistant Staphylococcus aureus, Community-associated MRSA, Disease, Epidemiology, File T M, Ford K D, Grp Impact-Hap Study, Haque N Z, Infectious Diseases, intensive care, International Journal of Infectious Diseases, Jabrocki B, Journal Article, Molecular, Mortality, MRSA, mrsa strains, Nosocomial pneumonia, outcomes, panton-valentine leukocidin, Pasquale T R, Peyrani P, Ramirez J A, risk-factors, Salstrom S J, Scerpella E G, ventilator-associated pneumonia, Wiemken T L, Zervos M J
The complete nucleotide sequence of human liver cytochrome b5 mRNA.
The characterization of three types of partially processed mRNA and two pseudogenes for human liver cytochrome b5.
Tags: 1989, Amino Acid Sequence, Base Sequence, Biochemical and biophysical research communications, Cloning, Cytochrome b Group/*genetics, Cytochromes b5, DNA/genetics, Humans, Liver/*physiology, Molecular, Molecular Sequence Data, Post-Transcriptional, Pseudogenes, RNA Processing, Steggles A W, Yoo M
Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1.
Tags: 1999, Animals, Base Sequence, Blotting, Cell Line, Chiang J Y, Chromosome Mapping, Cloning, Codon, Complementary/biosynthesis/*isolation & purification, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 7, Department of Integrative Medical Sciences, DNA, Genetic, Genetic/genetics, Humans, Hydroxycholesterols/metabolism, Initiator, Javitt N B, Journal of lipid research, Luciferases/genetics, Martin K O, Mice, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Northern, Nucleic Acid, Promoter Regions, Regulatory Sequences, Steroid Hydroxylases/*genetics/metabolism, Transcription, Transfection, Wu Z
Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7alpha-hydroxylase gene (CYP7A).
Tags: *Gene Expression Regulation, *Receptors, 1997, Animals, Chiang J Y, Chickens, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Circadian Rhythm, COUP Transcription Factor I, COUP Transcription Factor II, COUP Transcription Factors, Crestani M, Department of Integrative Medical Sciences, DNA-Binding Proteins/*metabolism, Electrophoresis, Enzymologic, Genetic, Glucocorticoid/*genetics, Models, Molecular, NEOMED College of Medicine, Nuclear Proteins/*metabolism, Polyacrylamide Gel, Promoter Regions, Rats, Receptors, Recombinant Proteins/genetics/metabolism, Retinoic Acid/*metabolism, Retinoid X Receptors, Steroid, Stroup D, The Journal of biological chemistry, Transcription Factors/*metabolism
Cloning and characterization of two major 3-methylcholanthrene inducible hamster liver cytochrome P450s.
Tags: 1990, Amino Acid Sequence, Animals, Archives of biochemistry and biophysics, Base Sequence, Chiang J Y, Cloning, Cricetinae, Cytochrome P-450 Enzyme System/biosynthesis/*genetics, Department of Integrative Medical Sciences, Enzyme Induction, Female, Humans, Immunoblotting, Inbred Strains, Lai T S, Liver/drug effects/*enzymology, Liver/enzymology, Male, Mesocricetus, Methylcholanthrene/*pharmacology, Microsomes, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Nucleic Acid, Nucleic Acid Hybridization, Phenobarbital/pharmacology, Rats, Reference Values, Restriction Mapping, Sequence Homology
Polymorphisms of human cholesterol 7 alpha-hydroxylase.
Tags: 1992, Amino Acid Sequence, Base Sequence, Biochemical and biophysical research communications, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Department of Integrative Medical Sciences, DNA/genetics, Genetic, Humans, Karam W G, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Oligodeoxyribonucleotides/chemistry, Polymerase Chain Reaction, Polymorphism, Restriction Mapping
The nucleotide sequence of rabbit liver cytochrome b5 mRNA.
