Browse Items (6 total)
- Tags: Tertiary
A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.
Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques
Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia.
Tags: *Acute lymphoblastic leukemia, *Cancer, *Co-culture model, *Lipids, *Lipoprotein lipase, *Metabolism, 2018, Amides/chemistry/metabolism/pharmacology, Antineoplastic Agents/*chemistry/metabolism/pharmacology, Binding Sites, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Coculture Techniques, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dyslipidemias/complications/metabolism/pathology, Geldenhuys Werner J, Gibson Laura F, Humans, Lipoprotein Lipase/antagonists & inhibitors/*metabolism, Mesenchymal Stem Cells/cytology/metabolism, Molecular Docking Simulation, Nair Rajesh R, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Piktel Debbie, Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications/metabolism/pathology, Protein Binding, Protein Structure, Sadana Prabodh, Serum Albumin/chemistry/metabolism, Tertiary, Tumor
Tags: *Quantitative Structure-Activity Relationship, 2013, Amines/*chemistry/metabolism, Aza Compounds/chemistry, Binding Sites, Bioorganic & medicinal chemistry letters, Geldenhuys Werner J, Kinetics, Malan Sarel F, Molecular Docking Simulation, Novotny Nicholas, Protein Binding, Protein Structure, Receptors, sigma/*chemistry/metabolism, Tertiary, Van der Schyf Cornelis J
Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.
Tags: 2012, Al-Baghdadi Osamah B, Alkaloids/*chemistry/isolation & purification/pharmacology, Animals, Benzodioxoles/*chemistry/isolation & purification/pharmacology, Binding Sites, Bioorganic & medicinal chemistry letters, Blood-Brain Barrier/drug effects, Bovine/metabolism, Cattle, Geldenhuys Werner J, Humans, Hydrogen Bonding, Molecular Docking Simulation, Monoamine Oxidase Inhibitors/*chemistry/isolation & purification/pharmacology, Monoamine Oxidase/*chemistry/metabolism, Parkinson Disease/metabolism/pathology, Piper nigrum/*chemistry, Piperidines/*chemistry/isolation & purification/pharmacology, Polyunsaturated Alkamides/*chemistry/isolation & purification/pharmacology, Prater Natalie I, Protein Binding, Protein Structure, Serum Albumin, Tertiary, Van der Schyf Cornelis J
Tags: *Quantitative Structure-Activity Relationship, 2011, Binding Sites, Bioorganic & medicinal chemistry letters, Computer Simulation, Drug Design, Geldenhuys Werner J, Humans, Ligands, Models, Molecular, Neurokinin-3/*chemistry/metabolism, Protein Structure, Quinolines/chemistry, Receptors, Simmons Mark A, Tertiary
Design and use of peptide-based antibodies decreasing superoxide production by mitochondrial complex I and complex II.
Tags: *Electron Transport Complex I/antagonists & inhibitors/chemistry/immunology/metabolism, *Electron Transport Complex II/antagonists & inhibitors/chemistry/immunology/metabolism, *Mitochondria, *Mitochondrial Proteins/antagonists & inhibitors/chemistry/immunology/metabolism, *Peptides/chemistry/immunology/metabolism, 2011, Amino Acid Motifs, Animals, Biopolymers, Cattle, Chen Yeong-Renn, Department of Integrative Medical Sciences, Female, Heart/chemistry/immunology/metabolism, Kang Patrick T, Kaumaya Pravin P T, NEOMED College of Medicine, Protein Structure, Rabbits, Tertiary, Yun June