Tags: 1988, Amino Acid Sequence, Animals, Base Sequence, Chromosome Deletion, Cloning, Cytochrome b Group/*genetics, Cytochromes b5, Dariush N, Fisher C W, Genes, Liver/*metabolism, Messenger/*genetics, Molecular, Molecular Sequence Data, Protein sequences & data analysis, Rabbits, RNA, Steggles A W
Isolation and characterization of cDNA clones for human, bovine and rabbit liver cytochrome b5 mRNA's.
Tags: 1989, Amino Acid Sequence, Animals, Base Sequence, Cattle, Chickens, Cloning, Cristiano R J, Cytochromes b5/blood/*genetics, Dariush N, DNA/*isolation & purification, Erythrocytes/enzymology, Humans, Liver/*enzymology, Messenger/*genetics, Molecular, Molecular Sequence Data, Nucleic Acid, Progress in clinical and biological research, Rabbits, RNA, Sequence Homology, Steggles A W, Yoo M
Hormonal regulation of the cholesterol 7 alpha-hydroxylase gene (CYP7).
Tags: *Promoter Regions, *Transcription, 1995, Animals, Base Sequence, Cell Count, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Crestani M, Cultured, Cyclic AMP/pharmacology, Department of Integrative Medical Sciences, Enzymologic/*physiology, Gene Expression Regulation, Genetic, Hormones/*pharmacology, Journal of lipid research, Luciferases/genetics, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Phorbol Esters/pharmacology, Rats, Second Messenger Systems/physiology, Stroup D, Transfection, Tumor Cells
Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter.
Tags: *Promoter Regions, 1994, Animals, Antigens, Base Sequence, Bile Acids and Salts/*metabolism, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Cloning, Deoxyribonuclease I, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Enzymologic, Gene Expression Regulation, Genetic, Humans, Luciferases/genetics, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Nuclear Proteins/metabolism, Oligodeoxyribonucleotides, Polyomavirus Transforming/genetics, Rats, Recombinant Fusion Proteins/genetics/metabolism, Sprague-Dawley, Stroup D, The Journal of biological chemistry, Thyroid Hormones/genetics
Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene.
Tags: *Promoter Regions, 1992, Amino Acid Sequence, Animals, Base Sequence, Biochimica et biophysica acta, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Department of Integrative Medical Sciences, DNA, Genetic, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Rats, Restriction Mapping, Wang D P, Yang T P
Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).
Tags: *DNA-Binding Proteins, 2003, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Bile Acids and Salts/*pharmacology, Binding Sites/genetics, Cell Line, Chen Wenling, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholestanetriol 26-Monooxygenase, Cloning, Cultured, Cytoplasmic and Nuclear/genetics/metabolism, Department of Integrative Medical Sciences, DNA, DNA/chemistry/genetics, Dose-Response Relationship, Drug, gene, Gene Expression Regulation/drug effects, Genetic/*genetics, Hepatocyte Nuclear Factor 4, Humans, Luciferases/genetics/metabolism, Molecular, Molecular Sequence Data, Mutagenesis, Mutation, NEOMED College of Medicine, Phosphoproteins/genetics/*metabolism, Promoter Regions, Receptors, Recombinant Fusion Proteins/genetics/metabolism, Response Elements/genetics, Sequence Analysis, Site-Directed, Steroid Hydroxylases/*genetics, Transcription Factors/genetics/*metabolism, Transfection, Tumor Cells
Exploring Adenosine Receptor Ligands: Potential Role in the Treatment of Cardiovascular Diseases.
Tags: *drug discovery, *Ligands, 2017, Adenosine/metabolism, Animals, Atherosclerosis, Cardiac death, Cardiovascular Diseases/drug therapy/metabolism, Cardiovascular System/metabolism, Department of Integrative Medical Sciences, Geldenhuys Werner J, Hanif Ahmad, Humans, Hydrogen Bonding, Models, Molecular, Molecular Structure, Molecules (Basel, Switzerland), myocardial infarction, Nayeem Mohammed A, NEOMED College of Medicine, Protein Binding, Purinergic P1/*chemistry/*metabolism, Receptors, Signal Transduction, Structure-Activity Relationship, Vascular tone, Yun June
Genetics of Skeletal Evolution in Unusually Large Mice from Gough Island.
Tags: *body size, *complex trait, *Evolution, *island syndrome, *phenotypic extreme, *pleiotropy, *Quantitative Trait Loci, *skeletal evolution, 2016, Animals, Body Size/*genetics, Bone and Bones/*anatomy & histology, Broman Karl W, Female, Ford Irene N, Genetic Pleiotropy, Genetics, Gray Melissa M, Hogan Caley A, Islands, Male, Mice/*genetics, Molecular, Parmenter Michelle D, Payseur Bret A, Vinyard Christopher J
Human quadrupeds, primate quadrupedalism, and Uner Tan Syndrome.
Tags: *Primates, 2014, Adolph Karen E, Adult, Animals, Child, Cole Whitney G, Department of Anatomy & Neurobiology, Evolution, Female, Gait/*physiology, Humans, Infant, Male, Molecular, NEOMED College of Medicine, PloS one, Posture/physiology, Raichlen David A, Robinson Scott R, Shapiro Liza J, Syndrome, Walking/*physiology, Young Jesse W
Something completely different?
Tags: 1996, Animals, Blotting, Brain/*enzymology, Chen L, Cloning, Complementary, Cytochrome P-450 Enzyme System/*genetics/isolation & purification, Department of Integrative Medical Sciences, DNA, Hardwick J P, Human & experimental toxicology, Kidney/enzymology, Liver/enzymology, Molecular, NEOMED College of Medicine, Northern, Rats
Mineral deposition in the extracellular matrices of vertebrate tissues: identification of possible apatite nucleation sites on type I collagen.
Tags: *Calcification, 2009, Animals, Apatites/*metabolism, Calcium/metabolism, Cells, tissues, organs, Collagen Type I/chemistry/*metabolism, Extracellular Matrix/*metabolism, Humans, Landis William J, Microfibrils/chemistry, Models, Molecular, Phosphates/metabolism, Physiologic, Silver Frederick H, Vertebrates/*metabolism
Virtual screening to identify novel antagonists for the G protein-coupled NK3 receptor.
Tags: *Models, *Narcotic Antagonists, *Quantitative Structure-Activity Relationship, 2010, Animals, Binding, Calcium Signaling/drug effects, CHO Cells, Competitive, Cricetinae, Cricetulus, Databases, Factual, Geldenhuys Werner J, Humans, Journal of medicinal chemistry, Kuzenko Stephanie R, Ligands, Molecular, Neurokinin-3/*antagonists & inhibitors/chemistry, Opioid/chemistry, Quinolines/*chemistry/pharmacology, Radioligand Assay, Receptors, Simmons Mark A
Protein thiyl radical mediates S-glutathionylation of complex I.
Tags: *Oxidative Stress, 2012, Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Cattle, Cell Line, Chen Chwen-Lih, Chen Jingfeng, Chen Yeong-Renn, Cyclic N-Oxides/chemistry/pharmacology, Cysteine/chemistry/*metabolism, Department of Integrative Medical Sciences, Electron Transport Complex I/chemistry/*metabolism, Free radical biology & medicine, Free Radical Scavengers/chemistry/pharmacology, Free Radicals/chemistry/*metabolism, Glutathione/chemistry/*metabolism, Green Kari B, Heart/enzymology/metabolism, Kang Patrick T, Mice, Mitochondria, Models, Molecular, Molecular Sequence Data, Muscle Cells/drug effects/metabolism, NEOMED College of Medicine, Onium Compounds/pharmacology, Peptide Fragments/chemistry, Peptide Mapping, Protein, Rats, Rotenone/pharmacology, Structural Homology, Superoxides/metabolism, Zhang Liwen
The role of the N-terminal and mid-region residues of substance P in regulating functional selectivity at the tachykinin NK1 receptor.
Tags: 2008, Amino Acid Sequence, Animals, Beard Debbie J, Binding, Calcium Signaling/physiology, CHO Cells, Competitive/drug effects, Cricetinae, Cricetulus, Dose-Response Relationship, Drug, European journal of pharmacology, Iodine Radioisotopes, Ligands, Models, Molecular, Molecular Sequence Data, Neurokinin-1/chemistry/drug effects/*metabolism, Perrine Shane A, Rats, Receptors, Simmons Mark A, Substance P/chemistry/drug effects/*physiology, Young John K
A scaffold hopping approach to identify novel monoamine oxidase B inhibitors.
Tags: *Monoamine Oxidase/chemistry/metabolism, 2012, Benzofurans/chemistry/pharmacology, Bioorganic & medicinal chemistry letters, Carroll Richard T, Enzyme Activation/drug effects, Flavonoids/chemistry/pharmacology, Funk Max O, Geldenhuys Werner J, Humans, Inhibitory Concentration 50, Models, Molecular, Molecular Structure, Monoamine Oxidase Inhibitors/*chemistry/*pharmacology, Protein Binding/drug effects, Small Molecule Libraries, Structure-Activity Relationship, Van der Schyf Cornelis J
3D-Quantitative structure-activity relationship and docking studies of the tachykinin NK3 receptor.
Tags: *Quantitative Structure-Activity Relationship, 2011, Binding Sites, Bioorganic & medicinal chemistry letters, Computer Simulation, Drug Design, Geldenhuys Werner J, Humans, Ligands, Models, Molecular, Neurokinin-3/*chemistry/metabolism, Protein Structure, Quinolines/chemistry, Receptors, Simmons Mark A, Tertiary
Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B.
Tags: 2011, Animals, Awale Prabha S, Bioorganic & medicinal chemistry letters, Carroll Richard T, Dluzen Dean E, Funk Max O, Geldenhuys Werner J, Humans, Inbred C57BL, Male, Mice, Models, Molecular, Molecular Structure, Monoamine Oxidase Inhibitors/chemical synthesis/chemistry/*pharmacology, Monoamine Oxidase/*metabolism, Stereoisomerism, Stinnett Hilary, Structure-Activity Relationship, Thiazolidinediones/chemical synthesis/chemistry/*pharmacology
Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.
Tags: 2010, Bioorganic & medicinal chemistry letters, Carroll Richard T, Darvesh Altaf S, Department of Pharmaceutical Sciences, Funk Max O, Geldenhuys Werner J, Models, Molecular, Monoamine Oxidase Inhibitors/chemistry/*pharmacology, Monoamine Oxidase/*drug effects, NEOMED College of Pharmacy, Structure-Activity Relationship, Van der Schyf Cornelis J
3-D-QSAR and docking studies on the neuronal choline transporter.
Tags: 2010, Allen David D, Binding Sites, Bioorganic & medicinal chemistry letters, Blood-Brain Barrier/metabolism, Computer Simulation, Geldenhuys Werner J, Lockman Paul R, Membrane Transport Proteins/*chemistry/metabolism, Models, Molecular, Neurons/*metabolism, Quantitative Structure-Activity Relationship, Quaternary Ammonium Compounds/chemistry
3D-QSAR and docking studies on transforming growth factor (TGF)-beta receptor 1 antagonists.
Structure-activity relationships of pentacycloundecylamines at the
Tags: 2007, Amines/chemical synthesis/chemistry/*pharmacology, Animals, Bioorganic & medicinal chemistry, Bloomquist Jeffrey R, Brain/drug effects, Dizocilpine Maleate/pharmacology, Excitatory Amino Acid Antagonists/*pharmacology, Geldenhuys Werner J, Inbred ICR, Ion Channels, Malan Sarel F, Male, Mice, Models, Molecular, N-Methyl-D-Aspartate/*antagonists & inhibitors, Phencyclidine/analogs & derivatives, Piperidines/pharmacology, Radioligand Assay, Receptors, Structure-Activity Relationship, Synaptosomes/*drug effects, Thiophenes/pharmacology, Van der Schyf Cornelis J
The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.
Tags: 2019, Acid Anhydride Hydrolases/*metabolism, Animals, Ansari Mohammad Yunus, Baculoviridae/genetics, Bellur Asutosh, Cercopithecus aethiops, Cloning, Conventional mRNA capping, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression, Genetic Vectors/genetics, Messenger/*genetics/*metabolism, Molecular, Morbillivirus, mRNA capping, NEOMED College of Medicine, Peste-des-petits-ruminants virus L protein, Peste-des-petits-ruminants virus/*physiology, Peste-des-Petits-Ruminants/*virology, PPRV, Rajagopalan Deepa, RNA, RNA Caps/*metabolism, RNA triphosphatase, Shaila Melkote Subbarao, Shanmugam Purnima, Singh Piyush Kumar, Vero Cells, Viral Proteins/*metabolism, Virus Genes
HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing.
Tags: *Protein Processing, 2009, Animals, Archives of virology, Bower John R, Cercopithecus aethiops, Chatterjee Somik, Cismowski Mary J, Cloning, Gene Expression, Herpesvirus 1, Herpesvirus 2, Human/*genetics, Molecular, Post-Translational, Rosenthal Kenneth Steven, Vero Cells, Viral Envelope Proteins/*metabolism, Viral Proteins/genetics/*metabolism, Wang Jason W
Aspects of mineral structure in normally calcifying avian tendon.
The isolation and characterization of the human cytochrome b5 gene.
Tags: 1995, Animals, Base Sequence, Biochemical and biophysical research communications, Cattle, Cell Line, Cloning, Cosmids, Cultured, Cytochromes b5/biosynthesis/*genetics, DNA Primers, DNA/genetics/isolation & purification, Gene Library, Genetic, Giordano S J, Hominidae/*genetics, Humans, Introns, Li X R, Luciferases/biosynthesis, Messenger/analysis/biosynthesis, Molecular, Molecular Sequence Data, Polymerase Chain Reaction, Promoter Regions, Rabbits, RNA, Steggles A W, Transfection, Tumor Cells, Yoo M
Promoter activity and regulation of the CYP4F2 leukotriene B(4) omega-hydroxylase gene by peroxisomal proliferators and retinoic acid in HepG2 cells.
Tags: *Gene Expression Regulation, *Promoter Regions, 2000, Amino Acid Sequence, Archives of biochemistry and biophysics, Base Sequence, Cell Line, Chen L, Cloning, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 4, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, DNA, DNA Footprinting, Enzymologic, Exons, Genes, Genetic, Genetic/drug effects, Hardwick J P, Humans, Introns, Leukotriene B4/metabolism, Mixed Function Oxygenases/metabolism, Models, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Peroxisome Proliferators/*metabolism, Receptors, Reporter, Retinoic Acid Receptor alpha, Retinoic Acid/metabolism, Sequence Analysis, Transcription, Transcription Factors/metabolism, Transfection, Tretinoin/*metabolism, Zhang X
Genomic cloning, sequencing, and analysis of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7).
Tags: 1993, Amino Acid, Amino Acid Sequence, Animals, Archives of biochemistry and biophysics, Base Sequence, Blotting, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Cloning, Crestani M, Cricetinae, Department of Integrative Medical Sciences, DNA/genetics/isolation & purification, Galli G, Genomic Library, Humans, Liver/enzymology, Mesocricetus/*genetics, Messenger/biosynthesis/metabolism, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Northern, Poly A/biosynthesis/metabolism, Rats, Restriction Mapping, RNA, Sequence Homology, Southern